-
1
-
-
32944471170
-
N0147: A randomized phase III trial of oxaliplatin plus 5-fluorouracil/leucovorin with or without cetuximab after curative resection of stage III colon cancer
-
Alberts SR, Sinicrope FA, Grothey A (2005) N0147: a randomized phase III trial of oxaliplatin plus 5-fluorouracil/leucovorin with or without cetuximab after curative resection of stage III colon cancer. Clin Colorectal Cancer 5: 211-213
-
(2005)
Clin Colorectal Cancer
, vol.5
, pp. 211-213
-
-
Alberts, S.R.1
Sinicrope, F.A.2
Grothey, A.3
-
2
-
-
0033952011
-
alpha-fluoro-beta-alanine: Effects on the antitumor activity and toxicity of 5-fluorouracil
-
Cao S, Baccanari DP, Rustum YM, Davis ST, Tansik RL, Porter DJT, Spector T (2000) alpha-fluoro-beta-alanine: effects on the antitumor activity and toxicity of 5-fluorouracil. Biochem Pharmacol 59: 953-960
-
(2000)
Biochem Pharmacol
, vol.59
, pp. 953-960
-
-
Cao, S.1
Baccanari, D.P.2
Rustum, Y.M.3
Davis, S.T.4
Tansik, R.L.5
Porter, D.J.T.6
Spector, T.7
-
3
-
-
26944454064
-
Capecitabine and mitomycin C as third-line therapy for patients with metastatic colorectal cancer resistant to fluorouracil and irinotecan
-
Chong G, Dickson JLB, Cunningham D, Norman AR, Rao S, Hill ME, Price TJ, Oates J, Tebbutt N (2005) Capecitabine and mitomycin C as third-line therapy for patients with metastatic colorectal cancer resistant to fluorouracil and irinotecan. Br J Cancer 93: 510-514
-
(2005)
Br J Cancer
, vol.93
, pp. 510-514
-
-
Chong, G.1
Dickson, J.L.B.2
Cunningham, D.3
Norman, A.R.4
Rao, S.5
Hill, M.E.6
Price, T.J.7
Oates, J.8
Tebbutt, N.9
-
4
-
-
4143123301
-
Phase I and pharmacokinetic study of the oral fluoropyrimidine S-1 on a once-daily-for-28-day schedule on patients with advanced malignancies
-
Chu QS, Hammond LA, Schwarz G, Ochoa L, Rha SY, Denis L, Molpus K, Roedig B, Letrent SP, Damle B, DeCillis AP, Rowinsky EK (2004) Phase I and pharmacokinetic study of the oral fluoropyrimidine S-1 on a once-daily-for-28- day schedule on patients with advanced malignancies. Clin Cancer Res 10: 4913-4921
-
(2004)
Clin Cancer Res
, vol.10
, pp. 4913-4921
-
-
Chu, Q.S.1
Hammond, L.A.2
Schwarz, G.3
Ochoa, L.4
Rha, S.Y.5
Denis, L.6
Molpus, K.7
Roedig, B.8
Letrent, S.P.9
Damle, B.10
DeCillis, A.P.11
Rowinsky, E.K.12
-
5
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecanrefractory metastatic colorectal cancer
-
Cunningham D, Humblet Y, Siena S, Khayat D, Bleiberg H, Santoro A, Bets D, Mueser M, Harstrick A, Verslype C, Chau I, Van Cutsem E (2004) Cetuximab monotherapy and cetuximab plus irinotecan in irinotecanrefractory metastatic colorectal cancer. N Engl J Med 351: 337-345
-
(2004)
N Engl J Med
, vol.351
, pp. 337-345
-
-
Cunningham, D.1
Humblet, Y.2
Siena, S.3
Khayat, D.4
Bleiberg, H.5
Santoro, A.6
Bets, D.7
Mueser, M.8
Harstrick, A.9
Verslype, C.10
Chau, I.11
Van Cutsem, E.12
-
6
-
-
0033874892
-
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
-
De Gramont A, Figer A, Seymour M, Homerin M, Hmissi A, Cassidy J, Boni C, Cortes-Funes H, Cervantes A, Freyer C, Papamichael D, Le Bali N, Louvet C, Hendler D, de Braud F, Wilson C, Morvan F, Bonetti A (2000) Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 18: 2938-2947
-
(2000)
J Clin Oncol
, vol.18
, pp. 2938-2947
-
-
De Gramont, A.1
Figer, A.2
Seymour, M.3
Homerin, M.4
Hmissi, A.5
Cassidy, J.6
Boni, C.7
Cortes-Funes, H.8
Cervantes, A.9
Freyer, C.10
Papamichael, D.11
Le Bali, N.12
Louvet, C.13
Hendler, D.14
De Braud, F.15
Wilson, C.16
Morvan, F.17
Bonetti, A.18
-
7
-
-
0034712536
-
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicentre randomized trial
-
