Stoichiometric analysis and experimental investigation of glycerol-glucose co-fermentation in Klebsiella pneumoniae under microaerobic conditions

Biochemical Engineering Journal

Volumn 33, Issue 1, 2007, Pages 42-52

  Xiu, Zhi Long ^a   Chen, Xi ^a   Sun, Ya Qin ^a   Zhang, Dai Jia ^a  

^a DALIAN UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

1,3 Propanediol; Glucose; Glycerol; Klebsiella pneumoniae; Stoichiometric analysis

Indexed keywords

ADENOSINETRIPHOSPHATE; CARBOXYLIC ACIDS; FERMENTATION; GLUCOSE; MICROORGANISMS; OXIDATION; STOICHIOMETRY;

1,3-PROPANEDIOL; KLEBSIELLA PNEUMONIAE; STOICHIOMETRIC ANALYSIS;

GLYCEROL;

1,3 PROPANEDIOL; ACETYL COENZYME A ACETYLTRANSFERASE; CARBON; GLUCOSE; GLYCEROL; OXYGEN; TRICARBOXYLIC ACID;

AEROBIC FERMENTATION; ARTICLE; BACTERIUM CULTURE; BIOMASS FERMENTATION; CITRIC ACID CYCLE; CITROBACTER; CLOSTRIDIA; ENTEROBACTER; ENZYME SUBSTRATE; GENETIC ENGINEERING; KLEBSIELLA PNEUMONIAE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PURIFICATION; STOICHIOMETRY;

KLEBSIELLA PNEUMONIAE;

EID: 33845584897     PISSN: 1369703X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bej.2006.09.027     Document Type: Article

References (32)

