Anaplasmosis: Focusing on host-vector-pathogen interactions for vaccine development

Annals of the New York Academy of Sciences

Volumn 1078, Issue , 2006, Pages 416-423

  De La Fuente, José ^a,b   Ayoubi, Patricia ^a   Blouin, Edmour F ^a   Almazán, Consuelo ^a   Naranjo, Victoria ^b   Kocan, Katherine M ^a  

^a OKLAHOMA STATE UNIVERSITY   (United States)

^b INSTITUTO DE INVESTIGACIÓN EN RECURSOS CINEGÉTICOS IREC CSIC UCLM JCCM   (Spain)

Author keywords

Anaplasma marginale; Anaplasma phagocytophilum; RNA interference; Tick; Vaccine

Indexed keywords

ANAPLASMOSIS VACCINE; ANTIGEN; ANTIGEN 4D8;

ANAPLASMA MARGINALE; ANAPLASMA PHAGOCYTOPHILUM; ANAPLASMOSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; BACTERIAL VIRULENCE; CELL STRAIN HL 60; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE TRANSMISSION; DRUG MECHANISM; DRUG SYNTHESIS; EGG LAYING; EXPRESSED SEQUENCE TAG; GENE EXPRESSION; GENE SEQUENCE; HUMAN; HUMAN CELL; IMMUNIZATION; INFESTATION; LABORATORY TEST; MICROARRAY ANALYSIS; MOLTING; MOUSE; NONHUMAN; PATHOGENESIS; RNA INTERFERENCE; SCREENING;

ACARI; ANAPLASMA; ANAPLASMA MARGINALE; ANAPLASMA PHAGOCYTOPHILUM; BOS TAURUS; IXODIDA; RICKETTSIACEAE;

EID: 33845694286     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1374.081     Document Type: Conference Paper

References (24)

