Reactions of activated lupane oxo-compounds with diazomethane: An approach to new derivatives of cytotoxic triterpenes

Synthesis

Volumn , Issue 23, 2006, Pages 3979-3986

  Urban, Milan ^a,c   Klinot, Jiri ^a   Tislerova, Iva ^a   Biedermann, David ^a   Hajduch, Marian ^b   Cisarova, Ivana ^a   Sarek, Jan ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b PALACKÝ UNIVERSITY   (Czech Republic)

^c INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

Author keywords

Addition reactions; Antitumor agents; Diazo compounds; Ketones; Terpenoids

Indexed keywords

ADDITION REACTIONS; ALDEHYDES; CHEMICAL ACTIVATION; DERIVATIVES; KETONES; OLEFINS;

ANTITUMOR AGENTS; DIAZO COMPOUNDS; TERPENOIDS;

PARAFFINS;

(PIVALOYLOXY)METHYL 3BETA ACETOXY 21,22 DIOXOLUP 18 EN 28 OATE; 1,2 DICARBONYL DERIVATIVE; 18,19 SECO TRIKETONE DERIVAIVE; 18,19,21 TRIOXO 18,18 SECOLUPANE 3BETA 28 DIYL DIACETATE; 3 METHOXY 2 CYCLOHEXENONE; 30 OXOLUP 20(29) ENE 28 OIC ACID; ACETOXYMETHYL 3BETA ACETOXY 21,22 DIOXOLUP 18 EN 28 OATE; ALDEHYDE; CYCLOPROPANE; DIAZOMETHANE; DIHYDROPYRAZOLE; DIHYDROPYRAZOLE DERIVATIVE; ENOLETHER; ENOLETHER ACETIC ACID; EPOXY ACM ESTER; EPOXY POM ESTER; EPOXYDIKETONE; EPOXYMETHYL ESTER; ETHYLENE OXIDE; HOMOKETONE; KETONE DERIVATIVE; METHYL 30 OXOLUP 20(29) EN 28 OATE; METHYL 3BETA ACETOXY 18,19,21 TRIOXO 18,19 SECOLUPAN 28 OATE; METHYL 3BETA ACETOXY 21,22 DIOXOLUP 18 EN 28 OATE; PIVALOYLOXYMETHYL 3BETA ACETOXY 18,19,21 TRIOXO 18,19 SECOLUPAN 28 OATE; PYRAZOLE DERIVATIVE; TRITERPENE DERIVATIVE;

ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LYMPHATIC LEUKEMIA; STRUCTURE ACTIVITY RELATION;

EID: 33845611071     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-950327     Document Type: Article

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