Pyrethrum allergic contact dermatitis in humans - Real?, common?, or not documented? An evidence-based approach

Cutaneous and Ocular Toxicology

Volumn 25, Issue 4, 2006, Pages 287-308

  Osimitz, Thomas G ^a   Franzosa, Jill A ^a   Maciver, Donald R ^b   Maibach, Howard I ^c  

^a Science Strategies LLC   (United States)

^b University of California San Francisco ^*

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Allergic contact dermatitis; Compositae; Cross sensitivity; Insecticide; Pesticide; Pyrethrin; Pyrethrosin; Pyrethrum; Sesquiterpene lactones; Type IV hypersensitivity

Indexed keywords

2 PROPANOL; ACYLGLYCEROL; BETA AMYRIN; BUTYLCRESOL; CAROTENOID; CINERIN; FATTY ACID DERIVATIVE; FRAGRANCE; INSECTICIDE; JASMOLIN; KEROSENE; PHTHALIC ACID DIETHYL ESTER; PROPYLENE GLYCOL; PYRETHROID; PYRETHROSIN; SALICYLIC ACID METHYL ESTER; SESQUITERPENE LACTONE DERIVATIVE; STEROL DERIVATIVE; TARAXASTEROL; TERPENOID; TERPINEOL; TRITON X 100; WAX;

CHEMICAL COMPOSITION; CLINICAL FEATURE; CROSS ALLERGY; CROSS REACTION; ECZEMA; ERYTHEMA; ERYTHEMA MULTIFORME; EVIDENCE BASED MEDICINE; EXPOSURE; FACE ERYTHEMA; FLOWER; HUMAN; MACULOPAPULAR RASH; NONHUMAN; PATCH TEST; PYRETHRUM; RAGWEED; RASH; REVIEW; SENSITIZATION; SKIN ALLERGY; SYMPTOMATOLOGY;

ALLERGENS; CHRYSANTHEMUM CINERARIIFOLIUM; DERMATITIS, ALLERGIC CONTACT; EVIDENCE-BASED MEDICINE; FEMALE; HUMANS; MALE; PATCH TESTS; PESTICIDES; PYRETHRINS;

AMBROSIA; ASTERACEAE;

EID: 33845696844     PISSN: 15569527     EISSN: 15569535     Source Type: Journal    
DOI: 10.1080/15569520601013392     Document Type: Review

References (61)

