Afferent pathway and neuromodulation of superficial and deeper thoracic spinal neurons receiving noxious pulmonary inputs in rats

Autonomic Neuroscience: Basic and Clinical

Volumn 131, Issue 1-2, 2007, Pages 77-86

  Qin, Chao ^a   Foreman, Robert D ^a   Farber, Jay P ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

Inhaled ammonia; Pulmonary sympathetic afferents; Resiniferatoxin; Spinal cord; Vagus nerve

Indexed keywords

AMMONIA; PENTOBARBITAL; RESINIFERATOXIN; VANILLOID RECEPTOR 1;

ANIMAL EXPERIMENT; ARTICLE; ASSISTED VENTILATION; CONTROLLED STUDY; DESENSITIZATION; ELECTROSTIMULATION; MALE; NERVE CELL STIMULATION; NEUROMODULATION; NOCICEPTIVE STIMULATION; NONHUMAN; PARALYSIS; PRIORITY JOURNAL; RAT; SENSORY NERVE; THORACIC SPINAL CORD; VAGOTOMY;

ACTION POTENTIALS; AFFERENT PATHWAYS; AMMONIA; ANIMALS; LAMINECTOMY; LUNG; MALE; NEURAL INHIBITION; NEURONS, AFFERENT; RATS; RATS, SPRAGUE-DAWLEY; SACROCOCCYGEAL REGION; SPINAL CORD; STIMULATION, CHEMICAL; TIME FACTORS; VAGOTOMY;

EID: 33845617469     PISSN: 15660702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autneu.2006.07.007     Document Type: Article

References (47)

