Tissue reactions to bioabsorbable ciprofloxacin-releasing polylactide-polyglycolide 80/20 screws in rabbits' cranial bone

Journal of Materials Science: Materials in Medicine

Volumn 17, Issue 12, 2006, Pages 1315-1322

  Tiainen, Johanna ^a   Soini, Ylermi ^a   Suokas, Esa ^b   Veiranto, Minna ^c   Törmälä, Pertti ^c   Waris, Timo ^a   Ashammakhi, Nureddin ^a,c  

^a OULU UNIVERSITY HOSPITAL   (Finland)

^b Linvatec Biomaterials Ltd ^*  (Finland)

^c TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

HISTOLOGY; MATERIALS SCIENCE; POLARIZATION; POLYMERS; TISSUE;

ADIPOSE TISSUE; CRANIAL BONE; FIBROUS TISSUE; GIANT CELLS; OSTEOBLASTS; TISSUE REACTIONS;

BONE;

BIOMATERIAL; CIPROFLOXACIN; POLYGLACTIN;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL TISSUE; BIODEGRADABLE IMPLANT; BONE SCREW; CONFERENCE PAPER; DEGRADATION; GIANT CELL; HISTOLOGY; INFLAMMATION; MACROPHAGE; MALE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; RABBIT; SKULL; TISSUE REACTION;

ANIMALS; ANTI-INFECTIVE AGENTS; BONE SCREWS; CIPROFLOXACIN; DRUG DELIVERY SYSTEMS; INFLAMMATION; LACTIC ACID; MALE; POLYGLYCOLIC ACID; POLYMERS; RABBITS; SKULL;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 33845434562     PISSN: 09574530     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10856-006-0606-8     Document Type: Conference Paper

References (30)

