Disruption of the ifkA and ifkB genes results in altered cell adhesion, morphological defects and a propensity to form pre-stalk O cells during development of Dictyostelium

Differentiation

Volumn 74, Issue 9-10, 2006, Pages 583-595

  Rai, Meena ^a   Xiong, Yanhua ^a   Singleton, Charles K ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

Adhesion; Dictyostelium; eIF2 kinase; GCN2; Patterning; Pre stalk cells; STAT

Indexed keywords

STAT PROTEIN; STATC PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CELL ADHESION; CELL MATURATION; CELL STRUCTURE; CELL TYPE; CONTROLLED STUDY; DICTYOSTELIUM; GENE; GENE DISRUPTION; GENETIC DISORDER; IFKA GENE; IFKB GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATTERN RECOGNITION; PLANT CELL; PLANT GENETICS; PLANT GROWTH; PLANT STEM; PRIORITY JOURNAL;

DICTYOSTELIUM;

EID: 33845539293     PISSN: 03014681     EISSN: 14320436     Source Type: Journal    
DOI: 10.1111/j.1432-0436.2006.00085.x     Document Type: Article

References (70)

1. Abe, F. and Maeda, Y. (1994) Precise expression of the cAMP receptor gene, car1, during transition from growth to differentiation in Dictyostelium discoideum. FEBS Lett. 342:239-241.
2. Abe, T., Early, A., Siegert, F., Weijer, C. and Williams, J. (1994) Patterns of cell movement within the Dictyostelium slug revealed by cell type-specific, surface labeling of living cells. Cell 77:687-699.
3. Alton, T.H. (1977) Regulation of protein synthesis during development of the cellular slime mold Dictyostelium discoideum. Massachusetts Institute of Technology (MIT), Cambridge, MA.
4. Anjard, C., Zeng, C., Loomis, W.F. and Nellen, W. (1998) Signal transduction pathways leading to spore differentiation in Dictyostelium discoideum. Dev Biol 193:146-155.
5. Araki, T., Tsujioka, M., Abe, T., Fukuzawa, M., Meima, M., Schaap, P., Morio, T., Urushihara, H., Katoh, M., Maeda, M., Tanaka, Y., Takeuchi, I. and Williams, J.G. (2003) A STAT-regulated, stress-induced signaling pathway in Dictyostelium. J Cell Sci 116:2907-2915.
6. Bichler, G. and Weijer, C.J. (1994) A Dictyostelium anterior-like cell mutant reveals sequential steps in the prespore prestalk differentiation pathway. Development 120:2857-2868.
7. Blaschke, A., Weijer, C. and MacWilliams, H. (1986) Dictyostelium discoideum: cell-type proportioning, cell-differentiation preference, cell fate, and the behavior of anterior-like cells in Hs1/Hs2 and G1/G mixtures. Differentiation 32:1-9.
8. Bonner, J.T. (1957) A theory of the control of differentiation in the cellular slime molds. Quart Rev Biol 32:232-246.
9. Braga, V. and Harwood, A.J. (2001) Super glue. Nat Cell Biol 3:E168-E170.
10. Casademunt, E., Varney, T.R., Dolman, J., Petty, C. and Blumberg, D.D. (2002) A gene encoding a novel anti-adhesive protein is expressed in growing cells and restricted to anterior-like cells during development of Dictyostelium. Differentiation 70:23-35.
11. Chia, C.P., Gomathinayagam, S., Schmaltz, R.J. and Smoyer, L.k. (2005) Glycoprotein gp130 of Dictyostelium discoideum influences macropinocytosis and adhesion. Mol Biol Cell 16:2681-2693.
12. Clow, P.A., Chen, T.L.L., Chisholm, R.L. and McNally, J.G. (2000) Three-dimensional in vivo analysis of Dictyostelium mounds reveals directional sorting of prestalk cells and defines a role for the myosin II regulatory light chain in prestalk cell sorting and tip protrusion. Development 127:2715-2728.
13. Coates, J.C. and Harwood, A.J. (2001) Cell-cell adhesion and signal transduction during Dictyostelium development. J Cell Sci 114:4349-4358.
