The effect of buspirone on normal and hypoarousal-driven abnormal aggression in rats

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 31, Issue 1, 2007, Pages 27-31

  Haller, Jozsef ^a   Horváth, Zsuzsanna ^a   Bakos, Nikoletta ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

Abnormal; Aggression; Buspirone; Glucocorticoid; Hypoarousal; Serotonin

Indexed keywords

ANXIOLYTIC AGENT; BUSPIRONE; GLUCOCORTICOID; SEROTONIN;

AGGRESSION; ANIMAL EXPERIMENT; AROUSAL; ARTICLE; AUTONOMIC NERVOUS SYSTEM; BITE; CONDUCT DISORDER; CONFLICT; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; HORMONE DEFICIENCY; NONHUMAN; PSYCHOPATHY; RAT; SEROTONINERGIC TRANSMISSION;

ADRENALECTOMY; AGGRESSION; ANIMALS; ANTI-ANXIETY AGENTS; AROUSAL; BUSPIRONE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXPLORATORY BEHAVIOR; GLUCOCORTICOIDS; RATS; RATS, WISTAR; SOCIAL BEHAVIOR;

EID: 33845616673     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2006.05.022     Document Type: Article

References (57)

1. Bassarath L. Medication strategies in childhood aggression. Can J Psychiatry 48 (2003) 367-373
2. Biondi M., Picardi A., Pasquini P., Gaetano P., and Pancheri P. Dimensional psychopathology of depression: detection of an 'activation' dimension in unipolar depressed outpatients. J Affect Disord 84 (2005) 133-139
3. Blanchard R.J., and Blanchard D.C. The organization and modeling of animal aggression. In: Brain P.F., and Benton D. (Eds). The biology of aggression (1981), Sijthoff et Noordhoff, Alphen aan den Rijn 529-563
4. Bremner J.D., Vythilingam M., Vermetten E., Adil J., Khan S., Nazeer A., et al. Cortisol response to a cognitive stress challenge in posttraumatic stress disorder (PTSD) related to childhood abuse. Psychoneuroendocrinology 28 (2003) 733-750
5. Brennan P.A., Raine A., Schulsinger F., Kirkegaard-Sorensen L., Knop J., Hutchings B., et al. Psychophysiological protective factors for male subjects at high risk for criminal behavior. Am J Psychiatry 154 (1997) 853-855
6. Connor D.F., and Steingard R.J. A clinical approach to the pharmacotherapy of aggression in children and adolescents. Ann N Y Acad Sci 794 (1996) 290-307
7. 1B receptor agonists and aggression: a pharmacological challenge of the serotonin deficiency hypothesis. Eur J Pharmacol 526 (2005) 125-139
8. Dolan M., Anderson I.M., and Deakin J.F. Relationship between 5-HT function and impulsivity and aggression in male offenders with personality disorders. Br J Psychiatry 178 (2001) 352-359
9. Ekselius L., Tillfors M., Furmark T., and Fredrikson M. Personality disorders in the general population: DSM-IV and ICD_10 defined prevalence as related to sociodemographic profile. Pers Individ Differ 30 (2001) 311-320
10. Elzinga B.M., Schmahl C.G., Vermetten E., van Dyck R., and Bremner J.D. Higher cortisol levels following exposure to traumatic reminders in abuse-related PTSD. Neuropsychopharmacology 28 (2003) 1656-1665
11. Eronen M., Angermeyer M.C., and Schulze B. The psychiatric epidemiology of violent behaviour. Soc Psychiatry Psychiatr Epidemiol 33 (1998) S13-S23
12. Fava M., Voulo R.D., Wright E.C., Nierenberg A.A., Alpert J.E., and Rosenbaum J.F. Fenfluramine challenge in unipolar depression with and without anger attacks. Psychiatry Res 94 (2000) 9-18
13. Flint A.J., and van Reekum R. The pharmacologic treatment of Alzheimer's disease: a guide for the general psychiatrist. Can J Psychiatry 43 (1998) 689-697
14. Freo U., Holloway H.W., Kalogeras K., Rapoport S.I., and Soncrant T.T. Adrenalectomy or metyrapone-pretreatment abolishes cerebral metabolic responses to the serotonin agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) in the hippocampus. Brain Res 586 (1992) 256-264
