Pharmacokinetics and disposition of memantine in the arterially perfused bovine eye

Pharmaceutical Research

Volumn 23, Issue 12, 2006, Pages 2781-2798

  Koeberle, Martin J ^a   Hughes, Patrick M ^b   Skellern, Graham G ^a   Wilson, Clive G ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b ALLERGAN INC   (United States)

Author keywords

Arterial perfused bovine eye; Melanin binding; Memantine; Ocular drug delivery; Retinal drug delivery

Indexed keywords

MEMANTINE;

ANIMAL TISSUE; ARTERY PERFUSION; ARTICLE; BRUCH MEMBRANE; CELL VIABILITY; CHOROID; CILIARY ARTERY; CILIARY BODY; CONTROLLED STUDY; CORNEA; COW; DRUG DELIVERY SYSTEM; DRUG DISPOSITION; ENZYME ACTIVITY; EXPERIMENTAL MODEL; HISTOPATHOLOGY; INTRAOCULAR PRESSURE; IRIS; NONHUMAN; PRIORITY JOURNAL; RETINA; SCLERA; VITREOUS BODY;

ANIMALS; ARTERIES; BLOOD PRESSURE; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EXCITATORY AMINO ACID ANTAGONISTS; EYE; GLUCOSE; INDICATORS AND REAGENTS; INTRAOCULAR PRESSURE; L-LACTATE DEHYDROGENASE; MASS SPECTROMETRY; MEMANTINE; PERFUSION; REGIONAL BLOOD FLOW; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 33845359786     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-006-9106-2     Document Type: Article

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