Grey matter changes can improve the prediction of schizophrenia in subjects at high risk

BMC Medicine

Volumn 4, Issue , 2006, Pages

  Job, Dominic E ^a   Whalley, Heather C ^a   McIntosh, Andrew M ^a   Owens, David G C ^a   Johnstone, Eve C ^a   Lawrie, Stephen M ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CEREBELLUM; CLINICAL ASSESSMENT; COGNITION; DIAGNOSTIC VALUE; EARLY DIAGNOSIS; FAMILIAL DISEASE; FEMALE; GRAY MATTER; HIGH RISK PATIENT; HUMAN; IMAGE ANALYSIS; MAJOR CLINICAL STUDY; MALE; MORPHOMETRICS; NUCLEAR MAGNETIC RESONANCE IMAGING; PREDICTION; RISK ASSESSMENT; SCHIZOPHRENIA; TEMPORAL LOBE; VALIDATION PROCESS;

BRAIN; HUMANS; PREDICTIVE VALUE OF TESTS; RISK; SCHIZOPHRENIA; TEMPORAL LOBE;

EID: 33845660431     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/1741-7015-4-29     Document Type: Article

References (11)

1. Verdoux H, van Os J: Psychotic symptoms in non-clinical populations and the continuum of psychosis. Schizophr Res 2002, 54:59-65.
2. Klosterkotter J, Hellmich M, Steinmeyer EM, Schultze-Lutter F: Diagnosing schizophrenia in the initial prodromal phase. Arch Gen Psychiatry 2001, 58:158-164.
3. Johnstone EC, Ebmeier KP, Miller P, Owens DG, Lawrie SM: Predicting schizophrenia: findings from the Edinburgh High-Risk Study. Br J Psychiatry 2005, 186:18-25.
4. Job DE, Whalley HC, Johnstone EC, Lawrie SM: Grey matter changes over time in high risk subjects developing schizophrenia. NeuroImage 2005, 25:1023-1030.
5. Wing JK, Cooper JE, Sartorius N: The Description and Classification of Psychiatric Symptoms. An Instruction Manual for the PSE and Catego Systems Cambridge, UK: Cambridge University Press; 1974.
6. Johnstone EC, Abukmeil SS, Byrne M, Clafferty R, Grant E, Hodges A, Lawrie SM, Owens DG: Edinburgh high risk study - findings after four years: demographic, attainment and psychopathological issues. Schizophr Res 2000, 46:1-15.
7. Ashburner J, Friston KJ: Voxel-based morphometry - the methods. NeuroImage 2000, 11:805-821.
8. Lawrie SM, Whalley HC, Kestelman JN, Abukmeil SS, Byrne M, Hodges A, Rimmington JE, Best JJ, Owens DG, Johnstone EC: Magnetic resonance imaging of brain in people at high risk of developing schizophrenia. Lancet 1999, 353:30-33.
9. Lawrie SM, Whalley HC, Abukmeil SS, Kestelman JN, Donnelly L, Miller P, Best JJ, Owens DG, Johnstone EC: Brain structure, genetic liability and psychotic symptoms in subjects at high risk of developing schizophrenia. Biol Psychiatry 2001, 49:811-823.
10. Whalley HC, Kestelman JN, Rimmington JE, Kelso A, Abukmeil SS, Best JJ, Johnstone EC, Lawrie SM: Methodological issues in volumetric magnetic resonance imaging of the brain in the Edinburgh High Risk Project. Psychiatry Res 1999, 91:31-44.
11. Lawrie SM, Whalley HC, Abukmeil SS, Kestelman JN, Miller P, Best JJ, Owens DG, Johnstone EC: Temporal lobe volume changes in people at high risk of schizophrenia with psychotic symptoms. Br J Psychiatry 2002, 181:138-143.