Diffusion of bioactive molecules through the walls of the medial tissue-engineered hybrid ePTFE grafts for applications in designs of vascular tissue regeneration

Journal of Biomedical Materials Research - Part A

Volumn 79, Issue 4, 2006, Pages 943-953

  Noh, Insup ^a   Choi, Yoon Jeong ^a   Son, Youngsook ^b   Kim, Chun Ho ^b   Hong, Seung Hwa ^c   Hong, Choong Man ^c   Shin, In Soo ^c   Park, Sue Nie ^c   Park, Beom Young ^d  

^a Seoul National University of Science and Technology   (South Korea)

^b Korea Institute of Radiation and Medical Science   (South Korea)

^c Korea Food and Drug Administration   (South Korea)

^d National Institute of Animal Science   (South Korea)

Author keywords

Diffusion; Heparin; Hybrid eptfe scaffold; Tissue engineered vascular grafts; Water

Indexed keywords

BIODEGRADATION; BIOMATERIALS; BLOOD VESSELS; DIFFUSION; PROTEINS; TISSUE CULTURE; WATER;

BIOACTIVE SIGNALS; CAROTID ARTERY; HEPARIN; HYBRID EPTFE SCAFFOLD; TISSUE REGENERATION;

BIOMEDICAL ENGINEERING;

EOSIN; HEMATOXYLIN; HEPARIN; POLITEF; POLYGLACTIN; WATER;

ADVENTITIA; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIODEGRADABILITY; CAROTID ARTERY; CULTURE MEDIUM; DIFFUSION; HYBRID; INTIMA; MORPHOLOGY; NONHUMAN; PERMEABILITY; SCANNING ELECTRON MICROSCOPY; SIGNAL TRANSDUCTION; STAINING; SURFACE PROPERTY; SWINE; TISSUE ENGINEERING; TISSUE REGENERATION; VASCULAR TISSUE;

ABSORBABLE IMPLANTS; ANIMALS; BLOOD VESSEL PROSTHESIS; CAROTID ARTERIES; CELLS, CULTURED; COATED MATERIALS, BIOCOMPATIBLE; DIFFUSION; MYOCYTES, SMOOTH MUSCLE; POLYGLACTIN 910; POLYTETRAFLUOROETHYLENE; PROSTHESIS DESIGN; REGENERATION; SWINE; TISSUE ENGINEERING;

EID: 33845486344     PISSN: 00219304     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.30872     Document Type: Article

References (20)

1. Lovich MA, Edelman ER. Mechanisms of transmural heparin transport in the rat abdominal aorta after local vascular delivery. Circ Res 1995;77:1143-1150.
2. Noh I, Lovich M, Edelman ER. Mechanisms of heparin delivery through expanded poly(tetrafluoroethylene) vascular grafts. J Biomed Mater Res 2000;49:112-119.
3. Wesolowski SA, Fries CC, Karlson KE, Debakey ME, Sawyer PN. Porosity: Primary determinant of the ultimate fate of synthetic vascular grafts. Surgery 1961;50:91-101.
4. Campbell CD, Goldfarb DD, Roe R. A small expanded arterial substitute of expanded microporous polytetrafluoroethylene, patency versus porosity. Ann Surg 1975;182:138-143.
5. Clowes AW, Kirkman TR, Clowes MM. Mechanisms of arterial graft failure. II. Chronic endothelial and smooth muscle cell proliferation in healing polytetrafluoroethylene prostheses. Vasc Surg 1986;3:877-884.
6. Jiang Z, Wu L, Miller BL, Goldman DR, Fernandez CM, Abouhamze ZS, Ozaki CK, Berceli SA. A novel vein graft model: Adaptation to differential flow environments. Am J Physiol Heart Circ Physiol 2004;286:H240-H245.
7. Bacakoglu A, Ozkan MH, Goktay AY, Ekin A. Forearm arterial vein grafting: Problems and alternative solutions. J Int Med Res 2003;31:458-465.
8. Niklason LE, Abbott W, Gao J, Klagges B, Hirschi KK, Ulubayram K, Conroy N, Jones R, Vasanawala A, Sanzgiri S, Langer R. Morphologic and mechanical characteristics of engineered bovine arteries. J Vasc Surg 2001;33:628-638.
9. Noh I. Vascular tissue regeneration of the hybrid ePTFE graft for adult patients. Key Eng Mater 2005;288/289:55-59.
10. Shinoka T, Shum-Tim D, Ma PX, Tanel RE, Isogai N, Langer R, Vacanti JP, Mayer JE Jr. Creation of viable pulmonary artery autografts through tissue engineering. J Thorac Cardiovasc Surg 1998;115:536-546.
11. Langer R, Vacanti JP. Tissue engineering. Science 1993;260:920-926.
12. Choi YJ, Noh I. Media tissue regeneration of the hybrid expanded polytetrafluoroethylene vascular graft via gelatin coating. Curr Appl Phys 2005;5:463-467.
13. Sipe JD. Tissue engineering and reparative medicine. Ann NY Acad Sci 2002;961:1-9.
14. Chrysanthi W, Timothy MW. Perfusion bioreactor for small diameter tissue-engineered arteries. Tissue Eng 2005;10:930-941.
15. Zhang Z, Wang Z, Liu S, Kodama M. Pore size, tissue ingrowth and endothelialization of small-diameter microporous polyurethane vascular prostheses. Biomaterials 2004;25:177-187.
16. Houard X, Monnot C, Dive V, Corvol P, Pagano M. Vascular smooth muscle cells efficiently activate a new proteinase cascade involving plasminogen and fibronectin. J Cell Biochem 2003;88:1188-1201.
17. Ishii C, Imai T, Yagi S, Yamaguchi T, Katayama S. Effect of p53 deficiency on external vascular cuff-induced neointima formation. Circ J 2003;67:149-153.
18. Lovich MA, Philbrook M, Sawyer S, Weselcouch E, Edelman ER. Arterial heparin deposition: Role of diffusion, convection, and extravascular space. Am J Physiol 1998;275:H2236-H2242.
19. Hwang CW, Edelman ER. Arterial ultrastructure influences transport of locally delivered drugs. Circ Res 2002;90:826-832.
20. Baldwin AL, Wilson LM, Gradus-Pizlo I, Wilensky R, March K. Effect of atherosclerosis on transmural convection and arterial ultrastructure: Implications for local intravascular drug delivery. Arterioscler Thromb Vasc Biol 1997;17:3365-3375.