Reduced interference by phenothiazines in amphetamine drug of abuse immunoassays

Archives of Pathology and Laboratory Medicine

Volumn 130, Issue 12, 2006, Pages 1834-1838

  Melanson, Stacy E F ^a   Lee Lewandrowski, Elizabeth ^b   Griggs, David A ^b   Long, William H ^b   Flood, James C ^b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; AMPHETAMINE; CHLORPROMAZINE; EPHEDRINE; METHAMPHETAMINE; PHENOTHIAZINE DERIVATIVE; PHENTERMINE; PROMETHAZINE; PSEUDOEPHEDRINE;

AGITATION; ALLERGY; ARTICLE; CLINICAL ARTICLE; CROSS REACTION; DRUG ABUSE; DRUG DETERMINATION; DRUG URINE LEVEL; EMERGENCY WARD; ENZYME MULTIPLIED IMMUNOASSAY TECHNIQUE; HUMAN; LABORATORY DIAGNOSIS; NAUSEA; RETROSPECTIVE STUDY; VOMITING;

AMPHETAMINE; ANTIBODIES, MONOCLONAL; CENTRAL NERVOUS SYSTEM STIMULANTS; CROSS REACTIONS; ENZYME MULTIPLIED IMMUNOASSAY TECHNIQUE; FALSE POSITIVE REACTIONS; HUMANS; PROMETHAZINE; SUBSTANCE ABUSE DETECTION;

EID: 33845406110     PISSN: 00039985     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Colbert DL. Drug abuse screening with immunoassays: unexpected cross-reactivities and other pitfalls. Br J Biomed Sci. 1994;51:136-146.
2. Poklis A. Unavailability of drug metabolite reference material to evaluate false positive results for monoclonal EMIT dau assay of amphetamine [letter]. Clin Chem. 1992;38:2560.
3. Olsen KM, Gulliksen M, Christopherson AS. Metabolites of chlorpromazine and bromipheniramine may cause false-positive urine amphetamine results with monoclonal EMIT dau Immunoassay [letter]. Clin Chem. 1992;38:611-612.
4. Smith-Kielland A, Olsen KM, Christopherson AS. False-positive results with EMIT II amphetamine/metamphetamine assays in users of common psychotropic drugs [letter]. Clin Chem. 1995;41:951-952.
5. Nixon AL, Long WH, Puopolo PR, Flood JC. Bupropion metabolites produce false-positive urine amphetamine results [letter]. Clin Chem. 1995;41:955-956.
6. Puopolo PR, Volpicelli SA, Johnson DM, Flood JG. Emergency toxicology testing (detection, confirmation, and quantification) of basic drugs in serum by liquid chromatography with photodiode array detection. Clin Chem. 1991;37:2124-2130.
7. TREC Collaborative Group. Rapid tranquillisation for agitated patients in emergency psychiatric rooms: a randomized trial of midazolam versus haloperidol plus promethazine. Br Med J. 2003;327:708-713.
8. Golembiewski JA, O'Brien D. A systematic approach to the management of postoperative nausea and vomiting. J Perianesth Nurs. 2002;17:364-376.
9. Cowings PS, Toscano WB, DeRoshia C, Miller NE. Promethazine as a motion sickness treatment: impact on human performance and mood states. Aviat Space Environ Med. 2000;71:1013-1022.
10. Baselt RC, ed. Disposition of Toxic Drugs and Chemicals in Man, 6th ed. Foster City, NY: Biomedical Publications; 2002:890-891.
11. Verstraete AG, Vander Heyden F. Comparison of the sensitivity and specificity of six immunoassays for the detection of amphetamines in urine. J Anal Toxicol. 2005;29:359-364.
12. Wu AHB, McKay C, Broussard LA, et al. National academy of clinical biochemistry laboratory medicine practice guidelines: recommendations for the use of laboratory tests to support poisoned patients who present to the emergency department. Clin Chem. 2003;49:357-379.