Fluorine-18-labelled molecules: Synthesis and application in medical imaging;Les molécules marquées au fluor-18: Synthèse et application en imagerie médicale

Actualite Chimique

Volumn , Issue 301-302, 2006, Pages 93-98

  Dollé, Frédéric ^a   Perrio, Cécile ^b   Barré, Louisa ^c,e   Lasne, Marie Claire ^b   Bars, Didier Le ^d  

^a DIF   (France)

^b CNRS   (France)

^c Umr CEA 2E Groupe de Développements   (France)

^d UNIVERSITÉ LYON 1   (France)

^e GIP CYCERON   (France)

Author keywords

Fluorine 18; Medical imaging; Positron; Radiosynthesis; Radiotracer; Tomography

Indexed keywords

EID: 33845356109     PISSN: 01519093     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (28)

1. +-emitting compounds based on fluorine-18, Topics in Current Chemistry, W. Krause (ed.), Springer-Verlag, Berlin-Heidelberg, 2002, 222, p. 201.
2. Welch M.J., Redvanly C.S., Handbook of Radiopharmaceuticals. Radiochemistry and Applications, M.J. Welch, C.S. Redvanly (eds), Wiley Interscience, 2003, p. 1.
3. Okarvi S.M., Recent progress in fluorine-18 labelled peptide radiopharmaceuticals, Eur. J. Nucl. Med., 2001, 28, p. 929.
4. Wilbur D.S., Radiohalogenation of proteins: an overview of radionuclides, labeling methods and reagents for conjugate labelling, Bioconj. Chem., 1992, 3, p. 433.
5. 18F]fluoro-pyridin-3-yloxy)-propyl]-acetamide, Bioconj. Chem., 2004, 15, p. 617.
6. 18F]Fluoro-L-DOPA by radiofluorodestannylation: a short and simple synthesis of a new labelling precursor, J. Labelled Comp. Radiopharm., 1998, 41, p. 105.
7. 18F]fluoro-L-DOPA preparation: precursor synthesis, preparative HPLC purification and determination of radiochemical purity, Nucl. Med. Biol., 2002, 29, p. 477.
8. 18F]fluoro-2-deoxy-D-glucose using aminopolyether supported nucleophilic substitution, J. Nucl. Med., 1986, 27, p. 235.
9. 18F]FDG without an evaporation step using ionic liquid, Appl. Radiat. Isot., 2004, 61, p. 1241.
10. 18F]FDG module, Nucl. Med. Biol., 2005, 32, p. 899.
11. 18F]fluorothymidlne, Nucl. Med. Biol., 2004, 31, p. 803.
12. 18F]fluorothymidine using three precursors, Appl. Radiat. Isot., 2006, 64, p. 187.
13. 18F]MPPF, a fluoro analog of WAY-100635, Nucl. Med. Biol., 1998, 25, p. 343.
14. 2 receptor, Bioorg. Med. Chem., 2000, 8, p. 2511.
15. 3 receptor partial agonist, Bioorg. Med. Chem., 1998, 6, p. 789.
16. Dollé F., Fluorine-18-labelled fluoropyridines: advances In radiopharmaceutical design, Curr. Pharm. Design, 2005, 11, p. 3221.
17. Dollé F., Dolci L., Valette H., Hinnen F., Vaufrey F., Guenther I., Fuseau C., Coulon C., Bottlaender M., Crouzel C., Synthesis and nicotinic acetyicholine receptor in vivo binding properties of 2-fluoro-3-[2(S)-2- azetidinylmethoxy]pyridine: a new positron emission tomography ligand for nicotinic receptors, J. Med. Chem., 1999, 42, p. 2251.
18. Tavitian B., Terrazzino S., Kühnast B., Marzabal S., Stettler O., Dollé F., Deverre J.-R., Jobert A., Hinnen F., Bendriem B., Crouzel C., DiGiamberardino L., In vivo imaging of oligonucleotides with positron emission tomography, Nature Medicine, 1998, 4, p. 2467.
19. Tavitian B., In vivo imaging with oligonucleotides for diagnosis and drug development, Gut., 2003, 52, p. 40.
20. Tavitian B., Oligonucleotides as radiopharmaceuticals. Molecular Imaging, E. Schering Research Foundation Workshop, Springer Verlag, Berlin-Heidelberg- New York, 2004, 49, p. 1.
21. Wester H.J., Harnacher K., Stöcklin G., A comparative study of N.C.A, fluorine-18 labeling of proteins via acylation and photoactivation, Nucl. Med. Biol., 1996, 23, p. 365.
22. 18F]fluoropyridine-based maleimide reagent for the labeling of peptides and proteins, Bioconj. Chem., 2005, 16, p. 406.
23. 18F]-labeled maleimides, their use for marking macromolecules for medical imaging, PCT Int. Appl., 2004, WO 2004002984.
24. 18F]fluoromethyl-L-tyrosine as tumor Imaging tracers by PET, Nucl. Med. Biol., 2004, 31, p. 191.
25. 18F-labeled choline as an oncologic tracer for positron emission tomography: initial findings in prostate cancer, Cancer Research, 2000, 61, p. 110.
26. Gillies J.M., Prenant C., Chimon G.N., Smethurst G.J., Perrie W., Hambletta I., Dekker B., Zweit J., Microfluidic reactor for the radiosynthesis of PET radiotracers, Appl. Rad. Isot., 2006, 84, p. 325.
27. Lee C.C., Sui G., Elizarov A., Shu C.J., Shin Y.S., Dooley A.N., Huang J., Daridon A., Wyatt P., Stout D., Kolb H.C., Witte O.N., Satyamurthy N., Heath J.R., Phelps M.E., Quake S.R., Tseng H.R., Multistep synthesis of a radiolabeled imaging probe using integrated microfluidics, Science, 2005, 310, p. 1793.
28. Bergman J., Solin O., Fluorine-18-labeled fluorine gas for synthesis of tracer molecules, Nucl. Med. Biol., 1997, 24, p, 677.