Douillard JY, Cunningham D, Roth AD, Navarro M, James RD, Karasek P, Jandik P, Iveson T, Carmichael J, Alakl M, Gruia G, Awad L, Rougier P (2000) Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomized trial. Lancet 355: 1041-1047
-
(2000)
Lancet
, vol.355
, pp. 1041-1047
-
-
Douillard, J.Y.1
Cunningham, D.2
Roth, A.D.3
Navarro, M.4
James, R.D.5
Karasek, P.6
Jandik, P.7
Iveson, T.8
Carmichael, J.9
Alakl, M.10
Gruia, G.11
Awad, L.12
Rougier, P.13
-
8
-
-
0028078635
-
Quality of life during chemotherapy in patients with symptomatic advanced colorectal cancer: The Nordic Gastrointestinal Tumor Adjuvant Therapy Group
-
Glimelius B, Hoffman K, Graf W, Pahlman L, Sjoden PO (1994) Quality of life during chemotherapy in patients with symptomatic advanced colorectal cancer: The Nordic Gastrointestinal Tumor Adjuvant Therapy Group. Cancer 73: 556-562
-
(1994)
Cancer
, vol.73
, pp. 556-562
-
-
Glimelius, B.1
Hoffman, K.2
Graf, W.3
Pahlman, L.4
Sjoden, P.O.5
-
9
-
-
21344437927
-
Capecitabine as third line therapy in patients with advanced colorectal cancer
-
Gubanski M, Naucler G, Almerud A, Lidestahl A, Lind PARM (2005) Capecitabine as third line therapy in patients with advanced colorectal cancer. Acta Oncologica 44: 236-239
-
(2005)
Acta Oncologica
, vol.44
, pp. 236-239
-
-
Gubanski, M.1
Naucler, G.2
Almerud, A.3
Lidestahl, A.4
Lind, P.A.R.M.5
-
10
-
-
2942662092
-
Phase II study of capecitabine in patients with fluorouracil-resistant metastatic colorectal carcinoma
-
Hoff PM, Pazdur R, Lassere Y, Carter S, Samid D, Polito D, Abbruzzese JL (2004) Phase II study of capecitabine in patients with fluorouracil-resistant metastatic colorectal carcinoma. J Clin Oncol 22: 2078-2083
-
(2004)
J Clin Oncol
, vol.22
, pp. 2078-2083
-
-
Hoff, P.M.1
Pazdur, R.2
Lassere, Y.3
Carter, S.4
Samid, D.5
Polito, D.6
Abbruzzese, J.L.7
-
11
-
-
33845631100
-
Prognostic factors influencing the recurrence pattern and survival rates in curatively resected colorectal cancer
-
Kim NK, Park JK, Lee KY, Yun SH, Sohn SK, Min JS (2002) Prognostic factors influencing the recurrence pattern and survival rates in curatively resected colorectal cancer. J Korean Surg Soc 62: 421-429
-
(2002)
J Korean Surg Soc
, vol.62
, pp. 421-429
-
-
Kim, N.K.1
Park, J.K.2
Lee, K.Y.3
Yun, S.H.4
Sohn, S.K.5
Min, J.S.6
-
12
-
-
26444540662
-
A phase I/II study of trimetrexate and capecitabine in patients with advanced refractory colorectal cancer
-
Matin K, Jacobs SA, Richards T, Wong MK, Earle M, Evans T, Troetschel M, Ferri W, Friedland D, Pinkerton R, Volkin R, Wieand S, Ramathan RK (2005) A phase I/II study of trimetrexate and capecitabine in patients with advanced refractory colorectal cancer. Am J Clin Oncol 28: 439-444
-
(2005)
Am J Clin Oncol
, vol.28
, pp. 439-444
-
-
Matin, K.1
Jacobs, S.A.2
Richards, T.3
Wong, M.K.4
Earle, M.5
Evans, T.6
Troetschel, M.7
Ferri, W.8
Friedland, D.9
Pinkerton, R.10
Volkin, R.11
Wieand, S.12
Ramathan, R.K.13
-
13
-
-
0034089123
-
Phase II study of S-1, a novel fluoropyrimidine derivative, in patients with metastatic colorectal carcinoma
-
Ohtsu A, Baba H, Sakata Y, Mitachi Y, Horikoshi N, Sugimachi K, Taguchi T (2000) Phase II study of S-1, a novel fluoropyrimidine derivative, in patients with metastatic colorectal carcinoma. Br J Cancer 83: 141-145
-
(2000)
Br J Cancer
, vol.83
, pp. 141-145
-
-
Ohtsu, A.1
Baba, H.2
Sakata, Y.3
Mitachi, Y.4
Horikoshi, N.5
Sugimachi, K.6
Taguchi, T.7
-
14
-
-
0034727063
-
Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer
-
Saltz LB, Cox JV, Blanke C, Rosen LS, Fehrenbacher L, Moore MJ, Maroun JA, Ackland SP, Locker PK, Pirotta N, Elfring GL, Miller LL (2000) Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. N Engl J Med 343: 905-914
-
(2000)
N Engl J Med
, vol.343
