Activation of microglia by Borna disease virus infection: In vitro study

Journal of Virology

Volumn 80, Issue 24, 2006, Pages 12141-12148

  Ovanesov, Mikhail V ^a,b   Sauder, Christian ^b   Rubin, Steven A ^b   Richt, Jürgen ^c   Nath, Avindra ^d   Carbone, Kathryn M ^b   Pletnikov, Mikhail V ^a,b,e  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^c NATIONAL ANIMAL DISEASE CENTER   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; ASTROCYTE; BORNA DISEASE; BORNA DISEASE VIRUS; CELL ACTIVATION; CELL PROLIFERATION; CELL SHAPE; CELL STRUCTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; IN VITRO STUDY; MICROGLIA; NERVE CELL NECROSIS; NEUROTOXICITY; NEWBORN; NEWBORN INFECTION; NONHUMAN; PERSISTENT VIRUS INFECTION; PRIORITY JOURNAL; RAT;

ANIMALS; BORNA DISEASE; BORNA DISEASE VIRUS; CELLS, CULTURED; CYTOTOXICITY TESTS, IMMUNOLOGIC; HISTOCOMPATIBILITY ANTIGENS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-10; INTERLEUKIN-1BETA; MICROGLIA; RATS; TUMOR NECROSIS FACTOR-ALPHA;

BORNA DISEASE VIRUS;

EID: 33845397110     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01648-06     Document Type: Article

References (46)

