Role of sarcomere mechanics and Ca2+ overload in Ca2+ waves and arrhythmias in rat cardiac muscle

Annals of the New York Academy of Sciences

Volumn 1080, Issue , 2006, Pages 248-267

  Ter Keurs, Henk E D J ^a   Wakayama, Yuji ^b   Sugai, Yoshinao ^b   Price, Guy ^a   Kagaya, Yutaka ^b   Boyden, Penelope A ^c   Miura, Masahito ^b   Stuyvers, Bruno D M ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Arrhythmogenic; Ca2+ overload; Ca2+ waves; Shortening; SR

Indexed keywords

2,3 BUTANEDIONE; CALCIUM; TROPONIN C;

ANIMAL EXPERIMENT; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONFERENCE PAPER; CONTROLLED STUDY; ELECTROSTIMULATION; EXCITATION CONTRACTION COUPLING; HEART ARRHYTHMIA; HEART CONTRACTION; HEART MUSCLE; HEART VENTRICLE OVERLOAD; HYPOTHESIS; MECHANICS; MUSCLE RELAXATION; MUSCLE STRETCHING; MUSCLE TWITCH; MYOFILAMENT; NONHUMAN; RAT; SARCOMERE; SARCOMERE LENGTH; SARCOPLASMIC RETICULUM;

EID: 33845637186     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1380.020     Document Type: Conference Paper

References (52)

