A CD34+ human cell line model of myeloid dendritic cell differentiation: Evidence for a CD14+CD11b+ Langerhans cell precursor

Journal of Leukocyte Biology

Volumn 80, Issue 6, 2006, Pages 1337-1344

  Santegoets, Saskia J A M ^a   Masterson, Allan J ^a   Van Der Sluis, Pieter C ^a   Lougheed, Sinéad M ^a   Fluitsma, Donna M ^a   Van Den Eertwegh, Alfons J M ^a   Pinedo, Herbert M ^a   Scheper, Rik J ^a   De Gruijl, Tanja D ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Acute myeloid leukemia; Cytokines; MUTZ 3; Progenitor

Indexed keywords

CD11B ANTIGEN; CD14 ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; LANGERIN;

ARTICLE; BONE MARROW CELL; CD34 SELECTION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SUBPOPULATION; DENDRITIC CELL; HUMAN; HUMAN CELL; LANGERHANS CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL;

ANTIGENS, CD; ANTIGENS, CD11B; ANTIGENS, CD14; ANTIGENS, CD34; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOPLASMIC GRANULES; GENE EXPRESSION REGULATION; HUMANS; LANGERHANS CELLS; LECTINS, C-TYPE; MANNOSE-BINDING LECTINS; MODELS, IMMUNOLOGICAL; MYELOID PROGENITOR CELLS;

EID: 33845387051     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0206111     Document Type: Article

References (30)

