Differential induction of Th1-prone immunity by human dendritic cells activated with Sporothrix schenckii of cutaneous and visceral origins to determine their different virulence

International Immunology

Volumn 18, Issue 12, 2006, Pages 1637-1646

  Uenotsuchi, Takeshi ^a   Takeuchi, Satoshi ^a   Matsuda, Tetsuo ^a   Urabe, Kazunori ^a   Koga, Tetsuya ^a   Uchi, Hiroshi ^a   Nakahara, Takeshi ^a   Fukagawa, Shuji ^a   Kawasaki, Masako ^b   Kajiwara, Hideko ^c   Yoshida, Shin Ichi ^c   Moroi, Yoichi ^a   Furue, Masutaka ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KANAZAWA MEDICAL UNIVERSITY   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE MARKER; CORTICOSTEROID; CYTOKINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE;

ARTICLE; CELL ACTIVATION; CELL STIMULATION; CELLULAR IMMUNITY; CLINICAL FEATURE; CONIDIUM; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; DENDRITIC CELL; DERMATOMYCOSIS; ENZYME PHOSPHORYLATION; FUNGAL STRAIN; FUNGAL VIRULENCE; FUNGUS ISOLATION; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNE STATUS; INTESTINE INFECTION; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPOROTHRIX SCHENCKII; SPOROTRICHOSIS; STRAIN DIFFERENCE; TH1 CELL; CELL DIFFERENTIATION; CLASSIFICATION; CYTOLOGY; IMMUNOLOGY; ISOLATION AND PURIFICATION; LYMPHOCYTE ACTIVATION; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; SPOROTHRIX; VIRULENCE;

CELL DIFFERENTIATION; DENDRITIC CELLS; DERMATOMYCOSES; HUMANS; LYMPHOCYTE ACTIVATION; MONOCYTES; SPOROTHRIX; SPOROTRICHOSIS; TH1 CELLS; VIRULENCE;

EID: 33845352186     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxl097     Document Type: Article

References (37)

