Both GnRH agonist and continuous oral progestin treatments reduce the expression of the tyrosine kinase receptor B and mu-opioid receptor in deep infiltrating endometriosis

Human Reproduction

Volumn 22, Issue 1, 2007, Pages 124-128

  Matsuzaki, S ^a   Canis, M ^a   Pouly, J L ^a   Botchorishvili, R ^a   Dechelotte P J ^b   Mage, G ^a  

^a HÔTEL DIEU   (France)

^b Departament de Anatomie et Cytologie Pathologiques   (France)

Author keywords

Deep infiltrating endometriosis; Endometriosis associated pain; Laser capture microdissection

Indexed keywords

GESTAGEN; GONADORELIN AGONIST; MESSENGER RNA; MU OPIATE RECEPTOR; SEROTONIN TRANSPORTER; TYROSINE KINASE RECEPTOR;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOMETRIOSIS; EPITHELIUM CELL; FEMALE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE IDENTIFICATION; GENETIC CODE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; LASER CAPTURE MICRODISSECTION; PAIN; PREOPERATIVE TREATMENT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STROMA CELL;

EID: 33845681716     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/del368     Document Type: Article

References (31)

1. Anaf V, Simon P, El Nakadi I, Fayt I, Buxant F, Simonart T, Peny MO and Noel JC (2000) Relationship between endometriotic foci and nerves in rectovaginal endometriotic nodules. Hum Reprod 15,1744-1750.
2. Borner C, Kraus J, Schroder H, Ammer H and Hollt V (2004) Transcriptional regulation of the human mu-opioid receptor gene by interleukin-6. Mol Pharmacol 66,1719-1726.
3. D'Hooghe TM (2003) Immunomodulators and aromatase inhibitors: Are they the next generation of treatment for endometriosis? Curr Opin Obstet Gynecol 15,243-249.
4. Dalal R and Djakiew D (1997) Molecular characterization of neurotrophin expression and the corresponding tropomyosin receptor kinases (trks) in epithelial and stromal cells of the human prostate. Mol Cell Endocrinol 134,15-22.
5. Davis CJ and McMillan L (2003) Pain in endometriosis: Effectiveness of medical and surgical management. Curr Opin Obstet Gynecol 15,507-512.
6. Harada T, Iwabe T and Terakawa N (2001) Role of cytokines in endometriosis. Fertil Steril 76,1-10.
7. Horie S, Harada T, Mitsunari M, Taniguchi F, Iwabe T and Terakawa N (2005) Progesterone and progestational compounds attenuate tumor necrosis factor alpha-induced interleukin-8 production via nuclear factor kappaB inactivation in endometriotic stromal cells. Fertil Steril 83,1530-1535.
8. Iwabe T, Harada T, Sakamoto Y, Iba Y, Horie S, Mitsunari M and Terakawa N (2003) Gonadotropin-releasing hormone agonist treatment reduced serum interleukin-6 concentrations in patients with ovarian endometriomas. Fertil Steril 80,300-304.
9. Kennedy S, Bergqvist A, Chapron C, D'Hooghe T, Dunselman G, Greb R, Hummelshoj L, Prentice A, Saridogan E; on behalf of the ESHRE Special Interest Group for Endometriosis and Endometrium Guideline Development Group (2005) ESHRE guideline for the diagnosis and treatment of endometriosis. Hum Reprod 20,2698-2704.
10. Koninckx PR and Martin D (1994) Treatment of deeply infiltrating endometriosis. Curr Opin Obstet Gynecol 6,231-241.
11. Kraus J, Borner C, Giannini E and Hollt V (2003) The role of nuclear factor kappaB in tumor necrosis factor-regulated transcription of the human mu-opioid receptor gene. Mol Pharmacol 64,876-884.
12. Mannion RJ, Costigan M, Decosterd I, Amaya F, Ma QP, Holstege JC, Ji RR, Acheson A, Lindsay RM, Wilkinson GA et al. (1999) Neurotrophins: peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity. Proc Natl Acad Sci USA 96,9385-9390.
