Merging genetic and environmental effects in the Iowa Adoption Studies: Focus on depression

Annals of Clinical Psychiatry

Volumn 18, Issue 4, 2006, Pages 219-222

  Philibert, Robert ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Environmental effects; Genetic; Iowa adoption studies; Major depressive disorder

Indexed keywords

ADOPTION; ADOPTIVE PARENT; ARTICLE; BEHAVIOR DISORDER; COHORT ANALYSIS; DEPRESSION; DNA POLYMORPHISM; ENVIRONMENTAL FACTOR; EXON; FEMALE; GENE AMPLIFICATION; GENE LOCUS; GENETIC ANALYSIS; HEREDITY; HUMAN; MAJOR DEPRESSION; MENTAL DISEASE; PARENT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RISK FACTOR; X CHROMOSOME;

ADOPTION; ALCOHOLISM; ANTISOCIAL PERSONALITY DISORDER; COHORT STUDIES; DEPRESSIVE DISORDER, MAJOR; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; IOWA; POLYMORPHISM, GENETIC; RECEPTORS, THYROID HORMONE; RISK FACTORS; SOCIAL ENVIRONMENT;

EID: 33845657670     PISSN: 10401237     EISSN: 15473325     Source Type: Journal    
DOI: 10.1080/10401230600948399     Document Type: Article

References (16)

1. Caspi A, Sugden K, Moffitt TE, Taylor A, Craig IW, Harrington H, McClay J, Mill J, Martin J, Braithwaite A, Poulton R: Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 2003; 301:386-389
2. Neumeister A: Tryptophan depletion, serotonin, and depression: where do we stand? Psychopharmacol Bull 2003; 37:99-115
3. Lesch KP, Bengel D, Heils A, Sabol SZ, Greenberg BD, Petri S, Benjamin J, Muller CR, Hamer DH, Murphy DL: Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 1996; 274:1527-1531
4. Yates W, Cadoret R, Troughton E: The Iowa Adoption Studies Methods and Results. In: LaBuda M, Grigorenko E, eds. On the way to individuality: Methodological Issues in Behavioral Genetics, Hauppauge, NY: Nova Science Publishers, 1998:95-125
5. Cadoret RJ, Winokur G, Langbehn D, Troughton E, Yates WR, Stewart MA: Depression spectrum disease, I: The role of gene-environment interaction. Am J Psychiatry 1996; 153:892-899
6. Philibert R, Caspers K, Langbehn D, Troughton E, Yucuis R, Sandhu H, Cadoret R: The association of a HOPA polymorphism with major depression and phobia. Comprehensive Psychiatry 2002; 43:404-410
7. Robins L, Helzer J, Cottler L, Goldign E: National Institute of Mental Health Diagonistic Interview Schedule. St. Louis: Washington University, Department of Psychiatry, 1989
8. Berger AM, Knutson JF, Mehm JG, Perkins KA: The self-report of punitive childhood experiences of young adults and adolescents. Child Abuse Negl 1988, 12:251-262
9. Bucholz KK, Cadoret R, Cloninger CR, Dinwiddie SH, Hesselbrock VM, Nurnberger JI, Jr., Reich T, Schmidt I, Schuckit MA: A new, semi-structured psychiatric interview for use in genetic linkage studies: A report on the reliability of the SSAGA. J Stud Alcohol 1994; 55:149-158
10. DeLisi LE, Smith AB, Razi K, Stewart J, Wang Z, Sandhu HK, Philibert RA: Investigation of a candidate gene for schizophrenia on Xq13 previously associated with mental retardation and hypothyroidism. Am J Med Gen 2000; 96:398-403
11. Fleiss JL: Statistical Methods for Rates and Proportions. 2nd ed. New York, NY: John Wiley & Sons, Inc., 1981
12. Philibert R, Caspers K, Langbehn D, Troughton EP, Yucuis R, Sandhu HK, Cadoret RJ: The association of a HOPA polymorphism with major depression and phobia. Compr Psychiatry 2002; 43:404-410
13. Philibert RA, Sandhu HK, Hutton AM, Wang Z, Arndt S, Andreasen NC, Crowe R, Wassink TH: Population-based association analyses of the HOPA12bp polymorphism for schizophrenia and hypothyroidism. Am J Med Gen 2001; 105:130-134
14. Edenberg HJ, Dick DM, Xuei X, Tian H, Almasy L, Bauer LO, Crowe RR, Goate A, Hesselbrock V, Jones K, Kwon J, Li TK, Nurnberger JI, Jr., O'Connor SJ, Reich T, Rice J, Schuckit MA, Porjesz B, Foroud T, Begleiter H: Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. Am J Hum Genet 2004; 74:705-714
15. Spinks R, Sandhu HK, Andreasen NC, Philibert RA: Association of the HOPA12bp allele with a large X-chromosome haplotype and positive symptom schizophrenia. Am J Med Genet 2004; 127B:20-27
16. Wang E, Ding YC, Flodman P, Kidd JR, Kidd KK, Grady DL, Ryder OA, Spence MA, Swanson JM, Moyzis RK: The Genetic Architecture of Selection at the Human Dopamine Receptor D4 (DRD4) Gene Locus. Am J Hum Genet 2004; 74:931-944