15. Fuller R.W. Serotonin receptors involved in regulation of pituitary-adrenocortical function in rats. Behav Brain Res 73 (1996) 215-219
16. Halasz J., Liposits Z., Kruk M.R., and Haller J. Neural background of glucocorticoid dysfunction-induced abnormal aggression in rats: involvement of fear- and stress-related structures. Eur J Neurosci 15 (2002) 561-569
17. Haller J., Leveleki Cs., Halász J., and Baranyi J. The effect of glucocorticoids on the anxiolytic efficacy of buspirone. Psychopharmacology 157 (2001) 388-394
18. Haller J., Van De Schraaf J., and Kruk M.R. Deviant forms of aggression in glucocorticoid hyporeactive rats: a model for 'pathological' aggression?. J Neuroendocrinol 13 (2001) 102-107
19. Haller J., Halász J., Mikics E., and Kruk M.R. Chronic glucocorticoid deficiency-induced abnormal aggression, autonomic hypoarousal, and social deficit in rats. J Neuroendocrinol 16 (2004) 550-557
20. Haller J., Toth M., and Halasz J. The activation of raphe serotonergic neurons in normal and hypoarousal-driven aggression: a double labeling study in rats. Behav Brain Res 161 (2005) 88-94
21. Haller J., Mikics E., Halasz J., and Toth M. Mechanisms differentiating normal from abnormal aggression: glucocorticoids and serotonin. Eur J Pharmacol 526 (2005) 89-100
22. Harris G.T. The relationship between neuroleptic drug dose and the performance of psychiatric patients in a maximum security token economy program. J Behav Ther Exp Psychiatry 20 (1989) 57-67
23. Herpertz S.C., Werth U., Lukas G., Qunaibi M., Schuerkens A., Kunert H.J., et al. Emotion in criminal offenders with psychopathy and borderline personality disorder. Arch Gen Psychiatry 58 (2001) 737-745
24. Herrmann N. Recommendations for the management of behavioral and psychological symptoms of dementia. Can J Neurol Sci 28 Suppl 1 (2001) S96-S107
25. Jhanwar-Uniyal M., Renner K., Bailo M., Luine V.N., and Leibowitz S.F. Serotonin and 5-hydroxyindoleacetic acid levels in discrete hypothalamic areas of the rat brain: relation to circulating corticosterone. Neurosci Lett 79 (1987) 145-150
26. Kavoussi R., Armstead P., and Coccaro E. The neurobiology of impulsive aggression. Psychiatr Clin North Am 20 (1997) 395-403
27. Kazdin A.E. Treatments for aggressive and antisocial children. Child Adolesc Psychiatr Clin N Am 9 (2000) 841-858
28. Kunz M., Yates K.F., Czobor P., Rabinowitz S., Lindenmayer J.P., and Volavka J. Course of patients with histories of aggression and crime after discharge from a cognitive-behavioral program. Psychiatr Serv 55 (2004) 654-659
29. Kutcher S.P., Marton P., and Korenblum M. Relationship between psychiatric illness and conduct disorder in adolescents. Can J Psychiatry 34 (1989) 526-529
30. MacLennan K.M., Smith P.F., and Darlington C.L. Adrenalectomy-induced neuronal degeneration. Prog Neurobiol 54 (1998) 481-498
31. McBurnett K., Lahey B.B., Rathouz P.J., and Loeber R. Low salivary cortisol and persistent aggression in boys referred for disruptive behavior. Arch Gen Psychiatry 57 (2000) 38-43
32. Melamed S., Ugarten U., Shirom A., Kahana L., Lerman Y., and Froom F. Chronic burnout, somatic arousal and elevated salivary cortisol levels. J Psychosom Res 46 (1999) 591-598
33. Moran P. The epidemiology of antisocial personality disorder. Soc Psychiatry Psychiatr Epidemiol 34 (1999) 231-242
34. Mpofu E. Psychopharmacology in the treatment of conduct disorder children and adolescents: rationale, prospects, and ethics. S Afr J Psychol 32 (2002) 9-22
35. Nelson R.J., and Chiavegatto S. Molecular basis of aggression. Trends Neurosci 24 (2001) 713-719