1. Capps J.A. An experimental study of the pain sense in the pleural membranes. Arch. Int. Med. 8 (1911) 717
2. Cervero F., and Connell L.A. Distribution of somatic and visceral primary afferent fibres within the thoracic spinal cord of the cat. J. Comp. Neurol. 230 (1984) 88-98
3. Chandler M.J., Zhang J., Qin C., and Foreman R.D. Spinal inhibitory effects of cardiopulmonary afferent inputs in monkeys: neuronal processing in high cervical segments. J. Neurophysiol. 87 (2002) 1290-1302
4. Coleridge H.M., and Coleridge J.C.G. Pulmonary reflexes: neural mechanisms of pulmonary defense. Annu. Rev. Physiol. 56 (1994) 69-91
5. Coon R.L., Clifford P.S., Hopp F.A., and Zuperku E.J. Reflex ventilatory effects of KCl stimulation of lung receptors with sympathetic afferents. Respir. Physiol. 82 (1990) 349-358
6. Dalsgaard C.J., and Lundberg J.M. Evidence for a spinal afferent innervation of the guinea pig lower respiratory tract as studied by the horseradish peroxidase technique. Neurosci. Lett. 45 (1984) 117-122
7. Dinh Q.T., Groneberg D.A., Peiser C., Mingomataj E., Joachim R.A., Witt C., Arck P.C., Klapp B.F., and Fischer A. Substance P expression in TRPV1 and trkA-positive dorsal root ganglion neurons innervating the mouse lung. Respir. Physiol. Neurobiol. 144 (2004) 15-24
8. Farber J.P., Qin C., and Foreman R.D. Afferent pathway and responses of thoracic neurons to irritation of lower airways in rats. Experimental Biology/IUPS 2005: Meeting Abstracts, #697.5 (2005) A1281
9. Foreman R.D. Integration of viscerosomatic sensory input at the spinal level. Prog. Brain Res. 122 (2000) 209-221
10. Gebhart G.F. Descending modulation of pain. Neurosci. Biobehav. Rev. 27 (2004) 729-737
11. Guz A. Respiratory sensations in man. Br. Med. Bull. 33 (1977) 175-177
12. Holmes R., and Torrance R.W. Afferent fibers of the stellate ganglion. Q. J. Exp. Physiol. 4427 (1959) 1-28
13. Hummel T., Sengupta J.N., Meller S.T., and Gebhart G.F. Responses of T2-4 spinal cord neurons to irritation of the lower airways in the rat. Am. J. Physiol. 273 (1997) R1147-R1157
14. Jackson C. Pain from the bronchi and lungs. A Res. Nerv. Ment. Dis. Proc. 23 (1943) 271
15. Karai L., Brown D.C., Mannes A.J., Connelly S.T., Brown J., Gandal M., Wellisch O.M., Neubert J.K., Olah Z., and Iadarola M.J. Deletion of vanilloid receptor 1-expressing primary afferent neurons for pain control. J. Clin. Invest. 113 (2004) 1344-1352
16. Kohl J., and Koller E.A. Stretch receptor activity during irritant-induced tachypnoea in the rabbit. Pflugers Arch. 386 (1980) 231-237
17. Kostreva D.R., Zuperku E.J., Hess G.L., Coon R.L., and Kampine J.P. Pulmonary afferent activity recorded from sympathetic nerves. J. Appl. Physiol. 39 (1975) 37-40
18. Kummer W., Fischer A., Kurkowski R., and Heym C. The sensory and sympathetic innervation of guinea-pig lung and trachea as studied by retrograde neuronal tracing and double-labelling immunohistochemistry. Neuroscience 49 (1992) 715-737
19. Lee L.Y., Shuei Lin Y., Gu Q., Chung E., and Ho C.Y. Functional morphology and physiological properties of bronchopulmonary C-fiber afferents. Anat. Rec. A Discov. Mol. Cell. Evol. Biol. 270 (2003) 17-24
20. Lu F., Qin C., Foreman R.D., and Farber J.P. Chemical activation of C1-C2 spinal neurons modulates intercostal and phrenic nerve activity in rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 286 (2004) R1069-R1076
21. Matsumoto S. Effects of ammonia and histamine on lung irritant receptors in the rabbit. Respir. Physiol. 77 (1989) 301-308
22. Miller K.E., Douglas V.D., Richards A.B., Chandler M.J., and Foreman R.D. Propriospinal neurons in the C1-C2 spinal segments project to the L5-S1 segments of the rat spinal cord. Brain Res. Bull. 47 (1998) 43-47
23. Molander C., Xu Q., Rivero-Melian C., and Grant G. Cytoarchitectonic organization of the spinal cord in the rat: II. The cervical and upper thoracic cord. J. Comp. Neurol. 289 (1989) 375-385
24. Morton D.R., Klassen K.P., and Curtis G.M. The clinical physiology of the human bronchi. I. Pain of tracheobronchial origin. Surgery 28 (1950) 699-704
25. Morton D.R., Klassen K.P., and Curtis G.M. The clinical physiology of the human bronchi. II. The effect of vagus section upon pain of tracheobronchial origin. Surgery 30 (1951) 800-809
