Dihydroxydocosahexaenoic acids of the neuroprotectin D family: Synthesis, structure, and inhibition of human 5-lipoxygenase

Journal of Lipid Research

Volumn 47, Issue 11, 2006, Pages 2462-2474

  Butovich, Igor A ^a   Lukyanova, Svetlana M ^a   Bachmann, Carl ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

10,17 dihydroxydocosahexaenoic acid; 7,17 dihydroxydocosahexaenoic acid; Docosahexaenoic acid; Double lipoxygenation; Neuroprotectins D1 and D5; Protectins D1 and D5

Indexed keywords

10,17 DIHYDROXYDOCOSAHEXAENOIC ACID; 17 DIHYDROPEROXYDOCOSAHEXAENOIC ACID; 17 DIHYDROXYDOCOSAHEXAENOIC ACID; 7,17 DIHYDROPEROXYDOCOSAHEXAENOIC ACID; 7,17 DIHYDROXYDOCOSAHEXAENOIC ACID; ANTIINFLAMMATORY AGENT; ARACHIDONATE 5 LIPOXYGENASE; DIHYDROXYDOCOSAHEXAENOIC ACID; DOCOSAHEXAENOIC ACID; NEUROPROTECTIN D;

ARTICLE; CATALYSIS; CHIRALITY; DRUG INHIBITION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; FATTY ACID OXIDATION; GAS CHROMATOGRAPHY; GEOMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXYGENATION; POTATO; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; ULTRAVIOLET SPECTROSCOPY;

ARACHIDONATE 5-LIPOXYGENASE; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOCOSAHEXAENOIC ACIDS; ENZYME INHIBITORS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; INHIBITORY CONCENTRATION 50; LIPOXYGENASE; MAGNETIC RESONANCE SPECTROSCOPY; OXYGEN; SOYBEANS;

EID: 33845571904     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M600280-JLR200     Document Type: Article

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