14. Dever, T., Feng, T., Wek, R., Cigan, A., Donahue, T. and Hinnebusch, A. (1992) Phosphorylation of initiation factor 2α by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast. Cell 1992:585-596.
15. Devine, K.M. and Loomis, W.F. (1985) Molecular characterization of anterior-like cells in Dictyostelium discoideum. Dev Biol 107:364-372.
16. Devreotes, P.N. (1994) G protein-linked signaling pathways control the developmental program of Dictyostelium. Neuron 12:235-241.
17. Dimilla, P.A., Stone, J.A., Quinn, J.A., Albelda, S.M. and Lauffenburger, D.A. (1993) Maximal migration of human smooth muscle cells on fibronectin and type IV collagen occurs at an intermediate attachment strength. J Cell Biol 122:729-737.
18. Dingermann, T., Reindl, N., Werner, H., Hildebrandt, M., Nellen, W., Harwood, A., Williams, J. and Nerke, K. (1989) Optimization and in situ detection of Escherichia coli beta-galactosidase gene expression in Dictyostelium discoideum. Gene 85:353-362.
19. Doolittle, K.W., Reddy, I. and McNally, J.G. (1995) 3D analysis of cell movement during normal and myosin-II-null cell morphogenesis in Dictyostelium. Dev Biol 167:118-129.
20. Dormann, D., Siegert, F. and Weijer, C.J. (1996) Analysis of cell movement during the culmination phase of Dictyostelium development. Development 122:761-769.
21. Dormann, D., Vasiev, B. and Weijer, C.J. (2000) The control of chemotactic cell movement during Dictyostelium morphogenesis. Phil Trans Roy Soc Lond B 355:983-991.
22. Dynes, J.L., Clark, A.M., Shaulsky, G., Kuspa, A., Loomis, W.F. and Firtel, R.A. (1994) LagC is required for cell-cell interactions that are essential for cell-type differentiation in Dictyostelium. Genes Dev 8:948-958.
23. Early, A., Abe, T. and Williams, J. (1995) Evidence for positional differentiation of prestalk cells and for a morphogenetic gradient in Dictyostelium. Cell 83:91-99.
24. Early, A.E., Gaskell, M.J., Traynor, D. and Williams, J.G. (1993) Two distinct populations of prestalk cells within the tip of the migratory Dictyostelium slug with differing fates at culmination. Development 118:353-362.
25. Fang, R., Xiong, Y. and Singleton, C.K. (2003) IfkA, a presumptive eIF2alpha kinase of Dictyostelium, is required for proper timing of aggregation and regulation of mound size. BMC Dev Biol 3:3.
26. Fukuzawa, M., Abe, T. and Williams, J.G. (2003) The Dictyostelium prestalk cell inducer DIF regulates nuclear accumulation of a STAT protein by controlling its rate of export from the nucleus. Development 130:797-804.
27. Fukuzawa, M., Araki, T., Adrian, I. and Williams, J.G. (2001) Tyrosine phosphorylation-independent nuclear translocation of a Dictyostelium STAT in response to DIF signaling. Mol Cell 7:779-788.
28. Gao, E.N., Shier, P. and Siu, C.H. (1992) Purification and partial characterization of a cell adhesion molecule (gp150) involved in postaggregation stage cell-cell binding in Dictyostelium discoideum. J Biol Chem 267:9409-9415.
29. Harding, H., Novoa, I., Zhang, Y., Zeng, H., Wek, R., Schapira, A.M. and Ron, D. (2000) Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell 6:1099-1108.
30. Hinnenbusch, A. (1996) Translational control of GCN4: Genespecific regulation by phosphorylation of eIF-2. In Translational Control, Hershey, J., Mathews, M. and Sonenberg, N. eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 199-244.
31. Jermyn, K., Traynor, D. and Williams, J. (1996) The initiation of basal disc formation in Dictyostelium discoideum is an early event in culmination. Development 122:753-760.
