Pharmacokinetic and phase II study of heated intraoperative intraperitoneal melphalan

Cancer Chemotherapy and Pharmacology

Volumn 59, Issue 2, 2007, Pages 151-155

  Sugarbaker, Paul H ^a   Stuart, O Anthony ^a  

^a WASHINGTON CANCER INSTITUTE   (United States)

Author keywords

Carcinomatosis; Intraoperative chemotherapy; Intraperitoneal chemotherapy; Peritoneal surface malignancy; Pharmacokinetics

Indexed keywords

ALKYLATING AGENT; DIALYSIS FLUID; GLUCOSE; MELPHALAN;

ADULT; ANASTOMOSIS LEAKAGE; AREA UNDER THE CURVE; ARTICLE; BONE MARROW SUPPRESSION; CARCINOMATOUS PERITONITIS; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARTMENT SYNDROME; CYTOREDUCTIVE SURGERY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DOSE REDUCTION; DRUG EFFECT; DRUG EFFICACY; DRUG EXCRETION; DRUG PERITONEAL FLUID LEVEL; DRUG TUMOR LEVEL; DRUG URINE LEVEL; FEMALE; HEATING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; INTESTINE FISTULA; INTRAOPERATIVE PERIOD; LOWER LEG MUSCLE COMPARTMENT SYNDROME; MALE; MINIMAL RESIDUAL DISEASE; OUTCOME ASSESSMENT; PANCREATITIS; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; RECOMMENDED DRUG DOSE; SINGLE DRUG DOSE; URINARY EXCRETION;

ADULT; AGED; ANTINEOPLASTIC AGENTS, ALKYLATING; AREA UNDER CURVE; ASCITIC FLUID; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HEATING; HUMANS; INFUSIONS, PARENTERAL; MALE; MELPHALAN; MIDDLE AGED; NEOPLASM, RESIDUAL; PERITONEAL NEOPLASMS; TIME FACTORS;

EID: 33845366989     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-006-0238-1     Document Type: Article

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