-
1
-
-
4043181214
-
Cancer genes and the pathways they control
-
Vogelstein B, Kinzler KW. Cancer genes and the pathways they control. Nat Med 2004; 10:789-799.
-
(2004)
Nat Med
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
2
-
-
33746118320
-
Trastuzumab and breast cancer: Developments and current status
-
Tokunaga E, Oki E, Nishida K, et al. Trastuzumab and breast cancer: developments and current status. Int J Clin Oncol 2006; 11:199-208.
-
(2006)
Int J Clin Oncol
, vol.11
, pp. 199-208
-
-
Tokunaga, E.1
Oki, E.2
Nishida, K.3
-
3
-
-
17044433023
-
Mutation detection, interpretation, and applications in the clinical laboratory setting
-
Strom CM. Mutation detection, interpretation, and applications in the clinical laboratory setting. Mutat Res 2005; 573 (1-2):160-167. This review highlights the role of quantitative assays in diagnostic testing.
-
(2005)
Mutat Res
, vol.573
, Issue.1-2
, pp. 160-167
-
-
Strom, C.M.1
-
4
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
[Epub ahead of print]
-
Sjoblom T, Jones S, Wood LD, et al. The consensus coding sequences of human breast and colorectal cancers. Science 2006 [Epub ahead of print].
-
(2006)
Science
-
-
Sjoblom, T.1
Jones, S.2
Wood, L.D.3
-
5
-
-
0035001201
-
Emerging homogeneous DNA-based technologies in the clinical laboratory
-
Foy CA, Parkes HC. Emerging homogeneous DNA-based technologies in the clinical laboratory. Clin Chem 2001; 47:990-1000.
-
(2001)
Clin Chem
, vol.47
, pp. 990-1000
-
-
Foy, C.A.1
Parkes, H.C.2
-
7
-
-
2342630688
-
PCR-based detection of minority point mutations
-
Mike Makrigiorgos G. PCR-based detection of minority point mutations. Hum Mutat 2004; 23:406-412.
-
(2004)
Hum Mutat
, vol.23
, pp. 406-412
-
-
Mike Makrigiorgos, G.1
-
8
-
-
23844497341
-
Sensitive sequencing method for KRAS mutation detection by pyrosequencing
-
Ogino S, Kawasaki T, Brahmandam M, et al. Sensitive sequencing method for KRAS mutation detection by pyrosequencing. J Mol Diagn 2005; 7:413-421.
-
(2005)
J Mol Diagn
, vol.7
, pp. 413-421
-
-
Ogino, S.1
Kawasaki, T.2
Brahmandam, M.3
-
9
-
-
32944468710
-
A rapid and sensitive enzymatic method for epidermal growth factor receptor mutation screening
-
Janne PA, Borras AM, Kuang Y, et al. A rapid and sensitive enzymatic method for epidermal growth factor receptor mutation screening. Clin Cancer Res 2006; 12 (3 Pt 1):751-758.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.3 PART 1
, pp. 751-758
-
-
Janne, P.A.1
Borras, A.M.2
Kuang, Y.3
-
10
-
-
13844304889
-
LigAmp for sensitive detection of single-nucleotide differences
-
Shi C, Eshleman SH, Jones D, et al. LigAmp for sensitive detection of single-nucleotide differences. Nat Methods 2004; 1:141-147.
-
(2004)
Nat Methods
, vol.1
, pp. 141-147
-
-
Shi, C.1
Eshleman, S.H.2
Jones, D.3
-
11
-
-
33746100318
-
Detection of epidermal growth factor receptor mutations in serum as a predictor of the response to gefitinib in patients with nonsmall-cell lung cancer
-
Kimura H, Kasahara K, Kawaishi M, et al. Detection of epidermal growth factor receptor mutations in serum as a predictor of the response to gefitinib in patients with nonsmall-cell lung cancer. Clin Cancer Res 2006; 12:3915-3921. Report on a blood-based assay to detect EGFR mutations in lung cancer. They used a Scorpion Amplified Refractory Mutation System for mutation detection.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3915-3921
-
-
Kimura, H.1
Kasahara, K.2
Kawaishi, M.3
-
12
-
-
0347762809
-
Principle and applications of digital PCR
-
Pohl G, Shih Ie M. Principle and applications of digital PCR. Expert Rev Mol Diagn 2004; 4:41-47.
