A type II-collagen derived peptide and its nitrated form as new markers of inflammation and cartilage degradation in equine osteochondral lesions

Research in Veterinary Science

Volumn 82, Issue 1, 2007, Pages 68-75

  Gangl, M ^a   Serteyn, D ^a,b   Lejeune, J Ph ^b   Schneider, N ^b   Grulke, S ^a   Peters, F ^a   Vila, T ^c   Deby Dupont, G ^a   Deberg, M ^a   Henrotin, Y ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b European Horse Center   (Belgium)

^c CLINIQUE VÉTÉRINAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 2; MYELOPEROXIDASE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE;

ARTHROSCOPY; ARTICLE; CARTILAGE DEGENERATION; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVITY; FEMALE; HORSE DISEASE; MALE; NITRATION; NONHUMAN; OSTEOCHONDROSIS; PROTEIN BLOOD LEVEL; SCORING SYSTEM;

ANIMALS; BIOLOGICAL MARKERS; CARTILAGE DISEASES; COLLAGEN TYPE II; FEMALE; HORSE DISEASES; HORSES; INFLAMMATION; MALE; NITRO COMPOUNDS;

EQUIDAE;

EID: 33845361346     PISSN: 00345288     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rvsc.2006.03.008     Document Type: Article

References (44)

1. Attur M.G., Dave M., Akamatsu M., Katoh M., and Amin A.R. Osteoarthritis or osteoarthrosis: the definition of inflammation becomes a semantic issue in the genomic era of molecular medicine. Osteoarthritis Cartilage 10 (2002) 1-4
2. Ayral X., Dougados M., Listrat V., Bonvarlet J.-P., Simonnet J., and Amor B. Arthroscopic evaluation of chondropathy in osteoarthritis of the knee. Journal of Rheumatology 23 (1996) 698-706
3. Baldus S., Eiserich J.P., Brennan M.-L., Jackson R.M., Alexander C.B., and Freeman B.A. Spatial mapping of pulmonary and vascular nitrotyrosine reveals the pivotal role of myeloperoxidase as a catalyst for tyrosine nitration in inflammatory diseases. Free Radical Biology & Medicine 33 (2002) 1010-1019
4. Billingshurst R.C., Buxton E.M., Edwards M.G., McGraw M.S., and McIlwraith C.W. Use of an antineoepitope antibody for identification of type-II collagen degradation in equine articular cartilage. American Journal of Veterinary Research 62 (2001) 1031-1039
5. Billingshurst R.C., Brama P.A.J., Van Weeren P.R., Knowlton M.S., and McIlwraith C.W. Significant exercise-related changes in the serum levels of two biomarkers of collagen metabolism in young horses. Osteoarthritis Cartilage 11 (2003) 760-769
6. Billingshurst R.C., Brama P.A.J., Van Weeren P.R., Knowlton M.S., and McIlwraith C.W. Evaluation of serum concentrations of biomarkers of skeletal metabolism and results of radiography as indicators of severity of osteochondrosis in foals. American Journal of Veterinary Research 65 (2004) 143-150
7. Brennan M.-L., Wu W., Fu X., Shen Z., Song W., Frost H., Vadseth C., Narine L., Lenkiewicz E., Borchers M.T., Lusis A.J., and Hazen S.L. A tale of two controversies. Defining both the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase-deficient mice, and the nature of peroxidase-generated reactive nitrogen species. Journal of Biological Chemistry 277 (2002) 17415-17427
8. Bridges C.H., and Harris E.D. Experimentally induced cartilaginous fractures (osteochondrosis dissecans) in foals fed low-copper diets. Journal of The American Veterinary Medical Association 193 (1988) 215-221
9. Caron J.P. Osteoarthritis. In: Ross M.W., and Dyson S.J. (Eds). Diagnosis and Management of Lameness in the Horse. first ed. (2003), WB Saunders Co, Philadelphia 572-591
