Synthesis and biological activity of seleno sunflower trypsin inhibitor analog

Chemical Biology and Drug Design

Volumn 68, Issue 6, 2006, Pages 341-344

  Guo, Xin ^a   Shi, Jiahao ^b   Tang, Zhenyu ^b   Cui, Dafu ^b   Zhang, Youshang ^a,b  

^a TONGJI UNIVERSITY   (China)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

Isosteric replacement; Peptide synthesis; Seleno sunflower trypsin inhibitor

Indexed keywords

CYCLOPEPTIDE; PROTEIN SFTI 1; SELENIUM DERIVATIVE; SUNFLOWER TRYPSIN INHIBITOR; SUNFLOWER TRYPSIN INHIBITOR DERIVATIVE; TRYPSIN INHIBITOR;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DISULFIDE BOND; PEPTIDE ANALYSIS; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; MOLECULAR SEQUENCE DATA; PEPTIDES; PEPTIDES, CYCLIC; SELENOPROTEINS; TRYPSIN; TRYPSIN INHIBITORS;

HELIANTHUS;

EID: 33845565683     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2006.00457.x     Document Type: Article

References (6)

1. Atkins J.F., Gsteland R.F. (2000) The twenty-first amino acid. Nature;407:463-465.
2. Stadtman T.C. (1996) Selenocysteine. Annu Rev Biochem;65:83-100.
3. Luckett S., Garcia R.S., Barker J.J., Konarev A.V., Shewry P.R., Clarke A.R., Brady R.L. (1999) High-resolution structure of a potent, cyclic proteinase inhibitor from sunflower seeds. J Mol Biol;290:525-533.
4. 1H NMR of the novel cyclic trypsin inhibitor SFTI-1-1 from sunflower seeds and an acyclic permutant. J Mol Biol;311:579-591.
5. Nicklin M.J.H., Barrett A.J. (1984) Inhibition of cysteine proteinases and dipeptidyl peptidase I by egg-white cystatin. Biochem J;223:245-253.
6. Koide T., Itoh H., Otaka A., Yasui H., Kuroda M., Esaki N., Soda K., Fujii N. (1993) Synthetic study on selenocystine containing peptides. Chem Pharm Bull;41:502-506.