Immunohistochemical study of the expression of epidermal growth factor receptor in benign prostatic hypertrophy, prostatic intraepithelial neoplasia and prostatic carcinoma

Indian Journal of Pathology and Microbiology

Volumn 49, Issue 4, 2006, Pages 495-499

  Rana, Shveta ^a,b   Sen, Rajeev ^a   Kalra, Rajnish ^a   Arora, B ^a   Sharma, Puja ^a   Gahlawat, Sapna ^a  

^a POST GRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

^b NONE   (India)

Author keywords

EGFR; Immunohistochemistry; Prostate

Indexed keywords

BIOTIN; EPIDERMAL GROWTH FACTOR RECEPTOR; PEROXIDASE; STREPTAVIDIN;

ADULT; AGED; ARTICLE; BASAL CELL; CELL COUNT; CLINICAL ARTICLE; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; PROSTATE CARCINOMA; PROSTATE HYPERTROPHY; PROSTATIC INTRAEPITHELIAL NEOPLASIA; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

AGED; AGED, 80 AND OVER; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; PROSTATIC HYPERPLASIA; PROSTATIC INTRAEPITHELIAL NEOPLASIA; PROSTATIC NEOPLASMS; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 33845644985     PISSN: 03774929     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Goustin AS, Leof EB, Shipley GD, Moses HL. Growth factors and cancer. Cancer Res 1986; 46:1015-29.
2. Derynck R, Goeddel DV, Ullrich A, et al. Synthesis of messenger RNA's for transforming growth factor a and b and the epidermal growth factor receptor by human tumors. Cancer Res 1987; 47:707-12.
3. Fox SB, Persad RA, Coleman N, Day CA, Silcocks PB, Collins CC. Prognostic value of C-erb-2 and epidermal growth factor receptor in stage A1 (T1a) prostatic carcinoma. Br J Urol 1994; 74:214-20.
4. Maygarden SJ, Strom S, Ware JL. Localization of epidermal growth factor receptor by immunohistochemical methods in human prostatic carcinoma, prostatic intraepithelial neoplasia and benign hyperplasia. Arch Pathol Lab Med 1992; 116:269-73.
5. Ibrahim GK, Kerns BM, McDonald JA, et al. Differential Immunoreactivity of epidermal growth factor receptor in benign, dysplastic and malignant prostatic tissues. J Urol 1993; 149(1):170-73.
6. Mellon K, Thompson S, Charlton RG, et al. p 53, c-erb B-2 and the epidermal growth factor receptor in the benign and malignant prostate. J Urol 1992; 147:496-9.
7. Turkeri LN, Sakr WA, Wydes SM, Grignon DJ, Pontes JE, Macoska JA. Comparative analysis of epidermal growth factor receptor expression and protein product in benign, premalignant, and malignant prostatic tissue. Prostate 1994; 25:199-205.
8. Morris GL, Dodd JG. Epidermal growth factor receptor mRNA levels in human prostatic tumors and cells lines. J Urol 1990; 142:1272-4.
9. Stevens A, Wilson I. The haematoxylins and eosin. In: Bancroft JD, Stevens A, editors. Theory and Practice of Histological Techniques. 4th ed. London: Churchill Livingstone, 1996: 99-112.
10. Gleason DF. Histological grading of prostatic cancer- a perspective. Hum Pathol 1992; 23:273-9.
11. Mc Neal JR, Bostwick DG. Intraductal dysplasia: A premalignant lesion of the prostate. Hum Pathol 1986; 17:64-71.
12. Myers RB, Kudlow JE, Grizzle WE. Expression of transforming growth factor-a , epidermal growth factor and the epidermal growth factor receptor in adenocarcinoma of the prostate and benign prostatic hyperplasia. Mod Pathol 1993; 6(6):733-7.
13. Cohen DW, Simak R, Fair WR, Melamed J, Scher HI, Cardo CC. Expression of transforming growth factor-a and the epidermal growth factor receptor in human prostate tissues. J Urol 1994; 152:2120-4.
14. Harper ME, Goddard L, Jones EG, Peeling WB, Griffiths. Epidermal Growth Factor Receptor expression by Northern Analysis and Immunohistochemistry in benign and malignant prostatic tumors. Eur J Cancer 1995; 31(9):1492-7.
15. Leav I, Mc Neal JE, Ziar J, Alroy J. The localization of transforming growth factor alpha and epidermal growth factor receptor in stromal and epithelial compartments of developing human prostate and hyperplastic, dysplastic and carcinomatous lesions. Hum Path 1998; 29:668-75.
16. Giri DK, Pal R, Wadhwa SN, Talwar CP. Immunohistochemical localization of transforming growth factor-a, epidermal growth factor receptor and c-erbB-2 protein in hyperplastic human prostates. Carcinogenesis 1995; 16(4):729-33.
17. Harper ME, Jones EG, Goddard L, Mathews P, Nicholson RI. Expression of androgen receptor and growth factors in premalignant lesions of the prostate. J Path 1998; 186:169-77.
18. Olapade Olaopa Eo, Moscatello DK, Mac Kay EH, Horsburgh T, Sandhu DPS, Terry TR et al. Evidence for the differential expression of variant EGF receptor protein in human prostate cancer. Br J Cancer 2000; 82(1):186-94.
19. Visakorpi T, Kallioniemi OP, Koivula T, Harvey J, Isola J. Expression of epidermal growth factor receptor and ERBB2 (HER-2/NeU) oncoprotein in prostatic carcinomas. Mod Pathol 1992; 5(6):643-8.