Mibefradil-sensitive component involved in the plateau potential in submucosal interstitial cells of the murine proximal colon

Biochemical and Biophysical Research Communications

Volumn 353, Issue 1, 2007, Pages 170-176

  Hotta, Aya ^a   Okada, Noriko ^a   Suzuki, Hikaru ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

Interstitial cells of Cajal; Mibefradil; Plateau potential; Proximal colon; T type Ca2+ channel

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL T TYPE; MIBEFRADIL; NICKEL; NIFEDIPINE; POTASSIUM; VOLTAGE DEPENDENT ANION CHANNEL;

ACTION POTENTIAL; ANIMAL TISSUE; ARTICLE; ASCENDING COLON; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG SENSITIVITY; INHIBITION KINETICS; INTERSTITIAL CELL OF CAJAL; MALE; MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUBMUCOSA;

ACTION POTENTIALS; ANIMALS; BIOLOGICAL CLOCKS; CALCIUM CHANNEL BLOCKERS; CELLS, CULTURED; COLON; DOSE-RESPONSE RELATIONSHIP, DRUG; INTESTINAL MUCOSA; MALE; MEMBRANE POTENTIALS; MIBEFRADIL; MICE; MICE, INBRED BALB C; SUBMUCOUS PLEXUS;

MURINAE;

EID: 33845605491     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.12.003     Document Type: Article

References (28)

1. Takaki M. Gut pacemaker cells: the interstitial cells of Cajal. J. Smooth Muscle Res. 39 (2003) 55-65
2. Sanders K.M., Koh S.D., and Ward S.M. Interstitial cells of cajal as pacemakers in the gastrointestinal tract. Annu. Rev. Physiol. 68 (2006) 307-343
3. Huizinga J.D., Thuneberg L., Kluppel M., Malysz J., Mikkelsen H.B., and Bernstein A. W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature (Lond.) 373 (1995) 347-349
4. Komuro T. Comparative morphology of interstitial cells of Cajal: ultrastructural characterization. Microsc. Res. Tech. 47 (1999) 267-285
5. Barajas-López C., and Huizinga J.D. Different mechanisms of contraction generation in circular muscle of canine colon. Am. J. Physiol. 256 (1989) G570-G580
6. Plujà L., Albertí E., Fernández E., Mikkelsen H.B., Thuneberg L., and Jiménez M. Evidence supporting presence of two pacemakers in rat colon. Am. J. Physiol. 281 (2000) G255-G266
7. Yoneda S., Takano H., Takaki M., and Suzuki H. Properties of spontaneously active cells distributed in the submucosal layer of mouse proximal colon. J. Physiol. (Lond.) 542 (2002) 887-897
8. + channel (Kv1.1) in interstitial cells of Cajal. J. Physiol. 533 (2001) 315-327
9. + currents regulate pacemaker activity in ICC. Am. J. Physiol. 285 (2003) G1249-G1258
10. - current and physiological roles of the intestinal c-kit-positive cells. Pflügers Arch. Eur. J. Physiol. 431 (1995) 169-177
11. Huizinga J.D., Zhu Y., Ye J., and Molleman A. High-conductance chloride channels generate pacemaker currents in interstitial cells of Cajal. Gastroenterology 123 (2002) 1627-1636
12. Torihashi S., Fujimoto T., Trost C., and Nakayama S. Calcium oscillation linked to pacemaking of interstitial cells of Cajal: requirement of calcium influx and localization of TRP4 in caveolae. J. Biol. Chem. 277 (2002) 19191-19197
13. Kim Y.C., Koh S.D., and Sanders K.M. Voltage-dependent inward currents of interstitial cells of Cajal from murine colon and small intestine. J. Physiol. (Lond.) 541 (2002) 797-810
14. Suzuki H., Takano H., Yamamoto Y., Komuro T., Saito M., Kato K., and Mikoshiba K. Properties of gastric smooth muscles obtained from mice which lack inositol trisphosphate receptor. J. Physiol. (Lond.) 525 (2000) 563-573
15. Hirst G.D., and Edwards F.R. Generation of slow waves in the antral region of guinea-pig stomach-a stochastic process. J. Physiol. (Lond.) 535 (2001) 165-180
16. 2+ uptake in canine colonic muscles. J. Physiol. (Lond.) 549 (2003) 207-218
17. 2+ activity in ICC and HEK293 cells. J. Cell Sci. 117 (2004) 2813-2825
18. - channels. J. Physiol. (Lond.) 540 (2002) 907-919
19. Hotta A., Kito Y., and Suzuki H. The effects of flufenamic acid on spontaneous activity of smooth muscle tissue isolated from the guinea-pig stomach antrum. J. Smooth Muscle Res. 41 (2005) 207-220
20. Hotta A., Kim Y.C., Nakamura E., Kito Y., Yamamoto Y., and Suzuki H. Effects of inhibitors of nonselective cation channels on the acetylcholine-induced depolarization of circular smooth muscle from the guinea-pig stomach antrum. J. Smooth Muscle Res. 41 (2005) 313-327
21. 2+ channels by Ro 40-5967. Circ. Res. 75 (1994) 144-148
22. Martin R.L., Lee J.H., Cribbs L.L., Perez-Reyes E., and Hanck D.A. Mibefradil block of cloned T-type calcium channels. J. Pharmacol. Exp. Ther. 295 (2000) 302-308
23. Lee J.H., Gomora J.C., Cribbs L.L., and Perez-Reyes E. Nickel block of three cloned T-type calcium channels: low concentrations selectively block α1H. Biophys. J. 77 (1999) 3034-3042
24. Ward S.M., Ördög T., Koh S.D., Abu Baker S., Jun J.Y., Amberg G., Monaghan K., and Sanders K.M. Pacemaking in interstitial cells of Cajal depends upon calcium handling by endoplasmic reticulum and mitochondria. J. Physiol. (Lond.) 525 (2000) 355-361
25. 2+ signals in interstitial cells of Cajal and longitudinal smooth muscle cells during rhythmic activity in mouse ileum. J. Physiol. (Lond.) 538 (2002) 823-835
26. Perez-Reyes E. Molecular physiology of low-voltage-activated T-type calcium channels. Physiol. Rev. 83 (2003) 117-161
27. Kobayashi S., Chowdhury J.U., Tokuno H., Nahar S., and Iino S. A smooth muscle nodule producing 10-12 cycles/min regular contractions at the mesenteric border of the pacemaker area in the guinea-pig colon. Arch. Histol. Cytol. 59 (1996) 159-168
28. Yoneda S., Fukui H., and Takaki M. Pacemaker activity from submucosal interstitial cells of Cajal drives high-frequency and low-amplitude circular muscle contractions in the mouse proximal colon. Neurogastroenterol. Motil. 16 (2004) 621-627