13. Matsuzaki S, Canis M, Vaurs-Barriere C, Pouly JL, Boespflug-Tanguy O, Penault-Llorca F, Dechelotte P, Dastugue B, Okamura K, Mage G. (2004) DNA microarray analysis of gene expression profiles in deep endometriosis using laser capture microdissection. Mol Hum Reprod 10,719-728.
14. Matsuzaki S, Canis M, Vaurs-Barriere C, Boespflug-Tanguy O, Dastugue B and Mage G (2005) DNA microarray analysis of gene expression in eutopic endometrium from patients with deep endometriosis using laser capture microdissection. Fertil Steril 84 (Suppl 2),1180-1190.
15. Muzii L, Marana R, Pedulla S, Catalano GF and Mancuso S (1997) Correlation between endometriosis-associated dysmenorrhea and the presence of typical or atypical lesions. Fertil Steril 68,19-22.
16. Noyes RW, Hertig AT and Rock J (1950) Dating the endometrial biopsy. Fertil Steril 1,3-5.
17. Oral E, Olive DL and Arici A (1996) The peritoneal environment in endometriosis. Hum Reprod Update 2,385-398.
18. Parker JD, Leondires M, Sinaii N, Premkumar A, Nieman LK and Stratton P (2006) Persistence of dysmenorrhea and nonmenstrual pain after optimal endometriosis surgery may indicate adenomyosis. Fertil Steril 86,711-715.
19. Pol O, Alameda F and Puig MM (2001) Inflammation enhances mu-opioid receptor transcription and expression in mice intestine. Mol Pharmacol 60,894-899.
20. Sakamoto Y, Harada T, Horie S, Iba Y, Taniguchi F, Yoshida S, Iwabe T and Terakawa N (2003) Tumor necrosis factor-alpha-induced interleukin-8 (IL-8) expression in endometriotic stromal cells, probably through nuclear factor-kappa B activation: Gonadotropin-releasing hormone agonist treatment reduced IL-8 expression. J Clin Endocrinol Metab 88,730-735.
21. Satoh M and Minami M (1995) Molecular pharmacology of the opioid receptors. Pharmacol Ther 68,343-364.
22. Schulte-Herbruggen O, Nassenstein C, Lommatzsch M, Quarcoo D, Renz H and Braun A (2005) Tumor necrosis factor-alpha and interleukin-6 regulate secretion of brain-derived neurotrophic factor in human monocytes. J Neuroimmunol 160,204-209.
23. Sidell N, Han SW and Parthasarathy S (2002) Regulation and modulation of abnormal immune responses in endometriosis. Ann NY Acad Sci 955,159-173.
24. Sommer C and Kress M (2004) Recent findings on how proinflammatory cytokines cause pain: Peripheral mechanisms in inflammatory and neuropathic hyperalgesia. Neurosci Lett 361,184-187.
25. Stein C, Hassan AH, Lehrberger K, Giefing J and Yassouridis A (1993) Local analgesic effect of endogenous opioid peptides. Lancet 342,321-324.
26. Stein C, Hassan AH, Przewlocki R, Gramsch C, Peter K and Herz A (1990) Opioids from immunocytes interact with receptors on sensory nerves to inhibit nociception in inflammation. Proc Natl Acad Sci USA 87,5935-5939.
27. Szabo I, Chen XH, Xin L, Adler MW, Howard OM, Oppenheim JJ and Rogers TJ (2002) Heterologous desensitization of opioid receptors by chemokines inhibits chemotaxis and enhances the perception of pain. Proc Natl Acad Sci USA 99,10276-10281.
28. Vercellini P, Trespidi L, De Giorgi O, Cortesi I, Parazzini F and Crosignani PG (1996) Endometriosis and pelvic pain: Relation to disease stage and localization. Fertil Steril 65,299-304.
29. Watkins LR, Maier SF and Goehler LE (1995) Immune activation: The role of pro-inflammatory cytokines in inflammation, illness responses and pathological pain states. Pain 63,289-302.
30. Zhang N, Rogers TJ, Caterina M and Oppenheim JJ (2004) Proinflammatory chemokines, such as C-C chemokine ligand 3, desensitize mu-opioid receptors on dorsal root ganglia neurons. J Immunol 173,594-599.
31. Zhao D, Lebovic DI and Taylor RN (2002) Long-term progestin treatment inhibits RANTES (regulated on activation, normal T cell expressed and secreted) gene expression in human endometrial stromal cells. J Clin Endocrinol Metab 87,2514-2519.