Molecular diagnosis and frequencies of primary hypolactasia in populations of Russia and neighboring countries

Molecular Biology

Volumn 40, Issue 6, 2006, Pages 931-935

  Borinskaya, S A ^a   Rebrikov, D V ^b   Nefedova, V V ^b   Kofiadi, I A ^b   Sokolova, M V ^a,c   Kolchina, E V ^d   Kulikova, E A ^e   Chernyshov, V N ^f   Kutsev, S I ^f   Polonikov, A V ^g   Ivanov, V P ^g   Kozlov, A I ^a,h   Yankovsky, N K ^a  

^a VAVILOV INSTITUTE OF GENERAL GENETICS   (Russian Federation)

^b DNK Tekhnologiya Ltd   (Russian Federation)

^c MOSCOW STATE UNIVERSITY   (Russian Federation)

^d Russian Ethnographical Museum   (Russian Federation)

^e Endocrinology Research Institute   (Russian Federation)

^f ROSTOV STATE MEDICAL UNIVERSITY   (Russian Federation)

^g KURSK STATE MEDICAL UNIVERSITY   (Russian Federation)

^h INSTITUTE OF DEVELOPMENTAL PHYSIOLOGY   (Russian Federation)

Author keywords

DNA diagnosis; Primary hypolactasia; Single nucleotide polymorphism

Indexed keywords

EID: 33845631884     PISSN: 00268933     EISSN: 16083245     Source Type: Journal    
DOI: 10.1134/S0026893306060124     Document Type: Article

References (25)

1. Kuokkanen M., Kokkonen J., Enattah N.S., Ylisaukko-Oja T., Komu H., Varilo T., Peltonen L., Savilahti E., Jarvela I. 2006. Mutations in the translated region of the lactase gene (LCT) underlie congenital lactase deficiency. Am. J. Hum. Genet. 78, 339-344.
2. Kozlov A.I. 1996. Gipolaktaziya: rasprostranennost', diagnostika, vrachebnaya taktika (Hypolactasia: Prevalence, Diagnosis, and Therapeutic Tactics). Moscow: ArktAn-S.
3. Kozlov A., Lisitsyn D. 1996. "The milk habit" (hypolactasia) in Finno-Ugrian peoples: A crossroad of physical anthropology, ethnology, and linguistics. Finnisch-Ugrische Mitteilungen. 18/19, 67-81.
4. Kozlov A.I., Balanovskaya E.V., Nurbaev S.D., Balanovskii O.P. 1998. Gene geography of primary hypolactasia in the Old World populations. Genetika. 34, 551-561.
5. Nose O., Iida Y., Kai H., Harada T., Ogawa M., Yabuuchi H. 1979. Breath hydrogen test for detecting lactose malabsorption in infants and children. Prevalence of lactose malabsorption in Japanese children and adults. Arch. Dis. Child. 54, 436-440.
6. Sahi T., Launiala K. 1978. Manifestation and occurrence of selective adult-type lactose malabsorption in Finnish teenagers: A follow-up study. Am. J. Digest. Dis. 23, 699-704.
7. Sekacheva M.I. 2002. The carbohydrate malabsorption syndrome in clinical practice. Klin. Persp. Gastroenterol. Gepatol. 1, 29-35.
8. Shleip T. 2004. Ostorozhno: laktoza! (Caution: Lactose). St. Petersburg: VES'.
9. Arola H. 1994. Diagnosis of hypolactasia and lactose malabsorption. Scand. J. Gastroenterol. 202, 26-35.
10. Jarvela I.E. 2005. Molecular diagnosis of adult-type hypolactasia (lactase non-persistence). Scand. J. Clin. Lab. Invest. 65, 535-539.
11. Harvey C.B., Fox M.F., Jeggo P.A., Mantei N., Povey S., Swallow D.M. 1993. Regional localization of the lactase-phlorizin hydrolase gene, LCT, to chromosome 2q21. Ann. Hum. Genet. 57, 179-185.
12. Enattah N.S., Sahi T., Savilahti E., Terwilliger J.D., Peltonen L., Jarvela I. 2002. Identification of a variant associated with adult-type hypolactasia. Nat. Genet. 30, 233-237.
13. Sokolova M.V., Borodina T.A., Gasemianrodsari F., Kozlov A.I., Grechanina E.Ya., Feshchenko S.P., Borinskaya S.A., Yankovsky N.K. 2005. Polymorphism of hypolactasia-associated locus C/T-13910 of the lactase gene LNO in Eastern Slavs and Iranians. Med. Genet. 11, 523-527.
14. Kuokkanen M., Enattah N.S., Oksanen A., Savilahti E., Orpana A., Jarvela I. 2003. Transcriptional regulation of the lactase-phlorizin hydrolase gene by polymorphisms associated with adult-type hypolactasia. Gut. 52, 647-652.
15. Nilsson T.K., Johansson C.A. 2004. A novel method for diagnosis of adult-type hypolactasia by genotyping of the -13910 C/T polymorphism with pyrosequencing technology. Scand. J. Gastroenterol. 3, 287-290.
16. Buning C., Ockenga J., Kruger S., Jurga J., Baier P., Dignass A., Vogel A., Strassburg C., Weltrich R., Genschel J., Lochs H., Schmidt H. 2003. The C/C(-13910) and G/G(-22018) genotypes for adult-type hypolactasia are not associated with inflammatory bowel disease. Scand. J. Gastroenterol. 38, 538-542.
17. Chao C.K., Sibley E. 2004. PCR-RFLP genotyping assay for a lactase persistence polymorphism upstream of the lactase-phlorizin hydrolase gene. Genet. Test. 8, 190-193.
18. Sambrook J., Fritsch E.F., Maniatis T. 1989. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, New York: Cold Spring Harbor Lab. Press.
19. Kofiadi I.A., Rabrikov D.V. 2006. Methods for detecting single-nucleotide polymorphisms: Allele-specific PCR and hybridization with an oligonucleotide probe. Genetika. 42, 22-32.
20. Kozlov A. 1995. The phenocline of primary hypolactasia in Finno-Ugrian populations. In: Papers on Anthropology. VI. Ed. Thetloff M. Tartu: Univ. Tartu, Centre of Physical Anthropology, pp. 111-115.
21. Gromashevskaya L.L., Genesh V.V., Bogachik N.A. 1991. Enzyme pathologies in healthy persons and patients with acute intestinal infections. In: Gopilaktaziia: klinicheskii i diagnosticheskii aspekty (Hypolactasia: Clinical and Diagnostic Aspects). Ed. Villako K. Tartu: Univ. Tartu, p. 66.
22. Socha J., Ksiazyk J., Flatz G., Flatz S.D. 1984. Prevalence of primary adult lactose malabsorption in Poland. Ann. Hum. Biol. 11, 311-316.
23. Tamulevichute D.I., Kalibatene D.Yu. 1987. On selective lactose malabsorbtion. Klin. Meditsina. 5, 73-75.
24. Gudmand-Hoyer E., Jarnum S. 1969. Lactose malabsorption in Greenland Eskimos. Acta Med. Scand. 86, 235-237.
25. Rahimi A.G., Delbruck H., Haeckel R., Goedde H.W., Flatz G. 1976. Persistence of high intestinal lactase activity (lactose tolerance) in Afghanistan. Hum. Genet. 34, 57-62.