Assessment of angiogenesis expression and its relationship with prognosis of colorectal cancer by conventional and computer-assisted histopathological image analysis

Acta Cirurgica Brasileira

Volumn 21, Issue 6, 2006, Pages 392-397

  Leme, Marcelo Betim Paes ^a   Waitzberg, Ângela Flavia Logullo ^b   Neto, Ricardo Artigiani ^b   Linhares, Marcelo Moura ^b   Matos, Delcio ^b,c  

^a University Center of Volta Redonda   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c NONE   (Brazil)

Author keywords

Colonic Neoplasms; Computer Assisted; Image Processing; Prognosis

Indexed keywords

CD34 ANTIGEN;

ADULT; AGED; ANGIOGENESIS; ARTICLE; CANCER RELAPSE; CANCER STAGING; CANCER SURVIVAL; CLINICAL ASSESSMENT; COLORECTAL ADENOCARCINOMA; COLORECTAL CANCER; COMPUTER AIDED DESIGN; COMPUTER PROGRAM; CONTROLLED STUDY; CORRELATION COEFFICIENT; DENSITY; ENDOTHELIUM; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MICROVASCULATURE; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; QUANTITATIVE ANALYSIS; ADENOCARCINOMA; BRAZIL; COLORECTAL TUMOR; COMPUTER ASSISTED DIAGNOSIS; MIDDLE AGED; MORTALITY; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; RETROSPECTIVE STUDY; VASCULARIZATION;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; BRAZIL; COLORECTAL NEOPLASMS; FEMALE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MALE; MIDDLE AGED; NEOPLASM STAGING; NEOVASCULARIZATION, PATHOLOGIC; PROGNOSIS; RETROSPECTIVE STUDIES;

EID: 33845677262     PISSN: 01028650     EISSN: 16782674     Source Type: Journal    
DOI: 10.1590/s0102-86502006000600007     Document Type: Article

References (30)