32. Jermyn, K.A., Duffy, K.T. and Williams, J.G. (1989) A new anatomy of the prestalk zone in Dictyostelium. Nature 340:144-146.
33. Kamboj, R.K., Lam, T.Y. and Siu, C.-H. (1990) Regulation of slug size by the cell adhesion molecule gp80 in Dictyostelium discoideum. Cell Regulation 1:715-729.
34. Kay, R.R. and Thompson, C.R.L. (2001) Cross-induction of cell types in Dictyostelium: evidence that DIF-1 is made by prespore cells. Development 128:4959-4966.
35. Kimmel, A. and Firtel, R. (2004) Breaking symmetries: regulation of Dictyostelium development through chemoattractant and morphogen signal-response. Curr Opin Genet Dev 14:540-549.
36. Kirsten, J., Xiong, Y., Dunbar, A., Rai, M. and Singleton, C. (2005) Ammonium transporter C of Dictyostelium discoideum is required for correct prestalk gene expression and for regulating the choice between slug migration and culmination. Dev Biol 287:146-156.
37. Knecht, D.A., Fuller, D.L. and Loomis, W.F. (1987) Surface glycoprotein, gp24, involved in early adhesion of Dictyostelium discoideum. Dev Biol 121:277-283.
38. Konijn, T.M., van de Meene, J.G.C., Bonner, J.T. and Barkley, D.S. (1967) The acrasin activity of adenosine-3′,5′-cyclic phosphate. Proc Natl Acad Sci USA 58:1152-1154.
39. Margolskee, J.P., Froshauer, S., Skrinska, R. and Lodish, H.F. (1980) The effects of cell density and starvation on early developmental events in Dictyostelium discoideum. Dev Biol 74:409-421.
40. Margolskee, J.P. and Lodish, H.F. (1980) The regulation of the synthesis of actin and two other proteins induced early in Dictyostelium discoideum development. Dev Biol 74:50-64.
41. Marin, F.T. (1976) Regulation of development in Dictyostelium discoideum: I. Initiation of the growth to developmental transition by amino acid starvation. Dev Biol 48:110-117.
42. Marin, F.T. (1977) Regulation of development in Dictyostelium discoideum: II. Regulation of early cell differentiation by amino acid starvation and intercellular interaction. Dev Biol 60:389-395.
43. Milocco, L.H., Haslam, J.A., Rosen, J. and Seidel, H.M. (1999) Design of conditionally active STATs: insights into STAT activation and gene regulatory function. Mol Cell Biol 19:2913-2920.
44. Mohanty, S., Jermyn, K.A., Early, A., Kawata, T., Aubry, L., Ceccarelli, A., Schaap, P., Williams, J.G. and Firtel, R.A. (1999) Evidence that the Dictyostelium Dd-STATa protein is a repressor that regulates commitment to stalk cell differentiation and is also required for efficient chemotaxis. Development 126:3391-3405.
45. Morris, H.R., Taylor, G.W., Masento, M.S., Jermyn, K.A. and Kay, R.R. (1987) Chemical structure of the morphogen differentiation inducing factor from Dictyostelium discoideum. Nature 328:811-814.
46. Nellen, W., Silan, C. and Firtel, R. (1984) DNA-mediated transformation in Dictyostelium discoidium. Regulated expression of an actin gene fusion. Mol Cell Biol 4:2890-2898.
47. Pekovich, S.R., Martin, P.R. and Singleton, C.K. (1998) Thiamine deficiency decreases steady-state mRNA levels for transketolase and pyruvate dehydrogenase but not for a-ketoglutarate dehydrogenase in three human cell types. J Nutr 128:683-687.
48. Richardson, D.L., Loomis, W.F. and Kimmel, A.R. (1994) Progression of an inductive signal activates sporulation in Dictyostelium discoideum. Development 120:2891-2900.
49. Rietdorf, J., Siegert, F. and Weijer, C.J. (1996) Analysis of optical density wave propagation and cell movement during mound formation in Dictyostelium discoideum. Dev Biol 177:427-438.
50. 2+-dependent cell adhesion molecule DdCAD-1 during development of Dictyostelium discoideum. Dev Biol 177:504-516.
