Effect of a selective thromboxane A2 synthetase inhibitor on the systemic changes induced by circulating pancreatic phospholipase A2

Journal of Gastroenterology

Volumn 41, Issue 11, 2006, Pages 1094-1098

  Motoyoshi, Makoto ^a,d   Sugiyama, Masanori ^b   Atomi, Yutaka ^b   Kimura, Wataru ^c   Nagawa, Hirokazu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KYORIN UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c YAMAGATA UNIVERSITY   (Japan)

^d TOKYO NATIONAL HOSPITAL   (Japan)

Author keywords

Acute pancreatitis; Arachidonic acid cascade; Phospholipase A2; Plasma lipoprotein; Thromboxane A2

Indexed keywords

BICARBONATE; FIBRINOGEN; LIPOPROTEIN; OZAGREL; PHOSPHOLIPASE A2; PHOSPHOLIPID; THROMBOXANE A2; THROMBOXANE B2; THROMBOXANE SYNTHASE INHIBITOR;

ACUTE PANCREATITIS; ALKALOSIS; ANIMAL EXPERIMENT; ARTICLE; BICARBONATE BLOOD LEVEL; BLOOD GAS ANALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; FIBRINOGEN BLOOD LEVEL; FLUOROMETRY; GUINEA PIG; HEART RATE VARIABILITY; MALE; MEAN ARTERIAL PRESSURE; METABOLIC ACIDOSIS; NONHUMAN; PANCREAS; PATHOGENESIS; PH; PRIORITY JOURNAL; PROTHROMBIN TIME; RADIOIMMUNOASSAY; THROMBOCYTE COUNT; THROMBOCYTOPENIA;

ACUTE DISEASE; ANIMALS; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; GUINEA PIGS; HEART RATE; INJECTIONS, INTRAVENOUS; MALE; METHACRYLATES; PANCREATITIS; PHOSPHOLIPASES A; THROMBOXANE-A SYNTHASE; TREATMENT OUTCOME;

EID: 33845458673     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-006-1892-0     Document Type: Article

References (13)

1. 2 activity in acute pancreatitis: A prognostic marker for early identification of patients at risk Clin Chem Lab Med 40 293-7 10.1515/CCLM.2002.046 1:CAS:528:DC%2BD38Xkt1SksrY%3D 12005220
2. H Nagai H Henrich PH Wunsch W Fischbach J Mossner 1989 Role of pancreatic enzymes and their substrates in autodigestion of the pancreas. In vitro studies with isolated rat pancreatic acini Gastroenterology 96 838-47 1:CAS:528:DyaL1MXhsFaisbg%3D 2914645
3. 2 in pancreatic acinar cell injury Int J Pancreatol 8 187-201 1:CAS:528:DyaK3MXmtVCqs74%3D 2033328
4. 2 in pancreatic acinar cell damage and possibilities of inhibition: Studies with isolated rat pancreatic acini Pancreas 8 70-9 10.1097/00006676-199301000-00014 1:STN:280:ByyC38njtVc%3D 8419911
5. 2 and phospholipase C on human erythrocytes and ghosts Biochim Biophys Acta 241 925-9 10.1016/ 0005-2736(71)90024-1 1:CAS:528:DyaE3MXltlOisb4%3D 5003696
6. 2 Biochim Biophys Acta 1214 88-96 1:CAS:528:DyaK2cXmtVWmu7k%3D 8068732
7. 2 added exogenously J Biochem 110 163-5 1:CAS:528:DyaK3MXlt1yhu7g%3D 1761509
8. 4 by human leukocytes in vitro Pancreas 9 37-41 10.1097/00006676-199401000-00005 1:STN:280:ByuC2M7islI%3D 8108369
9. 2 on the arachidonic acid cascade Int J Pancreatol 29 69-76 1:CAS:528:DC%2BD38XmtVGit74%3D 11876251
10. K Iizuka K Akahane D Momose M Nakazawa T Tanouchi M Kawamura 1981 Highly selective inhibitors of thromboxane synthetase. 1. Imidazole derivatives J Med Chem 24 1139-48 10.1021/jm00142a005 1:CAS:528:DyaL3MXls1WktL4%3D 7199088
11. 2 in serum Clin Chem 31 714-7 1:CAS:528:DyaL2MXktVamuro%3D 3987000
12. S Valentin O Nordfang C Bregengard P Wildgoose 1993 Evidence that the C-terminus of tissue factor pathway inhibitor (TFPI) is essential for its in vitro and in vivo interaction with lipoproteins Blood Coagul Fibrinolysis 4 713-20 1:CAS:528:DyaK2cXitFemtbo%3D 8292720
13. MO Palmier LJ Hall CM Reisch MK Baldwin AG Wilson TC Wun 1992 Clearance of recombinant tissue factor pathway inhibitor (TFPI) in rabbits Thromb Haemost 68 33-6 1:CAS:528:DyaK38XlsVarsbw%3D 1514170