The synthesis of 3,3-dimethyl-2-(1-aryl-1H-pyrazol-4-yl)-3H-indoles

Journal of Heterocyclic Chemistry

Volumn 43, Issue 6, 2006, Pages 1591-1595

  Baradarani, Mehdi M ^a   Afghan, Arash ^a   Zebarjadi, Farideh ^a   Hasanzadeh, Kamal ^a   Joule, John A ^b  

^a URMIA UNIVERSITY   (Iran)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,3 TRIMETHYLINDOLENINE; 3,3 DIMETHYL 2 (1 PHENYL 1H PYRAZOL 4 YL) 3H INDOLE; 3,3 DIMETHYL 2 (1H PYRAZOL 4 YL) 3H INDOLE; 3,3 DIMETHYL 2 [1 (3 METHYLPHENYL) 1H PYRAZOL 4 YL] 3H INDOLE; 3,3 DIMETHYL 2 [1 (4 METHOXYPHENYL) 1H PYRAZOL 4 YL] 3H INDOLE; 3,3 DIMETHYL 2 [1 (4 NITROPHENYL) 1H PYRAZOL 4 YL] 3H INDOLE; 3,3 DIMETHYL 2 [1 (PYRIDIN 2 YL) 1H PYRAZOL 4 YL] 3H INDOLE; 5 CHLORO 2 [1 (4 CHOROPHENYL) 1H PYRAZOL 4 YL) 3,3 DIMETHYL 3H INDOLE; 5 CHLORO 2,3,3 TRIMETHYLINDOLENINE; 5 CHLORO 3,3 DIMETHYL 2 (1 PHENYL 1H PYRAZOL 4 YL) 3H INDOLE; 5 CHLORO 3,3 DIMETHYL 2 (1H PYRAZOL 4 YL) 3H INDOLE; 5 CHLORO 3,3 DIMETHYL 2 [1 (3 METHYLPHENYL) 1H PYRAZOL 4 YL] 3H INDOLE; 5 CHLORO 3,3 DIMETHYL 2 [1 (PYRIDIN 2 YL) 1H PYRAZOL 4 YL] 3H INDOLE; ALCOHOL; INDOLE DERIVATIVE; PYRAZOLE DERIVATIVE;

ACYLATION; ARTICLE; CHEMICAL MODIFICATION; CHEMICAL REACTION; HEATING; SYNTHESIS;

EID: 33845442215     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570430624     Document Type: Article

References (12)

1. M. C. Friedel, Bull. Soc. Chim. Fr., 11, 1028 (1896).
2. O. Fischer, A. Muller and A. Vilsmeier, J. Prakt. Chem., 109, 69 (1925).
3. A. Vilsmeier and A. Haack, Chem. Ber., 60, 119 (1927);
4. A. Vilsmeier and A. Haack, Bull. Soc. Chim. Fr., 1989 (1962).
5. For an excellent review see: C. Jutz, Adv. Org. Chem., Methods Results, 9, 225 (1976).
6. For some recent contributions see: Y. Cheng, H. B. Yang, B. Liu, O. Meth-Cohn, D. Watkin and S. Humphries, Synthesis, 906 (2003);
7. Y. Cheng, P. Jiao, D. J. Williams and O. Meth-Cohn, Tetrahedron Lett., 40, 6661 (1999).
8. G. Jones and S. P. Stanforth, Org. React., 56, 355 (2000).
9. H. Fritz, Chem. Ber., 92, 1809 (1959).
10. M. Helliwell, A. Afgan, M. M. Baradarani and J. A. Joule, Acta Crystallogr., Sect. E: Cryst. Struct. Commun., E62, o737-o738 (2006).
11. See, for example: V. V. Rozhkov, A. M. Kuvshinov, V. I. Gulevskaya, I. I. Chervin and S. A. Shevelev, Synthesis, 2065 (1999);
12. S. H. Doss, R. M. Mohareb, G. A. Elmegeed and N. A. Luoca, Pharmazie, 58, 607 (2003).