10. Deberg M., Labasse A., Christgau S., Henriksen D., Reginster J.Y., and Henrotin Y.E. Cartilage degradation and oxidative damage in osteoarthritic and rheumatoid arthritic patients. Osteoarthritis Cartilage 11 (2003) 36
11. 2) for studying oxidative-related type II collagen network degradation in patients with osteoarthritis and rheumatoid arthritis. Osteoarthritis Cartilage 13 (2005) 258-265
12. Dik K.J., Enzerink E., and Van Weeren P.R. Radiographic development of osteochondral abnormalities, in the hock and stifle of Dutch warmblood foals, from age 1 to 11 months. Equine Veterinary Journal Supplement 31 (1999) 9-15
13. Dimock A.N., Siciliano P.D., and McIlwraith C.W. Evidence supporting an increased presence of reactive oxygen species in the diseased equine joint. Equine Veterinary Journal 32 (2000) 439-443
14. Douglas J. Pathogenesis of osteochondrosis. In: Ross M.W., and Dyson S.J. (Eds). Diagnosis and Management of Lameness in the Horse. first ed. (2003), WB Saunders Co, Philadelphia 534-543
15. Frisbie D.D., Al-Sobayil F., Billingshurst R.C., and McIlwraith C.W. Serum Biomakers distinguish exercise from osteoarthritic pathology. Osteoarthritis Cartilage Supplement 10 (2002) S53
16. Garnero P., Rousseau J.-C., and Delmas P.D. Molecular basis and clinical use of biochemical markers of bone, cartilage, and synovium in joint diseases. Arthritis Rheumatism 43 (2000) 953-968
17. Gaut J.P., Byun J., Tran H.D., Lauber W.M., Carroll J.A., Hotchkiss R.S., Belaaouaj A., and Heinecke J.W. Myeloperoxidase produces nitrating oxidants in vivo. Journal of Clinical Investigation 109 (2002) 1311-1319
18. Henrotin Y.E., Deby-Dupont G.P., Deby C., De Bruyn M., Lamy M., and Franchimont P. Production of active oxygen species by isolated human chondrocytes. British Journal of Rheumatology 32 (1993) 562-567
19. 2 production by human chondrocytes. Journal of Rheumatology 25 (1998) 1595-1601
20. Henrotin Y.E., Bruckner P., and Pujol J.P.L. The role of active oxygen species in homeostasis and degradation of cartilage. Osteoarthritis Cartilage 11 (2003) 747-755
21. Henrotin Y.E., Deberg M., Dubuc J.E., Quettier E., Christgau S., and Reginster J.Y. Type II collagen peptides for measuring cartilage degradation. Biorheology 41 (2004) 543-547
22. Henson F.M.D., Davies M.E., Schofield P.N., and Jeffcott L.B. Expression of types II, VI and X collagen in equine growth cartilage during development. Equine Veterinary Journal 28 (1996) 189-198
23. Hurtig M., Green S.L., Dobson H., Mikuni-Takagaki Y., and Choi J. Correlative study of defective cartilage and bone growth in foals fed a low-copper diet. Equine Veterinary Journal Supplement 16 (1993) 66-73
24. Jeffcott L.B. Osteochondrosis in the horse-searching for the key to pathogenesis. Equine Veterinary Journal 23 (1991) 331-338
25. Jeffcott L.B., and Henson F.M.D. Studies on growth cartilage in the horse and their application to aetiopathogenesis of dyschondroplasia (Osteochondrosis). Veterinary Journal 156 (1998) 177-192
26. 4 receptor antagonist LY293111Na. Inflammation Research 51 (2002) 541-550
27. Laverty S., O'Kouneff S., Ionescu M., Reiner A., Pidoux I., Webber C., Rossier Y., Billingshurst R.C., and Poole A.R. Excessive degradation of type II collagen in articular cartilage in equine osteochondrosis. Journal of Orthopaedic Research 20 (2002) 1282-1289
28. Lillich J.D., Bertone A.L., Malemud C.J., Weisbrode S.E., Ruggles A.J., and Stevenson S. Biochemical, histochemical and immunohistochemical characterization of distal tibial osteochondrosis in horses. American Journal of Veterinary Research 58 (1997) 89-98