1. Bi, Z., M. Barna, T. Komatsu, and C. S. Reiss. 1995. Vesicular stomatitis virus infection of the central nervous system activates both innate and acquired immunity. J. Virol. 69:6466-6472.
2. Block, M. L., and J. S. Hong. 2005. Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism. Prog. Neurobiol. 76:77-98.
3. Bode, L., and H. Ludwig. 2003. Borna disease virus infection, a human mental-health risk. Clin. Microbiol. Rev. 16:534-545.
4. Cabarrocas, J., J. Bauer, E. Piaggio, R. Liblau, and H. Lassmann. 2003. Effective and selective immune surveillance of the brain by MHC class I-restricted cytotoxic T lymphocytes. Eur. J. Immunol. 33:1174-1182.
5. Carbone, K. M., B. D. Trapp, J. W. Griffin, C. S. Duchala, and O. Narayan. 1989. Astrocytes and Schwann cells are virus-host cells in the nervous system of rats with Borna disease. J. Neuropathol. Exp. Neurol. 48:631-644.
6. Carbone, K. M., S. W. Park, S. A. Rubin, R. W. Waltrip II, and G. B. Vogelsang. 1991. Borna disease: association with a maturation defect in the cellular immune response. J. Virol. 65:6154-6164.
7. Carbone, K. M., S. A. Rubin, A. M. Sierra-Honigmann, and H. M. Lederman. 1993. Characterization of a glial cell line persistently infected with borna disease virus (BDV): influence of neurotrophic factors on BDV protein and RNA expression. J. Virol. 67:1453-1460.
8. Chen, J., Y. Zhou, S. Mueller-Steiner, L. F. Chen, H. Kwon, S. Yi, L. Mucke, and L. Gan. 2005. SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-κB signaling. J. Biol. Chem. 280:40364-40374.
9. Conant, K., M. Ma, A. Nath, and E. O. Major. 1996. Extracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-κB binding and protein kinase C activity in primary human astrocytes. J. Virol. 70:1384-1389.
10. Cubitt, B., C. Oldstone, and J. C. de la Torre. 1994. Sequence and genome organization of Borna disease virus. J. Virol. 68:1382-1396.
11. De, S. R., M. A. Ajmone-Cat, A. Nicolini, and L. Minghetti. 2002. Expression of phosphatidylserine receptor and down-regulation of pro-inflammatory molecule production by its natural ligand in rat microglial cultures. J. Neuropathol. Exp. Neurol. 61:237-244.
12. de la Torre, J. C. 2002. Bornavirus and the brain. J. Infect. Dis. 186(Suppl. 2):S241-S247.
13. De Simone, R., M. A. Ajmone-Cat, P. Tirassa, and L. Minghetti. 2003. Apoptotic PC12 cells exposing phosphatidylserine promote the production of anti-inflammatory and neuroprotective molecules by microglial cells. J. Neuropathol. Exp. Neurol. 62:208-216.
14. Dopp, J. M., A. Mackenzie-Graham, G. C. Otero, and J. E. Merrill. 1997. Differential expression, cytokine modulation, and specific functions of type-1 and type-2 tumor necrosis factor receptors in rat glia. J. Neuroimmunol. 75:104-112.
15. Eddleston, M., and L. Mucke. 1993. Molecular profile of reactive astrocytes-implications for their role in neurologic disease. Neuroscience 54:15-36.
16. Eisenman. L. M., R. Brothers, M. H. Tran, R. B. Kean, G. M. Dickson, B. Dietzschold, and D. C. Hooper. 1999. Neonatal Borna disease virus infection in the rat causes a loss of Purkinje cells in the cerebellum. J. Neurovirol. 5:181-189.
17. Faustmann, P. M., C. G. Haase, S. Romberg, D. Hinkerohe, D. Szlachta, D. Smikalla, D. Krause, and R. Dermietzel. 2003. Microglia activation influences dye coupling and Cx43 expression of the astrocytic network. Glia 42:101-108.
18. Gonzalez-Dunia, D., R. Volmer, D. Mayer, and M. Schwemmte. 2005. Borna disease virus interference with neuronal plasticity. Virus Res. 111:224-234.
19. Haas, B., H. Becht, and R. Rott. 1986. Purification and properties of an intranuclear virus-specific antigen from tissue infected with Borna disease virus. J. Gen. Virol. 67:235-241.
20. Hans, A., J. J. Bajramovic, S. Syan, E. Perret, I. Dunia, M. Brahic, and D. Gonzalez-Dunia. 2004. Persistent, noncytolytic infection of neurons by Borna disease virus interferes with ERK 1/2 signaling and abrogates BDNF-induced synaptogenesis. FASEB J. 18:863-865.
21. Herzog, S., and R. Rott. 1980. Replication of Borna disease virus in cell cultures. Med. Microbiol. Immunol. 168:153-158.
22. Hornig, M., H. Weissenbock, N. Horscroft, and W. I. Lipkin. 1999. An infection-based model of neurodevelopmental damage. Proc. Natl. Acad. Sci. USA 96:12102-12107.