26. Oh E.J., Mazzone S.B., Canning B.J., and Weinreich D. Reflex regulation of airway sympathetic nerves in guinea pigs. J. Physiol. 573 (2006) 549-564
27. Ossipov M.H., Bian D., Malan Jr. T.P., Lai J., and Porreca F. Lack of involvement of capsaicin-sensitive primary afferents in nerve-ligation injury induced tactile allodynia in rats. Pain 79 (1999) 127-133
28. Pan H.L., Khan G.M., Alloway K.D., and Chen S.R. Resiniferatoxin induces paradoxical changes in thermal and mechanical sensitivities in rats: mechanism of action. J. Neurosci. 23 (2003) 2911-2919
29. Plato M., Kummer W., and Haberberger R.V. Structural and neurochemical comparison of vagal and spinal afferent neurons projecting to the rat lung. Neurosci. Lett. 395 (2006) 215-219
30. Qin C., Chandler M.J., Miller K.E., and Foreman R.D. Chemical activation of cervical cell bodies: effects on responses to colorectal distension in lumbosacral spinal cord of rats. J. Neurophysiol. 82 (1999) 3423-3433
31. Qin C., Chandler M.J., and Foreman R.D. Afferent pathways and responses of T3-T4 spinal neurons to cervical and thoracic esophageal distensions in rats. Auton. Neurosci. 109 (2003) 10-20
32. Qin C., Chandler M.J., Miller K.E., and Foreman R.D. Chemical activation of cardiac receptors affects activity of superficial and deeper T3-T4 spinal neurons in rats. Brain Res. 959 (2003) 77-85
33. Qin C., Greenwood-Van Meerveld B., and Foreman R.D. Spinal neuronal responses to urinary bladder stimulation in rats with corticosterone or aldosterone onto the amygdala. J. Neurophysiol. 90 (2003) 2180-2189
34. Qin C., Kranenburg A., and Foreman R.D. Descending modulation of thoracic visceroreceptive transmission by C1-C2 spinal neurons. Auton. Neurosci. 114 (2004) 11-16
35. Rasmussen A.T. The pathways for nervous reflexes from the parenchyma of the lung. Am. Rev. Tuberc. 13 (1926) 545
36. Ruan T., Ho C.Y., and Kou Y.R. Afferent vagal pathways mediating respiratory reflexes evoked by ROS in the lungs of anesthetized rats. J. Appl. Physiol. 94 (2003) 1987-1998
37. Ruch T.C. Pathophysiology of pain. In: Ruch T.C., and Patton H.D. (Eds). Physiology and Biophysics (1961), Saunders, Philadelphia 345-363
38. Soukhova G., Wang Y., Ahmed M., Walker J.F., and Yu J. Bradykinin stimulates respiratory drive by activating pulmonary sympathetic afferents in the rabbit. J. Appl. Physiol. 95 (2003) 241-249
39. Soukhova-O'Hare G.K., Zhang J.W., Gozal D., and Yu J. Bradykinin B2 receptors mediate pulmonary sympathetic afferents induced reflexes in rabbits. Life Sci. 78 (2006) 1990-1997
40. Sugiura Y., Terui N., and Hosoya Y. Difference in distribution of central terminals between visceral and somatic unmyelinated (C) primary afferent fibers. J. Neurophysiol. 62 (1989) 834-840
41. Szallasi A., and Blumberg P.M. Resiniferatoxin, a phorbol-related diterpene, acts as an ultrapotent analog of capsaicin, the irritant constituent in red pepper. Neuroscience 30 (1989) 515-520
42. Szolcsanyi J., Szallasi A., Szallasi Z., Joo F., and Blumberg P.M. Resiniferatoxin: an ultrapotent selective modulator of capsaicin-sensitive primary afferent neurons. J. Pharmacol. Exp. Ther. 255 (1990) 923-928
43. Tanaka S., Barron K.W., Chandler M.J., Linderoth B., and Foreman R.D. Low intensity spinal cord stimulation may induce cutaneous vasodilation via CGRP release. Brain Res. 896 (2001) 183-187
44. Wang A.L., Blackford T.L., and Lee L.Y. Vagal bronchopulmonary C-fibers and acute ventilatory response to inhaled irritants. Respir. Physiol. 104 (1996) 231-239
45. Wang Y., Soukhova G., Proctor M., Walker J., and Yu J. Bradykinin causes hypotension by activating pulmonary sympathetic afferents in the rabbit. J. Appl. Physiol. 95 (2003) 233-240
46. Wu M., Komori N., Qin C., Farber J.P., Linderoth B., and Foreman R.D. Sensory fibers containing vanilloid receptor-1 (VR-1) mediate spinal cord stimulation-induced vasodilation. Brain Res. (2006) (Jul 10; Electronic publication ahead of print)
47. Zhang J., Chandler M.J., and Foreman R.D. Cardiopulmonary sympathetic and vagal afferents excite C1-C2 propriospinal cells in rats. Brain Res. 969 (2003) 53-58