1. Fisher A. Contact Dermatitis, 3rd ed. Philadelphia: Lea & Febiger, 1986.
2. Bhat BK. Breeding methodologies applicable to pyrethrum. In: Casida J, Quistad G, eds. Pyrethrum Flowers. New York: Oxford University Press; 1995:67-94.
3. Wainaina JMG. Pyrethrum flowers - production in Africa. In: Casida J, Quistad G, eds. Pyrethrum Flowers. New York: Oxford University Press; 1995:49-54.
4. Gnadinger CB. Pyrethrum Flowers, 2nd ed. Minneapolis: McLaughlin Gormley King Co., 1936.
5. Maciver DR. Constituents of pyrethrum extract. In: Casida J, Quistad G, eds. Pyrethrum Flowers. New York: Oxford University Press; 1995:108-122.
6. White IR, Lovell CR, Cronin E. Antioxidants in cosmetics. Contact Dermatitis 1984; 11:265-267.
7. Le Coz CJ, Schbeider GA. Coatact dermatitis form tertiary- butylhydroquinone in hair dye, with cross sensitivity to BHA and BHT. Contact Dermatitis 1998; 39:39.
8. Paulsen E. Compositae dermatitis: A survey. Contact Dermatitis 1992; 26:76-86.
9. Rose WG, Haller HL. Constituents of pyrethrum flowers XI. J Org Chem 1937; 2:484-488.
10. Barton DHR, Bockman OC, de Mayo P. Sesquiterpenoids, part XII. Further investigations of the chemistry of pyrethrosin. J Chem Soc 1960; 2263-2271.
11. Mitchell JC, Dupuis G. Allergic contact dermatitis from sesquiterpenoids of the Compositae family of plants. Br J Dermatol 1971; 84:139-150.
12. Hausen BM, Schultz KH. Chrysanthemum allergy III. Identification of the allergens. Arch Dermatol Res 1976; 255:111-121.
13. Bleumink E, Mitchell JC, Geismann TA, Towers GH. Contact hypersensitivity to sesquiterpene lactones in Chyrsanthemum dermatitis. Contact Dermatitis 1976; 2:81-88.
14. Hausen BM. The sensitizing capacity of Compositae plants. III. Test results and crossreactions in Compositae-sensitive patients. Dermatologica 1979; 159:1-11.
15. Mitchell JC. Compositae and Frullania phytodermatitis. Acta Derm Venerol Suppl 1987; 134:69-76.
16. Guin JD. Sesquiterpene-lactone dermatitis. Immun Allergy Clin North Am 1989; 9:447-461.
17. Mitchell JC, Fritig B, Singh B, Towers GH. Allergic contact dermatitis from Frullania and Compositae. The role of sesquiterpene lactones. J Invest Dermatol 1970; 54:233-239.
18. Baer RL. Cross sensitisation phenomena. In: MacKenna R, ed. Modern Trends in Dermatology. London: Butterworth; 1954.
19. Fisher A. Some immunologic phenomena in treatment of and patch testing for ragweed oil dermatitis. J Invest Dermatol 1952; 19:271-279.
20. Crounse RG. Plant dermatitis due to the Compositae (Asteraceae) family. J Am Acad Dermatol 1980; 2:417-424.
21. Mitchell JC, Dupuis G, Towers HN. Allergic contact dermatitis from pyrethrum (Chrysanthemum spp.). The roles of pyrethrosin, a sesquiterpene lactone, and of pyrethrin II. Br J Dermatol 1972; 86:568-573.
22. Zucker A. Investigation of purified pyrethrum extracts. Ann Allergy 1965; 23:335-339.
23. Fisher A. A study to demonstrate a lack of cross-sensitivity to RID in ragweed sensitive patients. A draft of an unpublished paper included in Over-the-Counter (OTC) Volume 160227.
24. Feinberg SM. Pyrethrum sensitization. JAMA 1934; 102:1557-1558.
25. Barthel WF. Toxicity of pyrethrum and its constituents to mammals. In: Casida J, ed. Pyrethrum: The Natural Insecticide. New York: Academic Press; 1973:123-140.
26. Goncalo S. Contact sensitivity to lichens and compositae in Frullania dermatitis. Contact Dermatitis 1987; 16:84-86.
27. McCord CP, Kilker CH, Minster DK. Pyrethrum dermatitis. A record of the occurrence of occupational dermatoses among workers in the pyrethrum industry. JAMA 1921; 77:448-449.
28. Hausen BM, Schulz KH. Experimental studies on the identification of Chrysanthemum allergens. Contact Dermatitis 1975; 1:244-245.
29. Pevny I. Allergy to pesticides. Allergic contact eczema affliction of a vintner. Dermatosen Beruf Umwelt 1980; 28(6):186-189.
30. USEPA. Pyrethrins: 2nd Revised Occupational and Residential Exposure Assessment Recommendations for the Reregistration Eligibility Decision (RED) September 7, 2005.
31. Driver JH, Osimitz TG. "Pyrethrins: Non-Dietary (Residential) Risk Assessment." Submitted to the USEPA by the Pyrethrins Joint Venture; 2005.