1. Banchereau, J., Briere, F., Caux, C., Davoust, J., Lebecque, S., Liu, Y. J., Pulendran, B., Palucka, K. (2000) Immunobiology of dendritic cells. Annu. Rev. Immunol. 18, 767-811.
2. Granucci, F., Foti, M., Ricciardi-Castagnoli, P. (2005) Dendritic cell biology. Adv. Immunol. 88, 193-233.
3. Ardavin, C., Martinez del Hoyo, G., Martin, P., Anjuere, F., Arias, C. F., Marin, A. R., Ruiz, S., Parrillas, V., Hernandez, H. (2001) Origin and differentiation of dendritic cells. Trends Immunol. 22, 691-700.
4. Ferrero, E., Bondanza, A., Leone, B. E., Manici, S., Poggi, A., Zocchi, M. R. (1998) CD14+ CD34+ peripheral blood mononuclear cells migrate across endothelium and give rise to immunostimulatory dendritic cells. J. Immunol. 160, 2675-2683.
5. Rondelli, D., Lemoli, R. M., Ratta, M., Fogli, M., Re, F., Curti, A., Arpinati, M., Tura, S. (1999) Rapid induction of CD40 on a subset of granulocyte colony-stimulating factor-mobilized CD34(+) blood cells identifies myeloid-committed progenitors and permits selection of nonimmunogenic CD40(-) progenitor cells. Blood 94, 2293-2300.
6. Arrighi, J. F., Hauser, C., Chapuis, B., Zubler, R. H., Kindler, V. (1999) Long-term culture of human CD34(+) progenitors with FLT3-ligand, thrombopoietin, and stem cell factor induces extensive amplification of a CD34(-)CD14(-) and a CD34(-) CD14(+) dendritic cell precursor. Blood 93, 2244-2252.
7. Schibler, K., Georgelas, A., Rigaa, A. (2002) Developmental biology of the dendritic cell system. Acta Paediatr. Suppl. 91, 9-16.
8. Caux, C., Vanbervliet, B., Massacrier, C., Dezutter-Dambuyant, C., de Saint-Vis, B., Jacquet, C., Yoneda, K., Imamura, S., Schmitt, D., Banchereau, J. (1996) CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF α. J. Exp. Med. 184, 695-706.
9. Caux, C., Massacrier, C., Vanbervliet, B., Dubois, B., Durand, I., Cella, M., Lanzavecchia, A., Banchereau, J. (1997) CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to granulocyte-macrophage colony-stimulating factor plus tumor necrosis factor α: II. Functional analysis. Blood 90, 1458-1470.
10. Caux, C., Massacrier, C., Dubois, B., Valladeau, J., Dezutter-Dambuyant, C., Durand, I., Schmitt, D., Saeland, S. (1999) Respective involvement of TGF-β and IL-4 in the development of Langerhans cells and non-Langerhans dendritic cells from CD34+ progenitors. J. Leukoc. Biol. 66, 781-791.
11. Jaksits, S., Kriehuber, E., Charbonnier, A. S., Rappersberger, K., Stingl, G., Maurer, D. (1999) CD34+ cell-derived CD14+ precursor cells develop into Langerhans cells in a TGF-β 1-dependent manner. J. Immunol. 163, 4869-4877.
12. Larregina, A. T., Morelli, A. E., Spencer, L. A., Logar, A. J., Watkins, S. C., Thomson, A. W., Falo Jr., L. D. (2001) Dermal-resident CD14+ cells differentiate into Langerhans cells. Nat. Immunol. 2, 1151-1158.
13. ONeill, H. C., Wilson, H. L. (2004) Limitations with in vitro production of dendritic cells using cytokines. J. Leukoc. Biol. 75, 600-603.
14. Masterson, A. J., Sombroek, C. C., de Gruijl, T. D., Graus, Y. M., van der Vliet, H. J., Lougheed, S. M., van den Eertwegh, A. J. M., Pinedo, H. M., Scheper, R. J. (2002) MUTZ-3, a human cell line model for the cytokine-induced differentiation of dendritic cells from CD34+ precursors. Blood 100, 701-703.
15. Berges, C., Naujokat, C., Tinapp, S., Wieczorek, H., Höh, A., Sadeghi, M., Opelz, G., Volker, D. (2005) A cell line model for the differentiation of human dendritic cells. Biochem. Biophys. Res. Commun. 333, 896-907.
16. Platzer, B., Jörgl, A., Taschner, S., Höcher, B., Strobl, H. (2004) RelB regulates human dendritic cell subset development by promoting monocyte intermediates. Blood 104, 3655-3663.
17. Hu, Z. B., Ma, W., Zaborski, M., MacLeod, R., Quentmeier, H., Drexler, H. G. (1996) Establishment and characterization of two novel cytokine-responsive acute myeloid and monocytic leukemia cell lines, MUTZ-2 and MUTZ-3. Leukemia 10, 1025-1040.
18. Quentmeier, H., Duschl, A., Hu, Z. B., Schnarr, B., Zaborski, M., Drexler, H. G. (1996) MUTZ-3, a monocytic model cell line for interleukin-4 and lipopolysaccharide studies. Immunology 89, 606-612.
19. Dzionek, A., Fuchs, A., Schmidt, P., Cremer, S., Zysk, M., Miltenyi, S., Buck, D. W., Schmitz, J. (2000) BDCA-2, BDCA-3, and BDCA-4: three markers for distinct subsets of dendritic cells in human peripheral blood. J. Immunol. 165, 6037-6046.
20. Wilson, H. L., O'Neill, H. C. (2003) Identification of differentially expressed genes representing dendritic cell precursors and their progeny Blood 102, 1661-1669.
21. Ni, K., O'Neill, H. C. (1998) Hemopoiesis in long-term stroma-dependent cultures from lymphoid tissue: production of cells with myeloid/dendritic characteristics. In Vitro Cell. Dev. Biol. Anim. 34, 298-307.
22. Wilson, H. L., Ni, K., O'Neill, H. C. (2000) Identification of progenitor cells in long-term spleen stromal cultures that produce immature dendritic cells. Proc. Natl. Acad. Sci. USA 97, 4784-4789.
23. Tsuchiyama, J., Mori, M., Okada, S. (1995) Murine spleen stromal cell line SPY3-2 maintains long-term hematopoiesis in vitro. Blood 85, 3107-3116.
24. Ni, K., O'Neill, H. C. (1997) Long-term stromal cultures produce dendritic-like cells. Br. J. Haematol. 97, 710-725.
25. Quentmeier, H., Zaborski, M., Drexler, H. G. (1997) The human bladder carcinoma cell line 5637 constitutively secretes functional cytokines. Leuk. Res. 21, 343-350.
26. Relloso, M., Puig-Kroger, A., Pello, O. M., Rodriguez-Fernandez, J. L., de la Rosa, G., Longo, N., Navarro, J., Munoz-Fernandez, M. A., Sanchez-Mateos, P., Corb, A. L. (2002) DC-SIGN (CD209) expression is IL-4 dependent and is negatively regulated by IFN, TGF-β, and anti-inflammatory agents. J. Immunol. 168, 2634-2643.
27. Larsson, K., Lindstedt, M., Borrebeck, C. A. K. (2006) Functional and transcriptional profiling of MUTZ-3, a myeloid cell line acting as a model for dendritic cells. Immunology 117, 156-166.
28. Heinz, L. X., Platzer, B., Reisner, P. M., Jorgl, A., Taschner, S., Gobel, F., Strobl, H. (2005) Differential involvement of PU.1 and Id2 downstream of TGFα1 during Langerhans cell commitment. Blood 107, 1445-1453.
29. Geissmann, F., Prost, C., Monnet, J-P., Dy, M., Brousse, N., Hermine, O. (1998) Transforming growth factor β1, in the presence of granulocyte/macrophage colony-stimulating factor and interleukin 4, induces differentiation of human peripheral blood monocytes into dendritic Langerhans cells. J. Exp. Med. 187, 961-966.
30. Mohamadzadeh, M., Berard, F., Essert, G., Chalouni, C., Pulendran, B., Davoust, J., Bridges, G., Palucka, A. K., Banchereau, J. (2001) Interleukin 15 skews monocyte differentiation into dendritic cells with features of Langerhans cells. J. Exp. Med. 194, 1013-1020.