1. Yu H-G, Zhong X, Yang Y-N, Luo H-S, Yu J-P, Meier J-J, Schrader H, Bastian A, Schmidt WE, Schimitz F. Increased expression of nuclear factor kBReIA is correlated with tumor angiogenesis in human colorectal cancer. Int J Colorectal Dis. 2004; 19:18-22.
2. Stoeltzing O, Wenbiau L, Reinmuth N, Parikh A, Ahmad SA, Jung YD, et al. Angiogenesis and antiangiogenic therapy of colon cancer liver metastasis. Ann Surg Oncol. 2003;10:722-33.
3. Frank RE, Saclarides TJ, Leurgans S, Speziale NJ, Drab EA, Rubin DB. Tumor angiogenesis as a predictor of recurrence and survival in pacientes with node-negative colon cancer. Ann Surg. 1995; 222:695-99.
4. Takebayashi Y, Akiyama S, Yamada K, Akiba S, Aikou T. Angiogenesis as an unfavorable prognostic factor in human colorectal carcinoma. Cancer. 1996; 78:226-31.
5. Vermeulen PB, Van Den Eynden GG, Huget P, Goovaerts G, Weyler J, Lardon F, et al. Prospective study of intratumoral microvessel density, p53 expression and survival in colorectal cancer. Br J Cancer. 1999; 79:316-22.
6. Sharma S, Sharma MC, Sarkar C. Morphology of angiogenesis in human cancer: a conceptual overview, histoprognostic perspective and significance of neoangiogenesis. Histopathology. 2005;46:481-9.
7. Sternfeld T, Foss HD, Kruschewski M, Runkel N. The prognostic significance of tumor vascularization in patients with localized colorectal cancer. Int J Colorectal Dis. 1999; 14:272-6.
8. Pietra N, Sarli L, Caruana P, Cabras A, Costi R, Gobbi S, et al. Is tumor angiogenesis a prognostic factor in patients with colorectal cancer and no involved nodes? Eur J Surg. 2000; 166:552-6.
9. Fox SB, Leek RD, Weekes MP, Whitehouse RM, Gatter KC, Harris AL. Quantitation and prognostic value of breast cancer angiogenesis: comparison of microvessel density, chalkley count and computer image analysis. J Pathol. 1995; 177:275-83.
10. Simpson JF, Ahn C, Battifora H, Esteban JM. Endothelial area as a prognostic indicator for invasive breast carcinoma. Cancer. 1996; 77:2077-85.
11. Tsuji T, Sasaki Y, Tanaka M, Hanabata N, Hada R, Munakata A. Microvessel morphology and vascular endothelial growth factor expression in human colonic carcinoma with or without metastasis. Lab Invest. 2002; 85:555-62.
12. Weidner N, Semple JP, Welch WR, Folkman J. Tumor angiogenesis and metastasis: correlation in invasive breast carcinoma. N Engl J Med. 1991; 324:1-8.
13. Vermeulen PB, Verhoeven D, Fierens H, Hubens G, Goovaerts G, Van Marck E, et al. Microvessel quantification in primary colorectal carcinoma: an immunohistochemical study. Br J Cancer. 1995; 71:340-3.
14. Novelli MG, Barreto E, Matos D, Saad SS, Borra RC. Aplicação do processamento de imagens por computador na quantificação das variáveis histopatologicas da reparação tecidual de anastomoses colocolicas em ratos. Rev Assoc Med Bras. 1997;43:277-82.
15. Vermeulen PB, Gasparini G, Fox SB, Toi M, Martins L, McCulloch P, et al. Quantification of angiogenesis in solid human tumours: an international consensus on the methodology and criteria of evaluation. Eur J Cancer. 1996; 32:2474-84.
16. Folkman J. What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst. 1990; 82:4-6.
17. Tomisaki SI, Ohno S, Ichiyoshi Y, Kuwano H, Maehara Y, Sugimachi K. Microvessel quantification and its possible relation with liver metastasis in colorectal cancer. Cancer. 1996; 77:1722-8.
18. Yamamura T, Tsukikawa S, Yamada K, Yamaguchi S. Morphologic analysis of microvessels in colorectal tumors with respect to the formation of liver metastases. J Surg Oncol. 2001; 78:259-64.
19. Kimura T, Tanaka S, Hurama K, Sumii K, Kajiyama G, Shimamoto F, et al. Clinical significance of MCU1 and E-cadherin expression, cellular proliferation and angiogenesis at the depeest invasive portion of colorectal cancer. Int J Oncol. 2000; 16:55-64.
20. Bossi P, Viale G, Lee AKC, Alfano RM, Coggi G, Bosari S. Angiogenesis in colorectal tumors: microvessel quantification in adenomas and carcinomas with clinicopathological correlations. Cancer Res. 1995; 55:5049-53.
21. Cianchi F, Palomba A, Messerini L, Boddi V, Asirelli G, Perigli G. Tumor angiogenesis in lymph node-negative rectal cancer: correlation with clinicopathological parameters and prognosis. Ann Surg Oncol. 2002; 9:20-6.
22. Nanni O, Volpi A, Frassineti GK, De Paola F, Granato AM, Dubini A, et al. Role of biological markers in the clinical outcome of colon cancer. Br J Cancer. 2002; 87:868-75.
23. Kim NT, Elie N, Plancoulaine B, Herlin P, Coster M. Original approach for quantification of blood vessels on the whole tumour section. An Cell Pathol. 2003; 25:63-75.
24. Lee JS, Jung JJ, Kim J. Quantification of angiogenesis by a computerized image analysis in renal cell carcinoma. An Quant Cytol Histol. 2000; 22:469-74.
25. Olewniczak S, Cosía M, Kolodziej B, Kwas A, Kram A, Domagala W. Angiogenesis as determined by computerized image analysis and the risk of early relapse in women invasive ductal breast carcinoma. Pol J Pathol. 2003; 54:53-9.
26. Vlems F, Van der Worp E, Van der Laak J, Van de Velde C, Nagtegaal L, Van Krieken H. A study into methodology and application of quantification of tumour vasculature in rectal cancer. Virchows Arch. 2004; 445:263-70.
27. Guba M, Seeliger H, Kleespies A, Jauch Kw, And Bruns C. Vascular endothelial growth factor in colorectal cancer. Int J Colorectal Dis. 2004.
28. Giatromanolaki A, Stathopoulos GP, Tsiobanou E, Papadimitriou C, Georgoulias V, Gatter KC, et al Combined role of tumor angiogenesis, bcl-2, and p53 expression in the prognosis of patients with colorectal carcinoma. Cancer. 1999; 86:1421-30.
29. Axelsson K, Ljung BE, Moore DH, Thor AD, Chew KL, Edgerton SM et al Tumor angiogenesis as prognostic assay for invasive ductal breast carcinoma. J Natl Cancer Inst. 1995; 87:997-1008.
30. Vermeulen PB, Libura M, Libura J, O'Neil PJ, Van Dam P, Van Marck, et al. Influence of investigator experience and microscopic field size on microvessel density in node-negative breast carcinoma. Breast Cancer Res Treat. 1997; 42:165-72.