Lack of trigeminal nerve toxicity in rats exposed to trichloroethylene vapor for 13 weeks

International Journal of Toxicology

Volumn 25, Issue 6, 2006, Pages 531-540

  Albee, Ralph R ^a   Spencer, Pamela J ^a   Johnson, Keith A ^a   Bradley, Greg J ^a   Marable, Brian R ^a,d   Wilmer, Jan W ^b   Mattsson, Joel L ^c  

^a DOW CHEMICAL COMPANY   (United States)

^b DOW EUROPE GMBH   (Switzerland)

^c DOW AGROSCIENCES LLC   (United States)

^d SYNGENTA CROP PROTECTION   (United States)

Author keywords

1,1,2 Trichloroethylene; Evoked Potential; Neuropathology; Ototoxicity; Rat; Subchronic Exposure; TCE

Indexed keywords

TRICHLOROETHYLENE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ELECTRODIAGNOSIS; EVOKED BRAIN STEM AUDITORY RESPONSE; FEMALE; GRIP STRENGTH; HAIR CELL; HISTOPATHOLOGY; MALE; NERVE POTENTIAL; NEUROPATHOLOGY; NEUROTOXICITY; NONHUMAN; OTOTOXICITY; RAT; TRIGEMINAL NERVE; VAPOR;

ADMINISTRATION, INHALATION; ANIMALS; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; EVOKED POTENTIALS, SOMATOSENSORY; FEMALE; MALE; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORGAN OF CORTI; RATS; RATS, INBRED F344; SOLVENTS; TRICHLOROETHYLENE; TRIGEMINAL NERVE;

EID: 33845354053     PISSN: 10915818     EISSN: 1092874X     Source Type: Journal    
DOI: 10.1080/10915810600972678     Document Type: Article

References (39)