1. KOCAN, K.M., J. DE LA FUENTE, E.F. BEGUIN, et al. 2004. Anaplasma marginale (Rickettsiales: Anaplasmataceae): recent advances in defining host-pathogen adaptations of a tick-borne rickettsia. Parasitology 129: S285-S300.
2. DE LA FUENTE, J., R.B. MASSUNG, S.J. WONG, et al. 2005. Sequence analysis of the msp4 gene of Anaplasma phagocytophilum strains. J. Clin. Microbiol. 43: 1309-1317.
3. KOCAN, K.M., J. DE LA FUENTE, A.A. GUGLIELMONE & R.D. MELÉNDEZ. 2003. Antigens and alternatives for control of Anaplasma marginale infection in cattle. Clin. Microbiol. Rev. 16: 698-712.
4. DE LA FUENTE, J., A. LEW, H. LUTZ, et al. 2005. Genetic diversity of Anaplasma species major surface proteins and implications for anaplasmosis serodiagnosis and vaccine development. Anim. Health Res. Rev. 6: 75-89.
5. PALMER, G.H., F.R. RURANGIRWA, K.M. KOCAN & W.C. BROWN. 1999. Molecular basis for vaccine development against the ehrlichial pathogen Anaplasma marginale. Parasitol. Today 15: 253-300.
6. DE LA FUENTE, J., J.C. GARCÍA-GARCÍA, E.F. BLOUIN & K.M. KOCAN. 2001. Differential adhesion of major surface proteins 1a and 1b of the ehrlichial cattle pathogen Anaplasma marginale to bovine erythrocytes and tick cells. Int. J. Parasitol. 31: 145-153.
7. DE LA FUENTE, J., J.C. GARCIA-GARCIA, E.F. BLOUIN & K.M. KOCAN. 2003. Characterization of the functional domain of major surface protein 1a involved in adhesion of the rickettsia Anaplasma marginale to host cells. Vet. Microbiol. 91: 265-283.
8. DE LA FUENTE, J., J.C. GARCIA-GARCIA, E.F. BLOUIN, et al. 2001. Major surface protein la effects tick infection and transmission of Anaplasma marginale. Int. J. Parasitol. 31: 1705-1714.
9. GARCIA-GARCIA, J.C., J. DE LA FUENTE, E.F. BLOUIN, et al. 2004. Differential expression of the msp1α gene of Anaplasma marginale occurs in bovine erythrocytes and tick cells. Vet. Microbiol. 98: 261-272.
10. GARCIA-GARCIA, J.C., J. DE LA FUENTE, G. BELL, et al. 2004. Glycosylation of Anaplasma marginale major surface protein la and its putative role in adhesion to tick cells. Infect. Immun. 72: 3022-3030.
11. DE LA FUENTE, J., K.M. KOCAN, J.C. GARCIA-GARCIA, et al. 2003. Immunization against Anaplasma marginale major surface protein la reduces infectivity for ticks. J. Appl. Res. Vet. Med. 1: 285-292.
12. DE LA FUENTE, J., P. AYOUBI, E.F. BLOUIN, et al. 2005. Gene expression profiling of human promyelocytic cells in response to infection with Anaplasma phagocytophilum. Cell. Microbiol. 7: 549-559.
13. ALMAZÁN, C., K.M. KOCAN, D.K. BERGMAN, et al. 2003. Identification of protective antigens for the control of Ixodes scapularis infestations using cDNA expression library immunization. Vaccine 21: 1492-1501.
14. ALMAZÁN, C., K.M. KOCAN, D.K. BERGMAN, et al. 2003. Characterization of genes transcribed in an Ixodes scapularis cell line that were identified by expression library immunization and analysis of expressed sequence tags. Gene Ther. Mol. Biol. 7: 43-59.
15. ALMAZÁN, C., U. BLAS-MACHADO, K.M. KOCAN, et al. 2005. Characterization of three Ixodes scapularis cDNAs protective against tick infestations. Vaccine 23: 4403-4416.
16. DE LA FUENTE, J., C. ALMAZÁN, E.F. BLOUIN, et al. 2005. RNA interference screening in ticks for identification of protective antigens. Parasitol. Res. 96: 137-141.
17. MCGAREY, D.J., A.F. BARBET, G.H. PALMER, et al. 1994. Putative adhesins of Anaplasma marginale: major surface polypeptides 1a and 1b. Infect. Immun. 62: 4594-4601.
18. + T lymphocytes from calves immunized with Anaplasma marginale major surface protein 1 (MSP1), a heteromeric complex of MSP1a and MSP1b, preferentially recognize the MSP1a carboxyl terminus that is conserved among strains. Infect. Immun. 69: 6853-6862.
19. BROWN, W.C., T.C. MCGUIRE, W. MWANGI, et al. 2002. Major histocompatibility complex class II DR-restricted memory CD4(+) T lymphocytes recognize conserved immunodominant epitopes of Anaplasma marginale major surface protein 1a. Infect. Immun. 70: 5521-5532.
20. GARCIA-GARCIA, J.C., J. DE LA FUENTE, K.M. KOCAN, et al. 2004. Mapping of B-cell epitopes in the N-terminal repeated peptides of Anaplasma marginale major surface protein 1a and characterization of the humoral immune response of cattle immunized with recombinant and whole organism antigens. Vet. Immun. Immunopathol. 98: 137-151.
21. BLOUIN, E.F., J.T. SALIKI, J. DE LA FUENTE, et al. 2003. Antibodies to Anaplasma marginale major surface proteins 1a and 1b inhibit infectivity for cultured tick cells. Vet. Parasitol. 111: 247-260.
22. DE LA FUENTE, J., J.C. GARCIA-GARCIA, A.F. BARBET, et al. 2004. Adhesion of outer membrane proteins containing tandem repeats of Anaplasma and Ehrlichia species (Rickettsiales: Anaplasmataceae) to tick cells. Vet. Microbiol. 98: 313-322.
23. DE LA FUENTE, J. & K.M. KOCAN. 2003. Advances in the identification and characterization of protective antigens for development of recombinant vaccines against tick infestations. Expert Rev. Vaccines 2: 583-593.
24. DE LA FUENTE, J. & K. KOCAN. 2006. Strategies for development of vaccines for control of ixodid tick species. Parasite Immunol. 28: 275-283.