Allergic contact dermatitis due to β-blockers in eye drops: A retrospective analysis of multicentre surveillance data 1993-2004

Acta Dermato-Venereologica

Volumn 86, Issue 6, 2006, Pages 509-514

  Jappe, Uta ^a   Uter, Wolfgang ^b   Menezes De Pádua, Cristiane A ^b   Herbst, Rudolf A ^c   Schnuch, Axel ^d  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c INSTITUTE OF PATHOLOGY   (Germany)

^d UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

blocker; Allergic contact dermatitis; Cross reaction; Eye drops; Eyelid dermatitis; Glaucoma; Own medicaments

Indexed keywords

ANTIGLAUCOMA AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; EYE DROPS; LEVOBUNOLOL; METIPRANOLOL; TIMOLOL;

ARTICLE; CONTACT ALLERGY; CONTROLLED STUDY; CROSS REACTION; FEMALE; GERMANY; HUMAN; MAJOR CLINICAL STUDY; MALE; PATCH TEST; PRESCRIPTION; PRIORITY JOURNAL; SKIN ALLERGY;

ADRENERGIC BETA-ANTAGONISTS; ADULT; ADVERSE DRUG REACTION REPORTING SYSTEMS; DERMATITIS, ALLERGIC CONTACT; EUROPE; FEMALE; GLAUCOMA; HUMANS; MALE; MOLECULAR STRUCTURE; OPHTHALMIC SOLUTIONS; PATCH TESTS; RETROSPECTIVE STUDIES;

EID: 33845682137     PISSN: 00015555     EISSN: None     Source Type: Journal    
DOI: 10.2340/00015555-0162     Document Type: Article

References (33)

