A novel beta-delta globin gene fusion, anti-Lepore Hong Kong, leads to overexpression of delta globin chain and a mild thalassaemia intermedia phenotype when co-inherited with β0-thalassaemia

British Journal of Haematology

Volumn 136, Issue 1, 2007, Pages 158-162

  So, Chi Chiu ^a   Chan, Amy Y Y ^a   Tsang, Stella T Y ^a   Lee, Anselm C W ^b   Au, Wing Yan ^a   Ma, Edmond S K ^a   Chan, Li Chong ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b TUEN MUN HOSPITAL   (Hong Kong)

Author keywords

Anti Lepore; Chinese; Delta chain; Haemoglobin; Thalassaemia

Indexed keywords

DELTA GLOBIN; HEMOGLOBIN A2; MESSENGER RNA;

ARTICLE; BETA THALASSEMIA; CONTROLLED STUDY; DOWN REGULATION; EXON; FEMALE; GENE FUSION; GENE SEQUENCE; GENOTYPE; GLOBIN GENE; HETEROZYGOSITY; HUMAN; HUMAN EXPERIMENT; MALE; MUTATIONAL ANALYSIS; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION SITE;

ADULT; BASE SEQUENCE; BETA-THALASSEMIA; CHILD; DNA PRIMERS; FEMALE; GENE EXPRESSION REGULATION; GENE FUSION; GENOTYPE; GLOBINS; HEMOGLOBIN A2; HEMOGLOBINS, ABNORMAL; HETEROZYGOTE; HONG KONG; HUMANS; MALE; MOLECULAR SEQUENCE DATA; PHENOTYPE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THALASSEMIA; VARIATION (GENETICS);

EID: 33845474518     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2006.06383.x     Document Type: Article

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