29. Lohmander L.S. What is the current status of biochemical markers in the diagnosis, prognosis and monitoring of osteoarthritis?. Baillière's Clinical Rheumatology 11 (1997) 711-726
30. McIlwraith C.W. Diagnostic and surgical arthroscopy of the metacarpophalangeal and metatarsophalangeal joints, of the femoropatellar and femorotibial joints, of the tarsocrural joint. In: McIlwraith C.W. (Ed). Diagnostic and Surgical Arthroscopy of the Horse. second ed. (1990), Lea & Febiger, Philadelphia 85-193
31. McIlwraith C.W. General technique and diagnostic arthroscopy, evaluation of synovial membrane and synovitis. In: McIlwraith C.W. (Ed). Diagnostic and Surgical Arthroscopy of the Horse. second ed. (1990), Lea & Febiger, Philadelphia 27-30
32. Mwale F., Tchetina E.V., Wu C.W., and Poole A.R. The assembly and remodeling of the extracellular matrix in the growth plate in relationship to mineral deposition and cellular hypertrophy: an in situ study of collagens II and IX and proteoglycan. Journal of Bone and Mineral Research 17 (2002) 275-283
33. Nixon A.J. Diagnostic and surgical arthroscopy of the equine shoulder joint. Veterinary Surgery 16 (1987) 44-52
34. Poole A.R. Biochemical/immunochemical biomarkers of osteoarthritis: utility for prediction of incident or progressive osteoarthritis. Rheumatic Disease Clinics of North America 29 (2003) 803-818
35. Reginster J.Y., Deroisy R., Rovati L.C., Lee R.L., Lejeune E., Bruyere O., Giacovelli G., Henrotin Y., Dacre J.E., and Gossett C. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial. The Lancet 357 (2001) 251-256
36. Rosenquist C., Fledelius C., Christgau S., Pedersen B.J., Bonde M., Qvist P., and Christiansen C. Serum CrossLaps one step ELISA. First application of monoclonal antibodies for measurement in serum of bone-related degradation products from C-terminal telopeptides of type I collagen. Clinical Chemistry 44 (1998) 2281-2289
37. Schiller J., Fuchs B., Arnhold J., and Arnold K. Contribution of active oxygen species to cartilage degradation in rheumatic diseases: molecular pathways, diagnosis and potential therapeutic strategies. Current Medicinal Chemistry 10 (2003) 2123-2145
38. Shingleton W.D., Mackie E.J., Cawston T.E., and Jeffcott L.B. Cartilage canals in equine articular/epiphyseal growth cartilage and a possible association with dyschondroplasia. Equine Veterinary Journal 29 (1997) 360-364
39. Stat Soft France, 2003. Statistica (logiciel d'analyse de données) version 6, Paris, France.
40. Stichtenoth D.O., and Frölich J.C. Nitric oxide and inflammatory joint diseases. British Journal of Rheumatology 37 (1998) 246-257
41. Todhunter R.J., and Lust G. Pathophysiology of Synovitis: clinical signs and examination in horses. Compendium on Continuing Education for the Practicing Veterinarian 12 (1990) 980-992
42. Van den Hoogen B.M., Van de Lest C.H.A., Van Weeren P.R., Van Golde L.M.G., and Barneveld A. Changes in proteoglycan metabolism in osteochondrotic articular cartilage of growing foals. Equine Veterinary Journal Supplement 31 (1999) 38-44
43. 2) and neutral metalloproteinases (NMPs) in media of explant cultures of equine synovial membrane and articular cartilage from normal and osteoarthritic joints. Equine Veterinary Journal 32 (2000) 140-150
44. Wu C.W., Tchetina E.V., Mwale F., and Poole A.R. Proteolysis involving matrix metalloproteinase 13 (collagenase-3) is required for chondrocyte differentiation that is associated with matrix mineralization. Journal of Bone and Mineral Research 17 (2002) 639-651