Tocotrienols and α-tocopherol reduced acute and chronic lung lipid peroxidation induced by paraquat in rats

Pakistan Journal of Nutrition

Volumn 4, Issue 2, 2005, Pages 97-100

  Asmadi, A Y ^a   Adam, A ^b   Wan Ngah, W Z ^a   Norazlina, M ^a   Kamisah, Y ^a   Nur Azlina, M F ^a   Qodriyah, M S ^a   Ahmad, N S ^a   Gapor, M T ^c   Marzuki, A ^a  

^a UNIVERSITI KEBANGSAAN MALAYSIA   (Malaysia)

^b UNIVERSITI TEKNOLOGI MARA   (Malaysia)

^c MALAYSIAN PALM OIL BOARD   (Malaysia)

Author keywords

Lipid peroxidation; Lung; Paraquat; Rats; Tocotrienol; tocopherol

Indexed keywords

RATTUS;

EID: 33845630761     PISSN: 16805194     EISSN: None     Source Type: Journal    
DOI: 10.3923/pjn.2005.97.100     Document Type: Article

References (24)

1. Burton, G.W. 1994. Vitamin E: molecular and biological function. Proc. Nutr. Soc., 53: 251-262.
2. Bus, J.S. and J.E. Gibson, 1984. Paraquat: Model for ox id ant-initiated toxicity. Environ. Health Perspect., 55: 37-46.
3. Cheng, W.H., B.A. Valentine and X.G. Lei, 1999. High levels of dietary vitamin E do not replace cellular glutathione peroxidase in protecting mice from acute oxidative stress. J. Nutr., 129: 1951-1957.
4. Elsayed, N.M., M.G. Mustafa and J.F. Mead, 1990. Increased vitamin E content in the lung after ozone exposure: a possible mobilization in response to oxidative stress. Arch. Biochem. Biophys., 282: 263-269.
5. Fairus, S., M.N. Rosnah, H.M. Cheng and K. Sundram, 2004. Metabolic fate of palm tocotrienols in human postprandial plasma model. Asia Pac. J. Clin. Nutr., 13 (Suppľ): S77.
6. Greenberg, D.B., S.A. Lyons and J.A. Last, 1978. Paraquat-induced changes in the rate of collagen biosynthesis by rat lung explants. J. Lab. Clin. Med., 92: 1033-1042.
7. Hong, S.Y., D.H. Yang and K.Y. Hwang, 2000. Associations between laboratory parameters and outcome of paraquat poisoning. Toxicol. Lett., 118: 53-59.
8. Ikeda, K., Y. Kumagai, Y. Nagano, N. Matsuzawa and S. Kojo, 2003. Change in the concentration of vitamins C and E in rat tissues by paraquat administration. Biosci. Biotec. Biochem., 67: 1130- 1131.
9. Kamat, J.P. and T.P. Devasagayam, 1995. Tocotrienols from palm oil as potent inhibitors of lipid peroxidation and protein oxidation in rat brain mitochondria. Neurosci. Lett., 195: 179-182.
10. Kamat, J.P., H.D. Sarma, T.P. Devasagayam, K. Nesaretnam and Y. Basiron, 1997. Tocotrienols from palm oil as effective inhibitors of protein oxidation and lipid peroxidation in rat liver microsomes. Mol. Cell Biochem., 170: 131-137.
11. Kamisah, Y., A. Adam, W.Z. Wan Ngah, A. Gapor, B.A.K. Khalid and A. Marzuki, 2000. Tocotrienol and tocopherol were protective against xanthine plus xanthine oxidase induced oxidative stress. Asia Pac. J. Pharmacol., 14: 111-116.
12. Kappus, H., 1986. Overview of enzyme systems involved in bio-reduction of drugs and in redox cycling. Biochem. Pharmacol., 35: 1-6.
13. Koo, J.R., J.C. Kim, J.W. Yoon, G.H. Kim, R.W. Jeon, H.J. Kim, D.W. Chae and J.W. Noh, 2002. Failure of continuous venovenous hemofiltration to prevent death in paraquat poisoning. Am. J. Kidney Dis., 39: 55-59.
14. Ledwozyw, A., J. Michalak, A. Stepien and A. Kadziolka, 1986. The relationship between plasma triglycerides, cholesterol, total lipids and lipid peroxidation products during human atherosclerosis. Clin. Chim. Acta, 155: 275-284.
15. Margolis, A.M., S. Porasuphatana and G.M. Rosen, 2000. Role of paraquat in the coupling of nitric oxide synthase. Biochim. Biophys. Acta, 1524: 253- 257.
16. Melchiorri, D., R.J. Reiter, E. Sewerynek, M. Hara, L. Chen and G. Nistico, 1996. Paraquat toxicity and oxidative damage: Reduction by melatonin. Biochem. Pharmacol., 51: 1095-1099.
17. Mustafa, A., A.M. Gado, O.A. Al-Shabanah and A.M. Al- Bekairi, 2002. Protective effect of aminoguanidine against paraquat-induced oxidative stress in the lung of mice. Comp. Biochem. Physiol., 132: 391- 397.
18. Pearce, M.L., J. Yamashita and J. Beazell, 1965. Measurement of pulmonary edema. Circ. Res., 1965; 16: 482-8.
19. Rivero, C., E. Martinez, R. Martinez, E. Gonzalez, O.B. Espinoza and M.S. Ramirez, 1992. Paraquat poisoning in children: survival of three cases. Vet. Hum. Toxicol., 34: 164-165.
20. Smith, P. and D. Heath, 1976. Paraquat. Crit. Rev. Toxicol., 4: 411-445.
21. Soelaiman, I.N., N.S. Ahmad and B.A.K. Khalid, 2004. Palm oil tocotrienol mixture is better than alpha- tocopherol acetate in protecting bones against free-radical induced elevation of bone-resorbing cytokines. Asia Pac. J. Clin. Nutr., 13 (Suppl.): S111.
22. Suntres, Z.E. and P.N. Shek, 1996. Alleviation of paraquat-induced lung injury by pretreatment with bifunctional liposomes containing α-tocopherol and glutathione. Biochem. Pharmacol., 52: 1515- 1520.
23. Suntres, Z.E., 2002. Role of antioxidants in paraquat toxicity. Toxicol., 180: 65-77.
24. Tampo, Y., M. Tsukamoto and M. Yonaha, 1999. Superoxide production from paraquat evoked by exogenous NADPH in pulmonary endothelial cells. Free Radic. Biol. Med., 27: 588-595.