1. HUNTER, P.J., A.D. MCCULLOCH & H.E.D.J. TER KEURS. 1998. Modelling the mechanical properties of cardiac muscle. Prog. Biophys. Mol. Biol. 69: 289-331.
2. TER KEURS, H.E.D.J., Y. WAKAYAMA, et al. 2005. Role of sarcomere mechanics and Ca2+ overload in Ca2+ waves and arrhythmias in rat cardiac muscle. Ann. N. Y. Acad. Sci. 1047: 345-365.
3. HOUSMANS, P.R., N.K.M. LEE & J.R. BLINKS. 1983. Active shortening retards the decline of the intracellular calcium transient in mammalian heart muscle. Science 221: 159-161.
4. DANIEL, S.M.C.G., D. FEDIDA, C. LAMONT & H.E.D.J. TER KEURS. 1991. Role of the sarcolemma in triggered propagated contractions in rat cardiac trabeculae. Circ. Res. 68: 1408-1421.
5. MULDER, B.J.M., P.P. DE TOMBE & H.E.D.J. TER KEURS. 1989. Spontaneous and propagated contractions in rat cardiac trabeculae. J. Gen. Physiol. 93: 943-961.
6. DANIELS, M.C.G. & H.E.D.J. TER KEURS. 1990. Spontaneous contractions in rat cardiac trabeculae: trigger mechanism and propagation velocity. J. Gen. Physiol. 95: 1123-1137.
7. DANIELS, M.C.G. & H.E.D.J. TER KEURS. 1990. Propagated contractions in rat cardiac trabeculae: effects of caffeine, ryanodine, Bay K 8644, and D-600 [abstract]. Biophys. J. 57: 170a.
8. MIURA, M., P.A. BOYDEN & H.E.D.J. TER KEURS. 1999. Ca2+ waves during triggered propagated contractions in intact trabeculae. Determinants of the velocity of propagation. Circ. Res. 84: 1459-1468.
9. CHENG, H., W.J. LEDERER & M.B. CANNELL. 1993. Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle. Science 262: 740-744.
10. CANNELL, M.B., H. CHENG & W.J. LEDERER. 1994. Spatial nonuniformities in Cai during excitation contraction coupling in cardiac myocytes. Biophys. J. 67: 1942-1956.
11. LOPEZ-LOPEZ, J.R., P.S. SHACKLOCK & W.G. WIER. 1994. Local stochastic release of Ca2+ in voltage clamped rat heart cells: visualization with confocal microscopy. J. Physiol. 480: 21-29.
12. LOPEZ-LOPEZ, J.R., P.S. SHACKLOCK & W.G. WIER. 1995. Local Ca2+ transients triggered by single L type Ca2+ channel currents in cardiac cells. Science 268: 1042-1045.
13. CANNELL, M.B., H. CHENG & W.J. LEDERER. 1995. The control of calcium release in heart muscle. Science 268: 1045-1049.
14. WANG, S.-Q., L.-S. SONG, E.G. LAKATTA & H. CHENG. 2001. Ca2+ signalling between single L type Ca2+ channels and ryanodine receptors in heart cells. Nature 410: 592-596.
15. CHENG, H., M.R. LEDERER, W.J. LEDERER & M.B. CANNELL. 1996. Calcium sparks and [Ca++]i waves in cardiac myocytes. Am. J. Physiol. 270: C148-C159.
16. WIER, W.G., T.M. EGAN & J.R. LOPEZ-LOPEZ. 1994. Local control of excitation contraction coupling in rat heart cells. J. Physiol. 474: 463-471.
17. STERN, M.D., A.A. KORT, G.M. BHATNAGAR & E.G. LAKATTA. 1983. Scattered light intensity fluctuations in diastolic rat cardiac muscle caused by spontaneous calcium dependent cellular mechanical oscillations. J. Gen. Physiol. 82: 119-153.
18. WIER, W.G., M.B. CANNELL, J.R. BERLIN, et al. 1987. Cellular and subcellular heterogeneity of intracellular calcium concentration in single heart cells revealed by fura-2. Science 235: 325-328.
19. TAKAMATSU, T. & W.G. WIER. 1990. Calcium waves in mammalian heart: quantification of origin magnitude waveform and velocity. FASEB J. 4: 1519-1525.
20. FABIATO, A. & F. FABIATO. 1978. Calcium-induced release of calcium from the sarcoplasmic reticulum of skinned cells from adult human, dog, cat, rabbit, rat, and frog hearts and from fetal and new-born rat ventricles. Ann. N. Y. Acad. Sci. 307: 491-522.
21. FABIATO, A. 1985. Spontaneous versus triggered contractions of "calcium-tolerant" cardiac cells from the adult rat ventricle. Basic Res. Cardiol. 80: 83-88.
22. CAPOGROSSI, M.C. & E.G. LAKATTA. 1985. Frequency modulation and synchronization of spontaneous oscillations in cardiac cells. Am. J. Physiol. 248: H412-H418.
23. KORT, A.A. & E.G. LAKATTA. 1984. Calcium-dependent mechanical oscillations occur spontaneously in unstimulated mammalian cardiac tissues. Circ. Res. 54: 396-404.
24. OBAYASHI, M., B. XIAO, B.D. STUYVERS, et al. 2006. Spontaneous diastolic contractions and phosphorylation of the cardiac ryanodine receptor at serine-2808 in congestive heart failure in rat. Cardiovasc. Res. 69: 140-151.
25. ORCHARD, C.H., D.A. EISNER & D.G. ALLEN. 1983. Oscillations of intracellular calcium in mammalian cardiac muscle. Nature 304: 735-738.
26. WIER, W.G., M.B. CANNELL, et al. 1987. Cellular and subcellular heterogeneity of intracellular calcium concentration in single heart cells revealed by fura-2. Science 235: 325-328.
27. KASS, R.S., W.J. LEDERER, R.W. TSIEN & R. WEINGART. 1978. Role of calcium ions in transient inward currents and aftercontractions induced by strophanthidin in cardiac Purkinje fibres. J. Physiol. 281: 187-208.