, pp. 905-914
-
-
Saltz, L.B.1
Cox, J.V.2
Blanke, C.3
Rosen, L.S.4
Fehrenbacher, L.5
Moore, M.J.6
Maroun, J.A.7
Ackland, S.P.8
Locker, P.K.9
Pirotta, N.10
Elfring, G.L.11
Miller, L.L.12
-
15
-
-
2142641698
-
Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
-
Saltz LB, Meropol NJ, Loehrer Sr PJ, Needle MN, Kopit J, Mayer RJ (2004) Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol 22: 1201-1208
-
(2004)
J Clin Oncol
, vol.22
, pp. 1201-1208
-
-
Saltz, L.B.1
Meropol, N.J.2
Loehrer Sr., P.J.3
Needle, M.N.4
Kopit, J.5
Mayer, R.J.6
-
16
-
-
2442674385
-
Phase II study of oral S-1 for treatment of metastatic colorectal carcinoma
-
Shirao K, Ohtsu A, Takada H, Mitachi Y, Hirakawa K, Horikoshi N, Okamura T, Hirata K, Saitoh S, Isomoto H, Satoh A (2004) Phase II study of oral S-1 for treatment of metastatic colorectal carcinoma. Cancer 100: 2355-2361
-
(2004)
Cancer
, vol.100
, pp. 2355-2361
-
-
Shirao, K.1
Ohtsu, A.2
Takada, H.3
Mitachi, Y.4
Hirakawa, K.5
Horikoshi, N.6
Okamura, T.7
Hirata, K.8
Saitoh, S.9
Isomoto, H.10
Satoh, A.11
-
17
-
-
9344248389
-
Antitumor activity of 1M tegafur-0.4M 5-chloro-2,4-dihydropyridine-1M potassium oxonate (S-1) against human colon carcinoma orthotopically implanted into nude rats
-
Shirasaka T, Nakano K, Takechi T, Satake H, Uchida J, Fujioka A, Saito H, Okabe H, Oyama K, Takeda S, Unemi N, Fukushima M (1996) Antitumor activity of 1M tegafur-0.4M 5-chloro-2,4-dihydropyridine-1M potassium oxonate (S-1) against human colon carcinoma orthotopically implanted into nude rats. Cancer Res 56: 2602-2606
-
(1996)
Cancer Res
, vol.56
, pp. 2602-2606
-
-
Shirasaka, T.1
Nakano, K.2
Takechi, T.3
Satake, H.4
Uchida, J.5
Fujioka, A.6
Saito, H.7
Okabe, H.8
Oyama, K.9
Takeda, S.10
Unemi, N.11
Fukushima, M.12
-
18
-
-
0024536437
-
Optimal two-stage design for phase II clinical trials
-
Simon R (1989) Optimal two-stage design for phase II clinical trials. Controlled Clin Trials 10: 1-10
-
(1989)
Controlled Clin Trials
, vol.10
, pp. 1-10
-
-
Simon, R.1
-
19
-
-
0034766407
-
Complete response achieved following administration of S-1 in a patient with adrenal gland metastasis of 5-FU-resistant gastric cancer: A case report
-
Tsukioka Y, Matsumura Y, Hamaguchi T, Goto M, Muro K, Yamada Y, Shirao K (2001) Complete response achieved following administration of S-1 in a patient with adrenal gland metastasis of 5-FU-resistant gastric cancer: a case report. Jpn J Clin Oncol 31: 450-453
-
(2001)
Jpn J Clin Oncol
, vol.31
, pp. 450-453
-
-
Tsukioka, Y.1
Matsumura, Y.2
Hamaguchi, T.3
Goto, M.4
Muro, K.5
Yamada, Y.6
Shirao, K.7
-
20
-
-
33644840335
-
Adjuvant irinotecan regimens in combination with infusional 5-fluorouracil/leucovorin fail to improve outcomes in surgically resected colorectal cancer
-
Tyagi P (2005) Adjuvant irinotecan regimens in combination with infusional 5-fluorouracil/leucovorin fail to improve outcomes in surgically resected colorectal cancer. Clin Colorectal Cancer 5: 86-88
-
(2005)
Clin Colorectal Cancer
, vol.5
, pp. 86-88
-
-
Tyagi, P.1
-
21
-
-
0037430037
-
EORTC Early Clinical Studies Group early phase II trial of S-1 in patients with advanced or metastatic colorectal cancer
-
Van den Brande J, Schoffski P, Schellens JHM, Roth AD, Duffaud F, Weigang-Kohler K, Reinke F, Wanders J, de Boer RF, Vermorken JB, Fumoleau P (2003) EORTC Early Clinical Studies Group early phase II trial of S-1 in patients with advanced or metastatic colorectal cancer. Br J Cancer 88: 648-653
-
(2003)
Br J Cancer
, vol.88
, pp. 648-653
-
-
Van Den Brande, J.1
Schoffski, P.2
Schellens, J.H.M.3
Roth, A.D.4
Duffaud, F.5
Weigang-Kohler, K.6
Reinke, F.7
Wanders, J.8
De Boer, R.F.9
Vermorken, J.B.10
Fumoleau, P.11
|