32. Selim S. Human Exposure During and Following Use of a Pyrethrins/Piperonyl Butoxide/MGK-264 Shampoo Formulation on Dog. Submitted to the USEPA by the Non-Dietary Exposure Task force (NDETF); on July 22, 2005.
33. Felter SP, Ryan CA, Basketter DA, Gilmour NJ, G.F.G. Application of the risk assessment paradigm to the induction of allergic contact dermatitis. Regul Toxicol Pharmacol 2003; 37:1-10.
34. Benezra C, Sigman CC, Perry LR, Helmes CT, Maibach HI. A systematic search for structure-activity relationships of skin contact sensitizers: Methodology. J Invest Dermatol 1985; 85:351-356.
35. Sulzberger MB, Weinberg CB. Dermatitis due to insect powder. JAMA 1930; 95:111-113.
36. Kesten B, Laszlo E. Dermatitis due to sensitization to contact substances. Arch Derm Syphilol 1931; 23:221-237.
37. Brunsting LA, Anderson CR. Ragweed dermatitis: A report based on eighteen cases. JAMA 1984; 103:1285-1293.
38. Schwartz. Dermatitis Due to Pyrethrum Contained in an Insecticide: Public Health Report. 1934; 215:51-54.
39. Sweitzer SE, Tedder JW. Pyrethrum treatment of scabies. Med Lit 1935; 793-795.
40. Sequeira JH. Pyrethrum dermatitis. Br J Dermatol Syphil 1936; 48:473-476.
41. Sweitzer SE. Scabies: Further observations on its treatment with pyrethrum ointment. Lancet 1936; 56:467-468.
42. Martin JT, Hester K. Dermatitis caused by insecticidal pyrethrum flowers (Chrysanthemum cinerariifolium). Br J Dermatol Syphil 1941; 53:127-142.
43. Lord K, Johnson C. The production of dermatitis pyrethrum and attempts to produce a non-irritant extract. Br J Dermatol Syphil 1947; 59:367-375.
44. Baer RL, Ramsey D, Biondi E. The most common contact allergens 1968-1970. Arch Dermatol 1973; 108:74-78.
45. Burry JN, Kuchel R, Reid JG, Kirk J. Australian bush dermatitis: Compositae dermatitis in South Australia. Med J Aust 1973; 1:110-116.
46. Szarmach H, Ponieckca H. Alergia kontaktowa w rolnictwe. Przeglad Dermatologiczny 1973; 60:479-484.
47. Verhagen ARHB. Contact dermatitis in Kenya. Trans St Johns Hospit Dermatol Soc 1974; 60:86-90.
48. Schulz KH, Hausen BM, Wallhofer L, Schmidt-Loffler P. Chrysanthemum allergy. Pt II: Experimental studies on the causative agents. Arch Dermatol Forsch 1975; 251:235-244.
49. Shnaps Y, Gross M, Trau H. Erythema multiforme due to pyrethrum. Clin Pediatr 1981; 20:468.
50. Clarke J. Letter to the editor. Pediatr Emerg Care 1986; 2:65.
51. Lisi P, Caraffini S, Assalve D. Irritation and sensitization potential of pesticides. Contact Dermatitis 1987; 17:212-218.
52. Goncalo M, Couto J, Goncalo S. Allergic contact dermatitis from Nicotiana tabacum. Contact Dermatitis 1990; 22:188-189.
53. Paulsen E, Andersen KE, Hausen BM. Compositae dermatitis in a Danish dermatology department in one year (I). Results of routine patch testing with the sesquiterpene lactone mix supplemented with aimed patch testing with extracts and sesquiterpene lactones of Compositae plants. Contact Dermatitis 1993; 29:6-10.
54. Gracia-Bravo B, Rodriguez-Pichardo A, Fernandez de Pierola S, Camacho F. Airborne erythema-multiforme-like eruption due to pyrethrum. Contact Dermatitis 1995; 33:443.
55. Goncalo S, Goncalo M, Sequeira J. Contact dermatitis to dendranthema morifolium ramat. Contact Dermatitis 1996; 35:3l0-311.
56. Lim HW, Cohen D, Soter NA. Chronic actimic dermatitis: Results of patch and photopatch tests with Compositae, fragrances, and pesticides. J Am Acad Dermatol 1998; 38:108-111.
57. Spettoli E, Silvani S, Lucente P, Guerra L, Vincenzi C. Contact dermatitis caused by sesquiterpene lactones. Am J Contact Dermat 1998; 9:49-50.
58. De Morais RM, Diogenes MJN, Veras OBV. Occupational contact dermatitis in fishermen of Cumbuco beach, Ceara, northeast Brazil. Contact Dermatitis 2000; 45:277-278.
59. Paulsen E, Andersen KE, Hausen BM. Sensitization and cross-reactions patterns in Danish Compositae-allergic patients. Contact Dermatitis 2001; 45:197-204.
60. Marrakchi S, Maibach HI. What is occupational contact dermatitis? An operational definition. Dermatol Clin 1994; 12:477-484.
61. Ale SL, Maibach HI. Clinical relevance in allergic contact dermatitis: An algorithmic approach. Dermatosen 1995; 43:119-121.