1. Travassos, L. R. 1985. Sporothrix schenckii. In Szaniszlo, P. J., ed., Fungal Dimorphism with Emphasis on Fungi Pathogenic for Humans, p. 121. Plenum Press, New York.
2. Carvalho, M. T. T., de Castro, A. P., Baby, C., Werner, B., Neto, J. F. and Queiroz-Telles, F. 2002. Disseminated cutaneous sporotrichosis in a patient with AIDS: Report of a case. Rev. Soc. Bras. Med. Trop. 35:655.
3. Ware, A. J., Cockerell, C. J., Skiest, D. J. and Kussman, H. M. 1999. Disseminated sporotrichosis with extensive cutaneous involvement in a patient with AIDS. J. Am. Acad. Dermatol. 40: 350.
4. Hay, R. J. and Moore, M. 1998. Sporotrichosis. In Champion, R. H., Burton, J. L., Burns, D. A. and Breathnach, S. M., eds, Rook/ Wilkinson/ Ebling Textbook of Dermatology, 6th edn. p. 1351. Blackwell Science, UK.
5. Weedon, D. 1997. Sporotrichosis. In Weedon, D., ed., Skin Pathology, p. 569. Churchill Livingstone, New York.
6. Bonifaz, A., Peniche, A., Mercadillo, P. and Saul, A. 2001. Successful treatment of AIDS-related disseminated cutaneous sporotrichosis with itraconazole. AIDS Patient Care STDS 15:603.
7. Carlos, I. Z., Sgarbi, D. B., Angluster, J., Alviano, C. S. and Silva, C. L. 1992. Detection of cellular immunity with the soluble antigen of the fungus Sporothrix schenckii in the systemic form of the disease. Mycopathologia 117:139.
8. Tachibana, T., Matsuyama, T. and Mitsuyama, M. 1999. Involvement of CD4+ T cells and macrophages in acquired protection against infection with Sporothrix schenckii in mice. Med. Mycol. 37:397.
9. Koga, T., Duan, H. and Furue, M. 2002. Immunohistochemical detection of interferon-γ-producing cells in granuloma formation of sporotrichosis. Med. Mycol. 40:111.
10. Fujimura, T., Asai, T., Muguruma, K., Masuzawa, M. and Katsuoka, K. 1996. Local expression of migration inhibitory factor and Th1 type cytokine mRNA in sporotrichosis lesions. Acta Dermato-Venereol. (Stockh.) 76:321.
11. Nakahara, T., Uchi, H., Urabe, K., Chen, Q., Furue, M. and Moroi, Y. 2004. Role of c-Jun N-terminal kinase on lipopolysaccharide induced maturation of human monocyte-derived dendritic cells. Int. Immunol. 16:1701.
12. Koga, T., Duan, H., Urabe, K. and Furue, M. 2001. Immunohistochemical localization of activated and mature CD83+ dendritic cells in granulomas of sporotrichosis. Eur. J. Dermatol. 11:527.
13. Romani, N., Reider, D., Heuer, M. et al. 1996. Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability. J. Immunol. Methods 196:137.
14. Kiertscher, S. M. and Roth, M. D. 1996. Human CD14+ leukocytes acquire the phenotype and function of antigen-presenting dendritic cells when cultured in GM-CSF and IL-4. J. Leukoc. Biol. 59:208.
15. Liu, Y. J. 2001. Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity. Cell 106:259.
16. Rutz, S., Mordmuller, B., Sakano, S. and Scheffold, A. 2005. Notch ligands Delta-like 1, Delta-like 4 and Jagged 1 differentially regulate activation of peripheral T helper cells. Eur. J. Immunol. 35:2443.
17. Amsen, D., Blander, J. M., Lee, G. R., Tanigaki, K., Honjo, T. and Flavell, R. A. 2004. Instruction of distinct CD4 T helper cell fates by different Notch ligands on antigen-presenting cells. Cell 117:515.
18. Morris-Jones, R. 2002. Sporotrichosis. Clin. Exp. Dermatol. 27:427.
19. Lilic, D. 2002. New perspectives on the immunology of chronic mucocutaneous candidiasis. Curr. Opin. Infect. Dis. 15:143.
20. Romani, L., Francesco, B. and Puccetti, P. 2002. Fungi, dendritic cells and receptors: A host perspective of fungal virulence. Trends Microbiol. 10:508.
21. Kim, M. Y., Bekiaris, V., McConnel, F. M., Gaspal, F. M. C., Raykundalia, C. and Lane, P. J. L. 2005. OX40 signals during priming on dendritic cells inhibit CD4 T cell proliferation: IL-4 switches off OX40 signals enabling rapid proliferation of Th2 effectors. J. Immunol. 174:1433.
22. Kwon-Chung, K. J. 1979. Comparison of isolates of Sporothrix schenckii obtained from fixed cutaneous lesions with isolates from other types of lesions. J. Infect. Dis. 139:424.
23. de Albornoz, M. B., Mendoza, M. and Torres, E. D. 1986. Growth temperatures of isolates of Sporothrix schenckii from disseminated and fixed cutaneous lesions of sporotrichosis. Mycopathologia. 95:81.
24. Bustamante, B. and Campos, P. E. 2001. Endemic sporotrichosis. Curr. Opin. Infect. Dis. 14:145.
25. Tachibana, T., Matsuyama, T., Ito, M. and Mitsuyama, M. 2001. Sporothrix schenckii thermo-intolerant mutants losing fatal visceral infectivity but retaining high cutaneous infectivity. Med. Mycol. 39:295.
26. Locksley, R. M., Heinzel, F. P., Fankhauser, J. E., Nelson, C. S. and Sadick, M. D. 1988. Cutaneous host defense in Leishmaniasis: Interaction of isolated dermal macrophages and epidermal Langerhans cells with the insect-stage promastigote. Infect. Immun. 56:336.
27. von Stebut, E., Belkaid, Y., Jakob, T., Sacks, D. L. and Udey, M. C. 1998. Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implication for the initiation of anti-Leishmania immunity. J. Exp. Med. 188:1547.
28. Buentke, E. and Scheynius, A. 2003. Dendritic cells and fungi. Acta Pathol. Microbiol. Immunol. Scand. 111:789.
29. Netea, M. G., Van der Graaf, C., Van der Meer, J. W. M. and Kullberg, B. J. 2004. Recognition of fungal pathogens by Toll-like receptors. Eur. J. Clin. Microbiol. Infect. Dis. 23:672.
30. Brown, G. D. 2006. Dectin-1: A signaling non-TLR pattern-recognition receptor. Nat. Rev. Immunol. 6:33.
31. Shoham, S. and Lavitz, S. M., The immune response to fungal infections. Br. J. Haematol. 129:569.
32. Takeda, K. and Akira, S. 2004. TLR signaling pathways. Semin. Immunol. 16:3.
33. Roeder, A., Kirschning, C. J., Rupoc, R. A., Schaller, M., Weindl, G. and Korting, H. C. 2004. Toll-like receptors as key mediators in innate antifungal immunity. Med. Mycol. 42:485.
34. Kisho, T. and Akira, S. 2006. Toll-like receptor function and signaling. J. Allergy Clin. Immunol. 117:979.
35. Netea, M. G., Van der Meer, J. W. M. and Kullberg, B. J. 2006. Role of the dual interaction of fungal pathogens with pattern recognition receptors in the activation and modulation of host defence. Clin. Microbiol. Infect. 12:404.
36. Lopes-Bezerra, L. M., Shubach, A. and Costa, R. O. 2006. Sporothrix schenckii and sporotrichosis. An. Acad. Bras. Cienc. 78:293.
37. Fernandes, K. S. S., Mathews, H. L. and Lopes-Bezerra, L. M. 1999. Differences in virulence of Sporothrix schenckii conidia related to culture conditions and cell-wall composition. J. Med. Microbiol. 48:195.