Cardiac diastolic dysfunction in conscious dogs with heart failure induced by chronic coronary microembolization

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 291, Issue 6, 2006, Pages

  Gill, Robert M ^a   Jones, Bonita D ^a   Corbly, Angela K ^a   Wang, Juan ^a   Braz, Julian C ^a   Sandusky, George E ^a   Wang, Jie ^b   Shen, Weiqun ^a  

^a ELI LILLY AND COMPANY   (United States)

^b Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

Author keywords

Coronary embolization; Diastolic stiffness; Plasminogen activator inhibitor 1

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; PLASMINOGEN ACTIVATOR INHIBITOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL EMBOLISM; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; DIASTOLE; DOG; HEART CATHETER; HEART HEMODYNAMICS; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE FIBROSIS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYSTOLE;

ANIMALS; BLOOD PRESSURE; CHRONIC DISEASE; COLLAGEN; DISEASE MODELS, ANIMAL; DOGS; EMBOLISM; FIBROSIS; HEART FAILURE, CONGESTIVE; MALE; MICROCIRCULATION; MICROSPHERES; MYOCARDIAL CONTRACTION; MYOCARDIUM; PLASMINOGEN ACTIVATOR INHIBITOR 1; VENTRICULAR DYSFUNCTION, LEFT;

EID: 33845404292     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00052.2006     Document Type: Article

References (20)

1. Alexander CM and Werb Z. Proteinases and extracellular matrix remodeling. Curr Opin Cell Biol 1: 974-982, 1989.
2. Burkhoff D, Maurer MS, and Packer M. Heart failure with a normal ejection fraction: is it really a disorder of diastolic function? Circulation 107: 656-658, 2003.
3. Burkhoff D, Mirsky I, and Suga H. Assessment of systolic and diastolic ventricular properties via pressure-volume analysis: a guide for clinical, translational, and basic researchers. Am J Physiol Heart Circ Physiol 289: H501-H512, 2005.
4. Covell JW. Factors influencing diastolic function. Possible role of the extracellular matrix. Circulation 81, Suppl 2: III155-III158, 1990.
5. Gill RM, Jones BD, Corbly AK, Ohad DG, Smith GD, Sandusky GE, Christe ME, Wang J, and Shen W. Exhaustion of the Frank-Starling mechanism in conscious dogs with heart failure induced by chronic coronary microembolization. Life Sci 79: 536-544, 2006.
6. He KL, Dickstein M, Sabbah HN, Yi GH, Gu A, Maurer M, Wei CM, Wang J, and Burkhoff D. Mechanisms of heart failure with well preserved ejection fraction in dogs following limited coronary microembolization. Cardiovasc Res 64: 72-83, 2004.
7. Kass DA, Bronzwaer JG, and Paulus WJ. What mechanisms underlie diastolic dysfunction in heart failure? Circ Res 94: 1533-1542, 2004.
8. Komamura K, Shannon RP, Pasipoularides A, Ihara T, Lader AS, Patrick TA, Bishop SP, and Vatner SF. Alterations in left ventricular diastolic function in conscious dogs with pacing-induced heart failure. J Clin Invest 89: 1825-1838, 1992.
9. Mirsky I and Pasipoularides A. Clinical assessment of diastolic function. Prog Cardiovasc Dis 32: 291-318, 1990.
10. Mishima T, Tanimura M, Suzuki G, Todor A, Sharov VG, Goldstein S, and Sabbah HN. Effects of long-term therapy with bosentan on the progression of left ventricular dysfunction and remodeling in dogs with heart failure. J Am Coll Cardiol 35: 222-229, 2000.
11. Perlini S, Soffiantino F, Farilla C, Solda P, Calciati A, Paro M, Finardi G, and Bernardi L. Load dependence of isovolumic relaxation in intact heart: facts or artifacts? Cardiovasc Res 22: 47-54, 1988.
12. Sabbah HN, Stein PD, Kono T, Gheorghiade M, Levine TB, Jafri S, Hawkins ET, and Goldstein S. A canine model of chronic heart failure produced by multiple sequential coronary microembolizations. Am J Physiol Heart Circ Physiol 260: H1379-H1384, 1991.
13. Sabbah HN, Sharov VG, Lesch M, and Goldstein S. Progression of heart failure: a role for interstitial fibrosis. Mol Cell Biochem 147: 29-34, 1995.
14. Shannon RP, Komamura K, Stambler BS, Bigaud M, Manders WT, and Vatner SF. Alterations in myocardial contractility in conscious dogs with dilated cardiomyopathy. Am J Physiol Heart Circ Physiol 260: H1903-H1911, 1991.
15. Shen W, Spindler M, Higgins MA, Jin N, Gill RM, Bloem LJ, Ryan TP, and Ingwall JS. The fall in creatine levels and creatine kinase isozyme changes in the failing heart are reversible: complex post-transcriptional regulation of the components of the CK system. J Mol Cell Cardiol 39: 537-544, 2005.
16. Shen W, Xu X, Ochoa M, Zeballos GA, Stewart JM, and Hintze TH. Contribution of the ventricles and the atrial appendages to the elevation of plasma atrial natriuretic factor (ANF) during pacing-induced heart failure in conscious dogs. Basic Res Cardiol 91: 319-328, 1996.
17. Suzuki G, Morita H, Mishima T, Sharov VG, Todor A, Tanhehco EJ, Rudolph AE, McMahon EG, Goldstein S, and Sabbah HN. Effects of long-term monotherapy with eplerenone, a novel aldosterone blocker, on progression of left ventricular dysfunction and remodeling in dogs with heart failure. Circulation 106: 2967-2972, 2002.
18. Takeshita K, Hayashi M, Iino S, Kondo T, Inden Y, Iwase M, Kojima T, Hirai M, Ito M, Loskutoff DJ, Saito H, Murohara T, and Yamamoto K. Increased expression of plasminogen activator inhibitor-1 in cardiomyocytes contributes to cardiac fibrosis after myocardial infarction. Am J Pathol 164: 449-456, 2004.
19. Yi GH, Burkhoff D, Zhang H, Zhu SM, Zwas D, and Wang J. Hemodynamic effects of a calcium channel promoter, BAY y 5959, are preserved after chronic administration in ischemic heart failure in conscious dogs. J Pharmacol Exp Ther 286:760-766, 1998.
20. Zile MR, Baicu CF, and Gaasch WH. Diastolic heart failure - abnormalities in active relaxation and passive stiffness of the left ventricle. N Engl J Med 350: 1953-1959, 2004.