1. Herbst AR, Maibach IH. Contact dermatitis caused by allergy to ophthalmic drugs and contact lens solutions. Contact Dermatitis 1991; 25: 305-312.
2. Jappe U, Niebrügge B, Gollnick H. Allergische Reaktionen am äußeren Auge. Teil I: Kontaktallergie (Typ IV-Reaktionen). Der Augenspiegel 1997; 5: 29-33.
3. Nelson WL, Fraunfelder FT, Sills JM, Arrowsmith JB, Kuritsky JN. Adverse respiratory and cardiovascular events attributed to timolol ophthalmic solution, 1978-1985. Am J Ophthalmol 1986; 102: 606-611.
4. Faunfelder FT. Ocular beta-blockers and systemic effects. Arch Intern Med 1986; 146: 1073-1074.
5. Tosti A, Tosti G. Allergic contact conjunctivitis due to ophthalmic solution. In: Frosch PJ, Dooms-Goossens A, Lachapelle JM, Rycroft RJG, Scheper RJ, eds. Current topics in contact dermatitis. Berlin: Springer-Verlag, 1989: p. 269-272.
6. Katz IM. Beta blockers and the eye: an overview. Ann Ophthalm 1978, 10: 847-850.
7. Fernandez Vozmediano JM, Blasi NA, Romero Cabrera MA, Carrascosa Cerquero A. Allergic contact dermatitis to timolol. Contact Dermatitis 1986; 14: 252.
8. Romaguera C, Grimalt F, Vilaplana J. Contact dermatitis by timolol. Contact Dermatitis 1986; 14: 248.
9. Cameli N, Vicenzi C, Tosti A. Allergic contact conjunctivitis due to timolol in eyedrops. Contact Dermatitis 1991; 25: 129-130.
10. der Meeren HLM van, Meurs PJ. Sensitization to levobunolol eyedrops. Contact Dermatitis 1993; 28: 41-12.
11. Van Joost T, Middelkamp Hup J, Ros FE. Dermatitis as a side effect of long-term topical treatment with certain beta-blocking agents. Br J Dermatol 1979; 101: 171-176.
12. DeGroot AC, Conemans J. Contact allergy to metipranolol. Contact Dermatitis 1988; 18: 107-108.
13. Gailhofer G, Ludvan M. Beta-blockers: sensitizers in periorbital allergic contact dermatitis. Contact Dermatitis 1990; 23: 262.
14. Corazza M, Virgili A, Mantovani L, Masieri LT. Allergic contact dermatitis from cross-reacting beta-blocking agents. Contact Dermatitis 1993; 28: 188-189.
15. O'Donnell BF, Foulds IS. Contact allergy to beta-blocking agents in ophthalmic preparations. Contact Dermatitis 1993; 28: 121-122.
16. Zucchelli V, Silvani S, Vezzani C, Lorenzi S, Tosti A. Contact dermatitis from levobunolol and befunolol. Contact Dermatitis 1995; 33: 66-67.
17. Förster W. Allergisches Kontaktekzem auf Levobunolol und Timolol in der Glaukombehandlung. Derm 1997; 3: 130-131.
18. Quiralte J, Florido F, de-San-Pedro BS. Allergic contact dermatitis from carteolol and timolol in eyedrops. Contact Dermatitis 2000; 42: 245.
19. Nino M, Suppa F, Ayala F, Balato N. Allergic contact dermatitis due to the beta-blocker befunolol in eyedrops, with cross-sensitivity to carteolol. Contact Dermatitis 2001; 44: 369.
20. Uter W, Schnuch A, Geier J, Frosch PJ. The epidemiology of contact dermatitis - the Information Network of Departments of Dermatology (IVDK) in Germany. Eur J Dermatol 1998; 8: 36-40.
21. Wahlberg JE. Patch Testing. In: Rycroft RJG, Menné T, Frosch PJ, Lepoittevin J-P. eds. Textbook of contact dermatitis, 3rd edn. Berlin: Springer, 2001: p. 435-468.
22. Schnuch A, Aberer W, Agathos M, Brasch J, Frosch PJ, Fuchs Th, Richter G für die Deutsche Kontaktallergie-Gruppe. Leitlinien der Deutschen Dermatologischen Gesellschaft (DDG) zur Durchführung des Epikutantests mit Kontaktallergenen. Hautarzt 2001; 52: 864-866.
23. Schnuch A, Geier J, Uter W, Frosch PF, Lehmacher W, Aberer W, et al. National rates and regional differences in sensitization to allergens of the standard series. Population adjusted frequencies of sensitization (PAFS) in 40,000 patients from a multicentre study (IVDK). Contact Dermatitis 1997; 37: 200-209.
24. Uter W, Schnuch A, Gefeller O. Guidelines for the descriptive presentation and statistical analysis of contact allergy data. Contact Dermatitis 2004; 51: 47-56.
25. Anonymus. Rote Liste 2004. ECV: Aulendorf, 2004.
26. Schwabe U, Paffrath D. Arzneiverordnungs-Report 2004. Berlin: Springer, 2004.
27. Sanchez-Perez J, Del Rio MJ, Fernandez-Villalta MJ, Garcia-Diez A. Positive use test in contact dermatitis from betaxolol hydrochloride. Contact Dermatitis 2002; 46; 313-314.
28. Uter W, Balzer C, Geier J, Frosch PJ, Schnuch A. Patch testing with patients' own cosmetics and toiletries - results of the IVDK, 1998-2002. Contact Dermatitis 2005; 53: 226-233.
29. Herbst RA, Uter W, Pirker C, Geier J, Frosch PJ. Allergic and non-allergic periorbital dermatitis: patch test results of the Information Network of the Departments of Dermatology during a 5-year period. Contact Dermatitis 2004; 51: 13-19.
30. Koch P. Allergic contact dermatitis due to timolol and levobunolol in eyedrops, with no cross-sensitivity to other ophthalmic beta-blockers. Contact Dermatitis 1995; 33: 140-141.
31. Fedele R, Ricciardi L, Mazzeo L, Isola S. Allergic contact dermatitis to nebivolol. Allergy 2002; 57: 864-865.
32. Schnuch A, Uter W, Geier J, Gefeller O. Epidemiology of contact allergy: an estimation of morbidity employing the clinical epidemiology and drug-utilization research (CEDUR) approach. Contact Dermatitis 2002; 47: 32-39.
33. Schnuch A, Gefeller O, Uter W. Eine heimtückische und häufige Nebenwirkung: Das Ekzemtherapeutikum Bufexamac verursacht Kontaktallergien. Ergebnisse des IVDK. Dtsch Med Wochenschr 2005; 130: 2881-2886.