36. Olvera R.L. Intermittent explosive disorder: epidemiology, diagnosis and management. CNS Drugs 16 (2002) 517-526
37. Pabis D.J., and Stanislav S.W. Pharmacotherapy of aggressive behavior. Ann Pharmacother 30 (1996) 278-287
38. Pajer K., Gardner W., Rubin R.T., Perel J., and Neal S. Decreased cortisol levels in adolescent girls with conduct disorder. Arch Gen Psychiatry 58 (2001) 297-302
39. Pine D.S., and Cohen E. Therapeutics of aggression in children. Paediatr Drugs 1 (1999) 183-197
40. 1A receptor agonists buspirone and gepirone attenuate apomorphine-induced aggressive behaviour in adult male Wistar rats. J Physiol Pharmacol 51 (2000) 833-846
41. Raine A. Autonomic nervous system factors underlying disinhibited, antisocial, and violent behaviour. Ann N Y Acad Sci 794 (1996) 46-59
42. Reeves R.R., Struve F.A., and Patrick G. Auditory and visual P300 evoked potentials do not predict response to valproate treatment of aggression in patients with borderline and antisocial personality disorders. Clin EEG Neurosci 36 (2005) 49-51
43. Reid W.H., and Gacono C. Treatment of antisocial personality, psychopathy, and other characterologic antisocial syndromes. Behav Sci Law 18 (2000) 647-662
44. Sareen J., Stein M.B., Cox B.J., and Hassard S.T. Understanding comorbidity of anxiety disorders with antisocial behavior: findings from two large comorbidity surveys. J Nerv Ment Dis 192 (2004) 178-186
45. Southwick S.M., Bremner J.D., Rasmusson A., Morgan III C.A., Arnsten A., and Charney D.S. Role of norepinephrine in the pathophysiology and treatment of posttraumatic stress disorder. Biol Psychiatry 46 (1999) 1192-1204
46. Stutzmann G.E., McEwen B.S., and LeDoux J.E. Serotonin modulation of sensory inputs to the lateral amygdala: dependency on corticosterone. J Neurosci 18 (1998) 9529-9538
47. Telegdy G., and Vermes I. Effect of adrenocortical hormones on activity of the serotoninergic system in limbic structures in rats. Neuroendocrinology 18 (1975) 16-26
48. Timmerman I.G., and Emmelkamp P.M. The effects of cognitive-behavioral treatment for forensic inpatients. Int J Offender Ther Comp Criminol 49 (2005) 590-606
49. Van de Kar L.D., and Blair M.L. Forebrain pathways mediating stress-induced hormone secretion. Front Neuroendocrinol 20 (1999) 1-48
50. van Goozen S.H., Matthys W., Cohen-Kettenis P.T., Gispen-de Wied C., Wiegant V.M., and van Engeland H. Salivary cortisol and cardiovascular activity during stress in oppositional-defiant disorder boys and normal controls. Biol Psychiatry 43 (1998) 531-539
51. Van Loon G.R., Shum A., and De Souza E.B. Triphasic changes in plasma ACTH concentration and brain serotonin synthesis rate following adrenalectomy in rats. Neuroendocrinology 34 (1982) 90-94
52. van Praag H.M. Anxiety/Aggression-driven depression. Prog Neuro-Psychopharmacol Biol Psychiatry 25 (2001) 893-924
53. Vanyukov M.M., Moss H.B., Plail J.A., Blackson T., Mezzich A.C., and Tarter R.E. Antisocial symptoms in preadolescent boys and in their parents: associations with cortisol. Psychiatry Res 46 (1993) 9-17
54. Virkkunen M. Urinary free cortisol secretion in habitually violent offenders. Acta Psychiatr Scand 72 (1985) 40-44
55. Whitehead P.D. Causality and collateral estoppel: process and content of recent SSRI litigation. J Am Acad Psychiatry Law 31 (2003) 377-382
56. Woodman D., and Hinton J. Catecholamine balance during stress anticipation: an abnormality in maximum security hospital patients. J Psychosom Res 22 (1978) 477-483
57. Woodworth M., and Porter S. In cold blood: characteristics of criminal homicides as a function of psychopathy. J Abnorm Psychology 111 (2002) 436-445