Purification, sequencing and structural analysis of two acidic phospholipases A2 from the venom of Bothrops insularis (jararaca ilhoa)

Biochimie

Volumn 88, Issue 12, 2006, Pages 1947-1959

  Cogo, José C ^a   Lilla, Sergio ^b   Souza, Gustavo H M F ^c   Hyslop, Stephen ^c   de Nucci, Gilberto ^b,c  

^a Instituto de Pesquisa e Desenvolvimento   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Amino acid sequence; Bothrops insularis; Edema; Mass spectrometry; Myotoxin; Neuromuscular blockade; Phospholipase A2; Phylogenetic analysis

Indexed keywords

CREATINE KINASE; PHOSPHOLIPASE A2; SNAKE VENOM;

ACIDITY; ALPHA HELIX; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BETA CHAIN; CALCIUM BINDING; CHICK; CONTROLLED STUDY; DISULFIDE BOND; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ISOLATION; ENZYME PURIFICATION; ENZYME STRUCTURE; GENE SEQUENCE; GENETIC CONSERVATION; MALE; MASS SPECTROMETRY; MOLECULAR WEIGHT; MOUSE; MUSCLE INJURY; NEUROMUSCULAR BLOCKING; NONHUMAN; PAW EDEMA; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEQUENCE ALIGNMENT; SNAKE; STRUCTURAL HOMOLOGY; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BOTHROPS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CROTALID VENOMS; EDEMA; ISOENZYMES; MALE; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHOLIPASES A; PHYLOGENY; PROTEIN STRUCTURE, SECONDARY; SEQUENCE ALIGNMENT; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

BOTHROPS; BOTHROPS INSULARIS; BOTHROPS JARARACA;

EID: 33845407523     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2006.10.006     Document Type: Article

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