23. Howard, L. M., A. J. Miga, C. L. Vanderlugt, M. C. Dal Canto, J. D. Laman, R. J. Noelle, and S. D. Miller. 1999. Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis. J. Clin. Investig. 103:281-290.
24. Huygen, I. C. 1970. Reaction of nitrogen dioxide with Griess type reagents. Anal. Chem. 42:407-409.
25. Kim, W. G., R. P. Mohney, B. Wilson, G. H. Jeohn, B. Liu, and J. S. Hong. 2000. Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia. J. Neurosci. 20:6309-6316.
26. Mander, P. K., A. Jekabsone, and G. C. Brown. 2006. Microglia proliferation is regulated by hydrogen peroxide from NADPH oxidase. J. Immunol. 176:1046-1052.
27. Mattson, M. P., B. Cheng, D. Davis, K. Bryant, I. Lieberburg, and R. E. Rydel. 1992. β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J. Neurosci. 12:376-389.
28. Meeker, R. B., Y. Azuma, D. C. Bragg, R. V. English, and M. Tompkins. 1999. Microglial proliferation in cortical neural cultures exposed to feline immunodeficiency virus. J. Neuroimmunol. 101:15-26.
29. Nakamichi, K., M. Saiki, M. Sawada, Y. Yamamuro, K. Morimoto, and I. Kurane. 2005. Double-stranded RNA stimulates chemokine expression in microglia through vacuolar pH-dependent activation of intracellular signaling pathways. J. Neurochem. 95:273-283.
30. Pauli, G., and H. Ludwig. 1985. Increase of virus yields and releases of Borna disease virus from persistently infected cells. Virus Res. 2:29-33.
31. Pleschka, S., P. Staeheli, J. Kolodziejek, J. A. Richt, N. Nowotny, and M. Schwemmle. 2001. Conservation of coding potential and terminal sequences in four different isolates of Borna disease virus. J. Gen. Virol. 82:2681-2690.
32. Polazzi, E., T. Gianni, and A. Contestabile. 2001. Microglial cells protect cerebellar granule neurons from apoptosis: evidence for reciprocal signaling. Glia 36:271-280.
33. Rauer, M., A. Pagenstecher, J. Schulte-Monting, and C. Sauder. 2002. Upregulation of chemokine receptor gene expression in brains of Borna disease virus (BDV)-infected rats in the absence and presence of inflammation. J. Neurovirol. 8:168-179.
34. Richt, J. A., and L. Stitz. 1992. Borna disease virus-infected astrocytes function in vitro as antigen-presenting and target cells for virus-specific CD4-bearing lymphocytes. Arch. Virol. 124:95-109.
35. Ringheim, G. E. 1995. Mitogenic effects of interleukin-5 on microglia. Neurosci. Lett. 201:131-134.
36. Rock, R. B., G. Gekker, S. Hu, W. S. Sheng, M. Cheeran, J. R. Lokensgard, and P. K. Peterson. 2004. Role of microglia in central nervous system infections. Clin. Microbiol. Rev. 17:942-964.
37. Rohl, C., and J. Sievers. 2005. Microglia is activated by astrocytes in trimethyltin intoxication. Toxicol. Appl. Pharmacol. 204:36-45.
38. Sauder, C., and J. C. de la Torre. 1999. Cytokine expression in the rat central nervous system following perinatal Borna disease virus infection. J. Neuroimmunol. 96:29-45.
39. Sawada, M., N. Kondo, A. Suzumura, and T. Marunouchi. 1989. Production of tumor necrosis factor-alpha by microglia and astrocytes in culture. Brain Res. 491:394-397.
40. Si, Q., Y. Nakamura, and K. Kataoka. 2000. A serum factor enhances production of nitric oxide and tumor necrosis factor-alpha from cultured microglia. Exp. Neurol. 162:89-97.
41. Sola, C., C. Casal, J. M. Tusell, and J. Serratosa. 2002. Astrocytes enhance lipopolysaccharide-induced nitric oxide production by microglial cells. Eur. J. Neurosci. 16:1275-1283.
42. Streit, W. J., and G. W. Kreutzberg. 1987. Lectin binding by resting and reactive microglia. J. Neurocytol. 16:249-260.
43. Streit, W. J. 2002. Microglia as neuroprotective, immunocompetent cells of the CNS. Glia 40:133-139.
44. Weissenböck, H., M. Hornig, W. F. Hickey, and W. I. Lipkin. 2000. Microglial activation and neuronal apoptosis in Bornavirus infected neonatal Lewis rats. Brain Pathol. 10:260-272.
45. Zocher, M., S. Czub, J. Schulte-Monting, J. C. de La Torreqq, and C. Sauder. 2000. Alterations in neurotrophia and neurotrophin receptor gene expression patterns in the rat central nervous system following perinatal Borna disease virus infection. J. Neurovirol. 6:462-477.
46. Zuo, J., S. A. Stohlman, J. B. Hoskin, D. R. Hinton, R. Atkinson, and C. C. Bergmann. 2006. Mouse hepatitis virus pathogenesis in the central nervous system is independent of IL-15 and natural killer cells. Virology 350:206-215.