28. ALLEN, D.G., D.A. EISNER & C.H. ORCHARD. 1984. Characterization of oscillations of intracellular calcium concentration in ferret ventricular muscle. J. Physiol. 352: 113-128.
29. MATSUDA, H., A. NOMA, Y. KURACHI & H. IRISAWA. 1982. Transient depolarization and spontaneous voltage fluctuations in isolated single cells from guinea-pig ventricles. Circ. Res. 51: 142-151.
30. BOYDEN, P.A., C. BARBHAYA, T. LEE & H.E.D.J. TER KEURS. 2003. Nonuniform Ca2+ transients and arrhythmogenic Purkinje cells that survive in the infarcted canine heart. Cardiovasc. Res. 57: 681-693.
31. BOYDEN, P.A., J. PU, J. PINTO & H.E.D.J. TER KEURS. 2000. Ca2+ transients and Ca2+ waves in purkinje cells: role in action potential initiation. Circ. Res. 86: 448-455.
32. 2+ waves during triggered propagated contractions in intact trabeculae. Am. J. Physiol. 274: H266-H276.
33. WAKAYAMA, Y., M. MIURA, B.D. STUYVERS, et al. 2005. Spatial nonuniformity of excitation-contraction coupling causes arrhythmogenic Ca2+ waves in rat cardiac muscle. Circ. Res. 96: 1266-1273.
34. TER KEURS, H.E.D.J., W.H. RIJNSBURGER, et al. 1980. Tension development and sarcomere length in rat cardiac trabeculae. Evidence of length-dependent activation. Circ. Res. 46: 703-714.
35. KONISHI, M., S. KURIHARA & T. SAKAI. 1984. The effects of caffeine on tension development and intracellular calcium transients in rat ventricular muscle. J. Physiol. 355: 605-618.
36. SITSAPESAN, R. & A.J. WILLIAMS. 1990. Mechanisms of caffeine activation of single calcium-release channels of sheep cardiac sarcoplasmic reticulum. J. Physiol. 423: 425-439.
37. SELLIN, L.C. & J.J. MCARDLE. 1994. Multiple effects of 2,3-butanedione monoxime. Pharmacol. Toxicol. 74: 305-313.
38. HERRMANN, C., J. WRAY, F. Travers & T. BARMAN. 1992. Effect of 2,3-butanedione monoxime on sarcoplasmic reticulum of saponin-treated rat cardiac muscle. Biochemistry 31: 12227-12232.
39. PHILLIPS, R.M. & R.A. ALTSCHULD. 1996. 2,3-butanedione 2-monoxime (BDM) induces calcium release from canine cardiac sarcoplasmic reticulum. Biochem. Biophys. Res. Commun. 229: 154-157.
40. BACKX, P.H.M., W.D. GAO, M.D. AZAN-BACKX & E. MARBAN. 1994. Mechanism of force inhibition by 2,3-butanedione monoxime in rat cardiac muscle: roles of [Ca++]i and cross-bridge kinetics. J. Physiol. 476: 487-500.
41. BACKX, P.H.M. & H.E.D.J. TER KEURS. 1993. Fluorescent properties of rat cardiac trabecule microinjected with fura-2 salt. Am. J. Physiol. 264: H1098-H1110.
42. GROUSELLE, M., B. STUYVERS, et al. 1991. Digital imaging microscopy analysis of calcium release from sarcoplasmic reticulum in single rat cardiac myocytes. Eur. J. Physiol. 418: 109-119.
43. MIURA, M., Y. WAKAYAMA, Y. SUGAI, et al. 2001. Effect of transient stretch on intracellular Ca2+ during triggered propagated contractions in intact trabeculae. Can. J. Physiol. Pharmacol. 79: 68-72.
44. JIANG, D., R. WANG, et al. 2005. Enhanced store overload-induced Ca2+ release and channel sensitivity to luminal Ca2+ activation are common defects of RyR2 mutations linked to ventricular tachycardia and sudden death. Circ. Res. 97: 1173-1181.
45. BACKX, P.H. & H.E.D.J. TER KEURS. 1993. Fluorescent properties of rat cardiac trabeculae microinjected with fura-2 salt. Am. J. Physiol. 264: H1098-H1110.
46. TER KEURS, H.E.D.J., Y. WAKAYAMA, M. MIURA, et al. 2006. Arrhythmogenic Ca(2+) release from cardiac myofilaments. Prog. Biophys. Mol. Biol. 90: 151-171.
47. Ter KEURS, H.E.D.J., Y. WAKAYAMA, M. MIURA, et al. 2005. Spatial nonuniformity of contraction causes arrhythmogenic Ca2+ waves in rat cardiac muscle. Ann. N. Y. Acad. Sci. 1047: 345-365.
48. WAKAYAMA, Y., Y. SUGAI, Y. KAGAYA, et al. 2001. Stretch and quick release of cardiac trabeculae accelerates Ca2+ waves and triggered propagated contractions. Am. J. Physiol. Circ. Physiol. 281: H2133-2142.
49. ALLEN, D.G. & J.C. KENTISH. 1985. The cellular basis of the length-tension relation in cardiac muscle. J. Mol. Cell. Cardiol. 17: 821-840.
50. CAPOGROSSI, M.C., M.D. STERN, H.A. SPURGEON & E.G. LAKATTA. 1988. Spontaneous calcium release from the sarcoplasmic reticulum limits calcium-dependent twitch potentiation in individual cardiac myocytes. J. Gen. Physiol. 91: 133-155.
51. DAVIDOFF, A.W., P.A. BOYDEN, et al. 2004. Spontaneous sarcomere activity in rat cardiac muscle: implications for force and rhythm of the failing heart. Ann. N. Y. Acad. Sci. 1015: 84-95.
52. ALLEN, D.G. & S. KURIHARA. 1982. The effects of muscle length on intracellular calcium transients in mammalian cardiac muscle. J. Physiol. 327: 79-94.