51. Shaulsky, G., Kuspa, A. and Loomis, W.F. (1995) A multidrug resistance transporter serine protease gene is required for prestalk specialization in Dictyostelium. Genes Dev 9:1111-1122.
52. Shaulsky, G. and Loomis, W.F. (1996) Initial cell type divergence in Dictyostelium is independent of DIF-1. Dev Biol 174:214-220.
53. Shimada, N., Maruo, T.M.M., Urushihara, H. and Kawata, T. (2005) Evidence that the Dictyostelium STAT protein Dd-STATa plays a role in the differentiation of inner basal disc cells and identification of a promoter element essential for expression in these cells. Differentiation 73:50-60.
54. Singleton, C.K. (1989) Nucleotide sequence of VI, a ribosomal protein gene from Dictyostelium discoideum. Nucleic Acids Res 17:7989.
55. Singleton, C.K., Delude, R.L. and McPherson, C.E. (1987) Characterization of genes which are deactivated upon the onset of development in Dictyostelium discoideum. Dev Biol 119:433-441.
56. Singleton, C.K., Zinda, M.J., Mykytka, B. and Yang, P. (1998) The histidine kinase DhkC regulates the choice between migrating slugs and terminal differentiation in Dictyostelium discoideum. Dev Biol 203:345-357.
57. Siu, C.-H. (2004) Regulation of cell-cell adhesion during Dictyostelium development. Semin Cell Dev Biol 15:633-641.
58. Siu, C.-H., Cho, A. and Choi, H.C. (1987) The contact site A glycoprotein mediates cell-cell adhesion by homophilic binding in Dictyostelium discoideum. J Cell Biol 105:2523-2533.
59. Sternfeld, J. (1992) A study of pstB cells during Dictyostelium migration and culmination reveals a unidirectional cell type conversion process. W R Arch Dev Biol 201:354-363.
60. Sternfeld, J. (1998a) The anterior-like cells in Dictyostelium are required for the elevation of the spores during culmination. Dev Genes Evol 208:487-494.
61. Sternfeld, J. (1998b) The anterior-like cells in Dictyostelium are required for the elevation of the sporduring culmination. Dev Genes Evol 208:487-494.
62. Sternfeld, J. and David, C.N. (1982) Fate and regulation of anterior-like cells in Dictyostelium slugs. Dev Biol 93:111-118.
63. Sutoh, K. (1993) A transformation vector for Dictyostelium discoideum with a new selectable marker bsr. Plasmid 30:150-154.
64. Thompson, C.R.L. and Kay, R.R. (2000) The role of DIF-1 signaling in Dictyostelium development. Mol Cell 6:1509-1514.
65. Thompson, C.R.L., Reichelt, S. and Kay, R.R. (2004) A demonstration of pattern formation without positional information in Dictyostelium. Dev Growth Differ 46:363-369.
66. Varney, T.R., Casademunt, E., Ho, H.N., Petty, C., Dolman, J. and Blumberg, D.D. (2002) A novel Dictyostelium gene encoding multiple repeats of adhesion inhibitor-like domains has effects on cell-cell and cell-substrate adhesion. Dev Biol 243:226-248.
67. Williams, J. and Jermyn, K. (1991) Cell sorting and positional differentiation during Dictyostelium morphogenesis. In: Gerhardt, J. ed. Cell-Cell Interactions in Early Development. Wiley, New York.
68. Yu, Y.M. and Saxe, C.L. III (1996) Differential distribution of cAMP receptors cAR2 and cAR3 during Dictyostelium development. Dev Biol 173:353-356.
69. Zhang, Q. (1995) Studies of H7 gene function and regulation of its expression by a bidirectional promoter in Dictyostelium discoideum. Ph.D. thesis, Vanderbilt University, Nashville, TN.
70. Zhukovskaya, N., Fukuzawa, M., Yamada, Y., Araki, T. and Williams, J. (2006) The Dictyostelium bZIP transcription factor DimB regulates prestalk-specific gene expression. Development 133:439-448.