Isolation and structural analysis of an acidic polysaccharide from Astragalus membranaceus (Fisch.) Bunge

Journal of Integrative Plant Biology

Volumn 48, Issue 11, 2006, Pages 1379-1384

  Wang, Shun Chun ^a   Shan, Jun Jie ^a   Wang, Zheng Tao ^a   Hu, Zhi Bi ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Astragalus membranaceus; Hetero polysaccharide; Isolationand purification; Structural analysis

Indexed keywords

CHROMATOGRAPHY; MOLECULAR ANALYSIS; POLYSACCHARIDE;

ASTRAGALUS MEMBRANACEUS;

EID: 33845521919     PISSN: 16729072     EISSN: 17447909     Source Type: Journal    
DOI: 10.1111/j.1744-7909.2006.00325.x     Document Type: Article

References (18)

1. Blakeney AB, Harris PJ, Henry RJ, Stone BA (1983). A simple and rapid preparation of alditol acetates for monosaccharide analysis. Carbohydr Res 113, 291-299.
2. Fang JN, Wagner H (1988). Chemical structure of a glucan from Astragalus mongholicus. Acta Chim Sin 46, 1101-1104 (in Chinese with an English abstract).
3. Fang SD, Cheng Y, Xu XY, Sheng ML, Di SJ, Ye CQ (1982). Studies of the active principles of the Astragalus membranaceus. Chin J Org Chem 2, 26-31 (in Chinese with an English abstract).
4. Gorin PAJ (1981). Carbon-13 nuclear magnetic resonance spectroscopy of polysaccharides. Adv Carbohydr Chem Biochem 38, 13-39.
5. Guo FC, Kwakkel RP, Williams BA, Li WK, Li HS, Luo JY et al. (2004). Effects of mushroom and herb polysaccharides, as alternatives for an antibiotic, on growth performance of broilers. Br Poult Sci 45, 684-694.
6. Huang QS, Lv GB, Li YC, Guo JH, Wang RX (1982). Studies of the polysaccharides of Huangqi (Astragalus membranaceus). Acta Pharm Sin 17, 200-206 (in Chinese with an English abstract).
7. Lee KY, Jeon TJ (2005). Macrophage activation by polysaccharide isolated from Astragalus membranaceus. Int Immunopharmacol 5, 1225-1233.
8. Needs PW, Selvendran RR (1993). Avoiding oxidative degradation during sodium hydroxide/methyl iodide-mediated carbohydrate methylation in dimethyl sulfoxide. Carbohydr Res 245, 1-10.
9. Shimizu N, Tomoda M, Kanari M, Gonda R (1991). An acidic polysaccharide having activity on the reticuloendothelial system from the root of Astragalus mongholicus. Chem Pharm Bull (Tokyo) 39, 2969-2972.
10. Taylor KA, Buchannan-Smith JG (1992). A colorimetric method for the quantitation of uronic acids and a specific assay for galacturonic acid. Anal Biochem 201, 190-196.
11. Taylor RL, Conrad HE (1972). Stoichiometric depolymerization of polyuronides and glycosaminoglycuronans to monosaccharides following reduction of their carbodiimide-activated carboxyl groups. Biochemistry 11, 1383-1388.
12. Tomoda M, Shimizu N, Ohara N, Gonda R, Ishii S, Otsuki H (1992). A reticuloendothelial system-activation glycan from the roots of Astragalus membranaceus. Phytochemistry 31, 63-66.
13. Wang MY, Wu HS (1994). Studies on isolation of Astragalus membranaceus and its immunological activities. Nat Prod Res Dev 6, 23-31 (in Chinese with an English abstract).
14. Wang LX, Han ZW (1992). The effect of Astragalus polysaccharide on endotoxin-induced toxicity in mice. Acta Pharm Sin 27, 5-9 (in Chinese with an English abstract).
15. Wei YA, Fang JN (1989). Determination of purity and molecular weight of polysaccharide by high performance gel permeation chromatography. Acta Pharm Sin 24, 532-536 (in Chinese with an English abstract).
16. Wu Y, Ouyang JP, Wu K, Wang Y, Zhou YF, Wen CY (2005). Hypoglycemic effect of Astragalus polysaccharide and its effect on PTP1B. Acta Pharm Sin 26, 345-352.
17. Zhao KS, Mancini C, Doria G (1990). Enhancement of the immune response in mice by Astragalus membranaceus extracts. Immunopharmacology 20, 225-233.
18. Zou YY, Gu XQ, Cheng Q (1987). Investigation of the polyphaseliposomal bipolysaccharides. J Shenyang Coll Pharm 4, 170-173 (in Chinese with an English abstract).