1. L. NIE, D. NICOLAU, P. TESSIER, H. KOUREA, B. BROWNER and C. NIGHTINGALE, Use of a bioabsorbable polymer for the delivery of ofloxacin during experimental osteomyelitis treatment. J. Orthop. Res. 16 (1998) 76-79.
2. P. BECKER, R. SMITH, R. WILLIAMS and J. DUTKOWSKY, Comparison of antibiotic release from polymethylmethacrylate beads and sponge collagen. J. Orthop. Res. 12 (1994) 737-741.
3. J. CALHOUN and J. MADER, Treatment of osteomyelitis with a biodegradable antibiotic implant. Clin. Orthop. 341 (1997) 206-214.
4. Y. SHINTO, A. UCHIDA, F. KORKUSUZ, N. ARAKI and K. ONO, Calcium hydroxyapatite ceramic used as a delivery system for antibiotics. J. Bone. Joint. Surg. Br. 74-B (1992) 600-604.
5. J. OVERBECK, S. WINCKLER, R. MEFFERT, P. TÖRMÄLÄ, H. SPIEGEL and E. BRUG, Penetration of ciprofloxacin into bone: A new bioabsorbable implant. J. Invest. Surg. 8 (1995) 155-162.
6. E. JACOB, J. SETTERSTRÖM, D. BACH, J. R. HEATH, L. MCNIESH and G. CIERNY, Evaluation of biodegradable ampicillin anhydrate microcapsules for local treatment of experimental staphylococcal osteomyelitis. Clin. Orthop. 267 (1991) 237-244.
7. P. OSTERMANN, S. HENRY and D. SELIGSON, The role of local antibiotic therapy in the management of compound fractures. Clin. Orthop. 295 (1993) 102-111.
8. M. GÜMÜSDERELIOGLU and G. DENIZ, Sustained release of mitomycin-C from poly (DL-lactide)/poly (DL-lactide-coglycolide) films. J. Biomater. Sci. 11 (2000) 1039-1050.
9. C. TEUPE, R. MEFFERT, S. WINCKLER, W. RITZERFELD, P. TÖRMÄ LÄ and E. BRUG, Ciprofloxacin-impregnated poly-L-lactic acid drug carrier. New aspects of a resorbable drug delivery system in local antimicrobial treatment of bone infections. Arch. Orthop. Trauma Surg. 112 (1992) 33-35.
10. J. TIAINEN, M. VEIRANTO, E. SUOKAS, P. TÖRMÄLÄ and T. WARIS, M. NINKOVIC and N. ASHAMMAKHI, Bioabsorbable ciprofloxacin-containing and plain self-reinforced polylactide-polyglycolide 80/20 screws: pull-out strength properties in human cadaver parietal bones. J. Craniofac. Surg. 13 (2002) 427-433.
11. S. LEINONEN, E. SUOKAS, M. VEIRANTO, P. TÖRMÄLÄ, T. WARIS and N. ASHAMMAKHI, Holding power of bioabsorbable ciprofloxacin-containing self-reinforced poly-L/DL-lactide 70/30 bioactive glass 13 miniscrews in human cadaver bone. J. Craniofac. Surg. 13 (2002) 212-218.
12. N. ASHAMMAKHI, Neomembranes: A concept review with special reference to self-reinforced polyglycolide membranes. J. Biomed. Mater. Res. [Appl. Biomater.] 33 (1996) 297-303.
13. B. EPPLEY and M. SADOVE, A comparison of resorbable and metallic fixation in healing of calvarial bone grafts. Plast. Reconstr. Surg. 96 (1995) 316-322.
14. M. VEIRANTO, E. SUOKAS, N. ASHAMMAKHI and P. TÖRMÄLÄ, Novel bioabsorbable antibiotic releasing bone fracture fixation implants. Adv. Exp. Med. Biol. 553 (2004) 197-208.
15. S. -M. NIEMELÄ, I. IKÄHEIMO, M. KOSKELA, M. VEIRANTO, E. SUOKAS, P. TÖRMÄLÄ, T. WARIS, N. ASHAMMAKHI and H. SYRJÄLÄ, Ciprofloxacin-releasing bioabsorbable polymer is superior to titanium in preventing Staphylococcus epidermis attachment and biofilm formation in vitro. J. Biomed. Mater. Res. [Appl. Biomater.] (Accepted).
16. J. KITCHELL and D. WISE, Poly(lactic/glycolic acid) biodegradable drug-polymer matrix systems. Methods Enzymol. 112 (1985) 436-448.
17. S. HUMPHREY, S. MEHTA, A. SEABER and T. VAIL, Pharmacokinetics of a degradable drug delivery system in bone. Clin. Orthop. 349 (1998) 218-224.
18. M. VERT, M. LI, G. SPENLEHAUER and P. GUERIN, Bioresorbability and biocompatibility of aliphatic polyesters. J. Mater. Sci. Mater. Med. 3 (1992) 432-446.
19. P. TÖRMÄLÄ, Biodegradable self-reinforced composite materials; manufacturing structure and mechanical properties. Clin. Mater. 10 (1992) 29-34.
20. W. PIETRZAK, D. SARVER and M VERSTYNEN, Bioabsorbable polymer science for the practicing surgeon. J. Craniofac. Surg. 8 (1997) 87-91.
21. K. KNUUTILA, J. TIAINEN, M. VEIRANTO, E. SUOKAS, T. WARIS, P. TÖRMÄLÄ, O. KAARELA and N. ASHAMMAKHI, Pull-Out Strength Properties of Antibiotic Releasing Tacks in Human Cadaver Bone. Society for Biomaterials Symposium on Biomaterials in Regenerative Medicine: The Advent of Combination Products, Philadelphia, Pennsylvania, USA, 10 (2004) 16-18.
22. P. D. HOLTOM, S. A. PAVKOVIC, P. D. BRAVOS, M. J. PATZAKIS, L. E. SHEPHERD and B. FRENKEL, Inhibitory effects of the quinolone antibiotics trovafloxacin, ciprofloxacin, and levofloxacin on osteoblastic cells in vitro. J. Orthop. Res. 18 (2000) 721-727.
23. T. MICLAU, M. L. EDIN, G. E. LESTER, R. W. LINDSEY and L. E. DAHNERS, Effect of ciprofloxacin on the proliferation of osteoblast-like MG-63 human osteosarcoma cells in vitro. J. Orthop. Res. 16 (1998) 509-512.
24. A. C. PERRY, B. PRPA, M. S. ROUSE, K. E. PIPER, A. D. HANSSEN, J. M. STECKELBERG and R. PATEL, Levofloxacin and trovafloxacin inhibition of experimental fracture-healing. Clin. Orthop. 414 (2003) 95-100.
25. N. ASHAMMAKHI, H. PELTONIEMI, E. WARIS, R. SUURONEN, W. SERLO, M. KELLOMÄKI, P. TÖRMÄLÄ and T. WARIS, Developments in craniomaxillofacial surgery: Use of self-reinforced polyglycolide and polylactide osteofixation devices. Review. Plast. Reconstr. Surg. 108 (2001) 167-180.
26. J. HUNT and D. WILLIAMS, Quantifying the soft tissue response to implanted materials. Biomaterials. 16 (1995) 167-170.
27. J. TIAINEN, Y. SOINI, P. TÖRMÄLÄ, T. WARIS and N. ASHAMMAKHI, Self-reinforced polylactide-polyglycolide 80/20 screws take more than 1 1/2 years to resorb in rabbit cranial bone. J. Biomed. Mater. Res. [Appl. Biomater.] 70B (2004) 49-55.
28. M. HABAL and W. PIETRZAK, Key points in the fixation of the craniofacial skeleton with absorbable biomaterial. J. Craniofac. Surg. 10 (1999) 491-499.
29. N. ASHAMMAKHI, Editorial. Reactions to Biomaterials: the Good, the Bad and Ideas for Developing New Therapeutic Approaches. J. Craniofac. Surg. 16 (2005) 195.
30. G. VINCE, J. HUNT and D. WILLIAMS, Quantitative assessment of the tissue response to implanted biomaterials. Biomaterials. 12 (1991) 731-736.