1. Alper J. Engineering metabolism for commercial gains. Science 283 (1999) 1625-1626
2. Biebl H., Menzel K., Zeng A.P., and Deckwer W.D. Microbial production of 1,3-propanediol. Appl. Microbiol. Biotechnol. 52 (1999) 289-297
3. Tong I.T., and Cameron D. Enhancement of 1,3-propanediol production by cofermentation in Escherichia coli expressing Klebsiella pneumoniae dha regulon genes. Appl. Biochem. Biotechnol. 34/35 (1992) 149-159
4. Nakamura C.E., and Whited G.M. Metabolic engineering for the microbial production of 1,3-propanediol. Curr. Opin. Technol. 14 (2003) 454-459
5. Menzel K., Zeng A.P., and Deckwer .W.D. High concentration and productivity of 1,3-propanediol from continuous fermentation of glycerol by Klebsiella pneumoniae. Enzyme Microb. Technol. 20 (1997) 82-86
6. Papanikolaou S., Ruiz-Sanchez P., Pariset B., Blanchard F., and Fick M. High production of 1,3-propanediol from industrial glycerol by a newly isolated Clostridium butyricum strain. J. Biotechnol. 77 (2000) 191-208
7. Papanikolaou S., Fick M., and Aggelis G. The effect of raw glycerol concentration on the production of 1,3-propanediol by Clostridium butyricum. J. Chem. Technol. Biotechnol. 79 (2004) 1189-1196
8. Barbirato F., Astruc S., Soucaille P., Camarasa C., Salmon J.M., and Bories A. Anaerobic pathways of glycerol dissimilation by Enterobacter agglomerans CNCM 1210: limitations and regulations. Microbiology 143 (1997) 2423-2432
9. Barbirato F., Himmi H.E., Conte T., and Bories A. 1,3-Propanediol production by fermentation: an interesting way to valorize glycerin from the ester and ethanol industries. Ind. Crops Prod. 7 (1998) 281-289
10. Boenigk R., Bowien S., and Gottschalk G. Fermentation of glycerol in continuous cultures of Citrobacter freundii. Appl. Microbiol. Biotechnol. 38 (1993) 453-457
11. Zeng A.P., Biebl H., Schlieker H., and Deckwer W.D. Pathway analysis of glycerol fermentation by Klebsiella pneumoniae: regulation of reducing equivalent balance and product formation. Enzyme Microb. Technol. 15 (1993) 770-779
12. Chen X., Xiu Z.L., Wang J.F., Zhang D.J., and Xu P. Stoichiometric analysis and experimental investigation of glycerol bioconversion to 1,3-propanediol by Klebsiella pneumoniae under microaerobic conditions. Enzyme Microb. Technol. 33 (2003) 386-394
13. Menzel K., Ahrens K., Zeng A.P., and Deckwer W.D. Kinetic, dynamic, and pathway studies of glycerol metabolism by Klebsiella pneumoniae in anaerobic continuous culture. IV. Enzymes and fluxes of pyruvate metabolism. Biotechnol. Bioeng. 60 (1998) 617-626
14. Bozell J. Oleochemicals as a Feedstock for the Biorefinery: High Value Products from Fats and Oils (2004), Biorenewables Initiative Publications, Iowa State University, IA
15. K. Tran-Dinh, F.F. Hill, Verfahren zur Herstellung von Propandiol-(1,3), German Patent No. DE 37,34,764 A1 (1987).
16. Abbad-Andaloussi S., Amine J., Gerard P., and Petitdemange H. Effect of glucose on glycerol metabolism by Clostridium butyricum DSM 5431. J. Appl. Microbiol. 84 (1998) 515-522
17. Zhang J., Zhao H.Y., Liu H.J., Xiang B.T., and Liu D.H. Fermentation production of 1,3-propanediol by using glucose as cosubstrate. Mod. Chem. Ind. (Xian Dai Hua Gong Chin.) 22 (2002) 32-35
18. Yang D., Li C., Du C.-Y., Zhang Y.-P., and Cao Z.-A. Production of 1,3-propanediol by Klebsiella pneumoniae in two stage two substrate fermentation. Chin. J. Process Eng. (Guo Cheng Gong Cheng Xue Bao Chin.) 3 (2003) 269-273
19. Biebl H., and Marten S. Fermentation of glycerol to 1,3-propanediol: use of cosubstrates. Appl. Microbiol. Biotechnol. 44 (1995) 15-19
20. Malaoui H., and Marczak R. Influence of glucose on glycerol metabolism by wild-type and mutant strains of Clostridium butyricum E5 grown in chemostat culture. Appl. Microbiol. Biotechnol. 55 (2001) 226-233
21. Wang J.F., Xiu Z.L., Liu H.J., and Fan S.D. Study on microaerobic conversion of glycerin to 1,3-propanediol by Klebsiella pneumoniae. Mod. Chem. Ind. (Xian Dai Hua Gong Chin.) 21 (2001) 28-31
22. Huang H., Gong C.S., and Tsao G.T. Production of 1,3-propanediol by Klebsiella pneumonia. Appl. Biochem. Biotechnol. 98-100 (2002) 687-698
23. Chen X., Zhang D.J., Qi W.T., Gao S.J., Xiu Z.L., and Xu P. Microbial fed-batch production of 1,3-propanediol by Klebsiella pneumoniae under micro-aerobic conditions. Appl. Microbiol. Biotechnol. 63 (2003) 143-146
24. Zeng A.P., Biebl H., and Deckwer W.D. Microbial conversion of glycerol to 1,3-propanediol: recent progress. In: Saha B.C., and Woodward J. (Eds). Fuels and Chemicals from Biomass (1997), American Chemical Society 265-279
25. Homann T., Tag C., Biebl H., Deckwer W.D., and Schink B. Fermentation of glycerol to 1,3-propanediol by Klebsiella and Citrobacter strains. Appl. Microbiol. Biotechnol. 33 (1990) 121-126
26. Zhou J., Chen Z.Q., and Hu J. Comparison study on the determination of glucose with F Fehling method and glucose analyser. Ind. Microbiol. (Gong Ye Wei Sheng Wu Chin.) 29 (1999) 34-36
27. Cheng K.K., Ling H.Z., Zhang L.L., Sun Y., and Liu D.H. Effect of glucose as cosubstrate on 1,3-propanediol fermentation by Klebsiella pneumoniae. Chin. J. Process Eng. 4 (2004) 561-566
28. G. Gottschalk, B. Averhoff, Process for the microbiological preparation of 1,3-propanediol from glycerol, European Patent No. 0373230 A1 (1988).
29. Menzel K., Zeng A.P., and Deckwer W.D. Enzymatic evidence for an involvement of pyruvate dehydrogenase in the anaerobic glycerol metabolism of Klebsiella pneumoniae. J. Biotechnol. 56 (1997) 135-142
30. Papanikolaou S., Muniglia L., Chevalot I., Aggelis G., and Marc I. Yarrowia lipolytica as a potential producer of citric acid from raw glycerol. J. Appl. Microbiol. 92 (2002) 737-744
31. Alvarez M.F., Medina R., Pasteris S., Strasser de Saad A.M., and Sesma F. Glycerol metabolism of Lactobacillus rhamnosus ATCC 7469: cloning and expression og two glycerol kinase genes. J. Mol. Microbiol. Biotechnol. 7 (2004) 170-181
32. Veiga M.C., and Foster M.A. Sugar-glycerol cofermentations in lactobacilli: the fate of lactate. J. Bacteriol. 3 (1992) 1013-1019