1. Adams, E. M., H. C. Spencer, V. K. Rowe, D. D. McCollister, and D. D. Irish. 1951. Vapor toxicity of trichloroethylene determined by experiments on laboratory animals. Arch. Ind. Hyg. Occ. Med. 4:469-481.
2. Albee, R. R., K. D. Nitschke, J. L. Mattsson, and K. E. Stebbins. 1997. Dichloroacetylene: Effects on the rat trigeminal nerve somatosensory evoked potential. Neurotoxicol. Teratol. 19:27-37.
3. Anger, W. K., and B. J. Johnson. 1985. Chemicals affecting behavior. In Neurotoxicity of industrial and commercial products, ed. J. L. O'Donoghue, Vol. 1, 68-69. Florida: CRC Press.
4. Annau, Z. 1981. The neurobehavioral toxicity of trichloroethylene. Neurobehav. Toxicol. Teratol. 3:417-424.
5. ATSDR, 1996. Agency for Toxic Substances and Disease Registry. United States Department of Health and Human Services. Toxicological profile for trichloroethylene (update). Washington DC: U.S. Government Printing Office.
6. Barret, L., P. Arsac, M. Vincent, J. Faure, S. Garrel, and F. Reymond. 1982. Evoked trigeminal nerve potential in chronic trichloroethylene intoxication. J. Toxicol. Clin. Toxicol. 19:419-23.
7. Barret, L., S. Garrel, V. Danel, and J. L. Debru. 1987. Chronic trichloroethylene intoxication: A new approach by trigeminal-evoked potentials? Arch. Environ. Health 42:297-302.
8. Bruning, J. K., and B. L. Kintz. 1977. Computational handbook of statistics, Glenview, IL: Scott, Foresman and Company.
9. Crofton, K. M., T. L. Lassiter, and C. S. Rebert. 1994. Solvent-induced ototoxicity in rats: An atypical selective mid-frequency hearing deficit. Hear. Res. 80:25-30.
10. Crofton, K. M., and X. Zhao. 1993. Mid-frequency hearing loss in rats following inhalation exposure to trichloroethylene: Evidence from reflex modification audiometry. Neurotoxicol. Teratol. 15:413-23.
11. Edwards, P. M., and V. H. Parker. 1977. A simple, sensitive, and objective method for early assessment of acrylamide neuropathy in rats. Toxicol. Appl. Pharmacol. 40:589-591.
12. Eisenbrandt, D. L., J. L. Mattsson, R. R. Albee, P. J. Spencer, and K. A. Johnson. 1990. Spontaneous lesions in subchronic neurotoxicity testing of rats. Toxicol. Pathol. 18:154-164.
13. Fechter, L. D., Y. Liu, D. W. Herr, and K. M. Crofton. 1998. Trichloroethylene ototoxicity: Evidence for a cochlear origin. Toxicol. Sci. 42:28-35.
14. Feldman, R. G., J. Chirico-Post, and S. P. Proctor. 1988. Blink reflex latency after exposure to trichloroethylene in well water. Arch. Environ. Health 43:143-148.
15. Feldman, R. G., C. Niles, S. P. Proctor, and J. Jabre. 1992. Blink reflex measurement of effects of trichloroethylene exposure on the trigeminal nerve. Muscle Nerve 15:490-495.
16. Halogenated Solvents Industry Alliance. 1996. White paper on trichloroethylene. Washington, D.C.
17. Hartman, D. E. 1988. Neuropsychological toxicology: Identification and assessment of human neurotoxic syndromes. New York: Pergamon Press.
18. IARC. 1986. Monograph on the evaluation of the carcinogenic risk of dichloroacetylene. IARC Monogr. 39:369-379.
19. Jaspers, R. M., H. Muijser, J. H. Lammers, and B. M. Kulig. 1993. Mid-frequency hearing loss and reduction of acoustic startle responding in rats following trichloroethylene exposure. Neurotoxicol. Teratol. 15:407-412.
20. Kjellstrand, P., M. Kanje, L. Mansson, M. Bjerkemo, I. Mortensen, J. Lanke, and B. Holmquist. 1981. Trichloroethylene: Effects on body and organ weights in mice, rats and gerbils. Toxicology 21:105-115.
21. Kulig, B. M. 1987. The effects of chronic trichloroethylene exposure on neurobehavioral functioning in the rat. Neurotoxicol. Teratol. 9:171-178.
22. Lash, L. H., J. W. Fisher, J. C. Lipscomb, and J. C. Parker. 2000. Metabolism of trichloroethylene. Environ. Health Perspect. 108(Suppl. 2):177-200.
23. Mantel, N. 1980. Assessing laboratory evidence for neoplastic activity. Biometrics 36:381-399.
24. Mattsson, J. L., and R. R. Albee. 1988. Sensory evoked potentials in neurotoxicology. Neurotoxicol. Teratol. 10:435-443.
25. Mattsson, J. L., R. R. Albee, and D. L. Eisenbrandt. 1990. Neurotoxicologic evaluation of rats after 13 weeks of inhalation exposure to dichloromethane or carbon monoxide. Pharmacol. Biochem. Behav. 36:671-681.
26. Mattsson, J. L., R. R. Albee, L. G. Lomax , M. J. Beekman, and P. J. Spencer. 1993. Neurotoxicologic examination of rats exposed to 1,1,1-trichloroethane vapor for 13 weeks. Neurotoxicol. Teratol. 15:313-326.
27. Mattsson, J. L., R. R. Albee, B. L. Yano, G. Bradley, and P. J. Spencer. 1998. Neurotoxicologic examination of rats exposed to 1,1,2,2- tetrachloroethylene (perchloroethylene) vapor for 13 weeks. Neurotoxicol. Teratol. 20:83-98.
28. Mattsson, J. L., K. A. Johnson, and R. R. Albee. 1986. Lack of neuropathologic consequences of repeated dermal exposure to 2,4- dichlorophenoxyacetic acid in rats. Fundam. Appl. Toxicol. 6:175-181.
29. Miller, R. R., R. L. Letts, W. J. Potts, and M. J. McKenna. 1980. Improved methodology for generating controlled test atmospheres. Am. Ind. Hyg. Assoc. J. 41:844-846.
30. National Research Council. 2006. Assessing the human health risks of trichloroethylene: key scientific issues. Washington DC: Committee on Human Health Risks of Trichloroethylene, NRC (nttp://www.nap.edu/catalog/11707.html).
31. New York State Department of Health. 2005. Trichloroethene Air Criteria Document. Draft Report. Troy, NY: NYSDOH, Center for Environmental Health. August, 2005.
32. Rebert, C. S. 1983. Multisensory evoked potentials in experimental and applied neurotoxicology. Neurobehav. Toxicol. Teratol. 5:659-671.
33. Rebert, C. S, V. L. Day, M. J. Matteucci, and G. T. Pryor. 1991. Sensory-evoked potentials in rats chronically exposed to trichloroethylene: Predominant auditory dysfunction. Neurotoxicol. Teratol. 13:83-90.
34. Rogan, J. C., and H. J. Keselman. 1977. Is the ANOVA F-test robust to variance heterogeneity when sample sizes are equal?: An investigation via a coefficient of variation. Am. Educat. Res. J. 14:493-498.
35. Spencer, P. S., and H. H. Schaumburg. 1985. Organic solvent neurotoxicity. Facts and research needs. Scand. J. Work Environ. Health 11(Suppl. 1):53-60.
36. Sullivan, M. J. and R. B. Conolly. 1988. Dose-response hearing loss for white noise in the Sprague-Dawley rat. Fundam. Appl. Toxicol. 10:109-113.
37. Sullivan, J. J., K. E. Rarey and R. B. Conolly. 1989. Ototoxicity of toluene in rats. Neurotoxicol. Teratol. 10:525-530.
38. Tukey, J. W., J. L. Ciminera, and J. F. Heyse. 1985. Testing the statistical certainty of a response to increasing doses of a drug. Biometrics 41:295-301.
39. USEPA 1991. Pesticide assessment guidelines, subdivision F, hazard evaluation: Human and domestic animals, addendum 10, neurotoxicity series 81, 82, and 83. Health Effects Division, Office of Pesticides Programs. Publication PB 91-154617.