-
(2004)
Expert Rev Mol Diagn
, vol.4
, pp. 41-47
-
-
Pohl, G.1
Shih Ie, M.2
-
13
-
-
25144461054
-
Single-molecule PCR: An artifact-free PCR approach for the analysis of somatic mutations
-
Kraytsberg Y, Khrapko K. Single-molecule PCR: an artifact-free PCR approach for the analysis of somatic mutations. Expert Rev Mol Diagn 2005; 5:809-815. Recent review about digital PCR approaches for the analysis of somatic mutations.
-
(2005)
Expert Rev Mol Diagn
, vol.5
, pp. 809-815
-
-
Kraytsberg, Y.1
Khrapko, K.2
-
14
-
-
0031243268
-
Single-molecule detection of specific nucleic acid sequences in unamplified genomic DNA
-
Castro A, Williams JG. Single-molecule detection of specific nucleic acid sequences in unamplified genomic DNA. Anal Chem 1997; 69:3915-3920.
-
(1997)
Anal Chem
, vol.69
, pp. 3915-3920
-
-
Castro, A.1
Williams, J.G.2
-
15
-
-
28044468634
-
Detection and quantification of mutations in the plasma of patients with colorectal tumors
-
Diehl F, Li M, Dressman D, et al. Detection and quantification of mutations in the plasma of patients with colorectal tumors. Proc Natl Acad Sci USA 2005; 102:16368-16373. Application of BEAMing for the quantification of mutant DNA in plasma from cancer patients.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 16368-16373
-
-
Diehl, F.1
Li, M.2
Dressman, D.3
-
16
-
-
0031831323
-
Mutation detection and single-molecule counting using isothermal rolling-circle amplification
-
Lizardi PM, Huang X, Zhu Z, et al. Mutation detection and single-molecule counting using isothermal rolling-circle amplification. Nat Genet 1998; 19:225-232.
-
(1998)
Nat Genet
, vol.19
, pp. 225-232
-
-
Lizardi, P.M.1
Huang, X.2
Zhu, Z.3
-
17
-
-
27144529891
-
Scoring single-nucleotide polymorphisms at the single-molecule level by counting individual DNA cleavage events on surfaces
-
Nie B, Shortreed MR, Smith LM. Scoring single-nucleotide polymorphisms at the single-molecule level by counting individual DNA cleavage events on surfaces. Anal Chem 2005; 77:6594-6600.
-
(2005)
Anal Chem
, vol.77
, pp. 6594-6600
-
-
Nie, B.1
Shortreed, M.R.2
Smith, L.M.3
-
18
-
-
33747781419
-
Digital quantification using amplified single-molecule detection
-
Jarvius J, Melin J, Goransson J, et al. Digital quantification using amplified single-molecule detection. Nat Methods 2006; 3:725-727. First report describing the counting of RCA products in solution.
-
(2006)
Nat Methods
, vol.3
, pp. 725-727
-
-
Jarvius, J.1
Melin, J.2
Goransson, J.3
-
19
-
-
18744416025
-
Quantification of random genomic mutations
-
Bielas JH, Loeb LA. Quantification of random genomic mutations. Nat Methods 2005; 2:285-290. Sensitive assay for measuring the background mutation rate in human cells.
-
(2005)
Nat Methods
, vol.2
, pp. 285-290
-
-
Bielas, J.H.1
Loeb, L.A.2
-
20
-
-
0033548686
-
Fluorescence spectroscopy of single biomolecules
-
Weiss S. Fluorescence spectroscopy of single biomolecules. Science 1999; 283:1676-1683.
-
(1999)
Science
, vol.283
, pp. 1676-1683
-
-
Weiss, S.1
-
21
-
-
31344472963
-
Single-molecule detection and probe strategies for rapid and ultrasensitive genomic detection
-
Yeh HC, Chao SY, Ho YP, et al. Single-molecule detection and probe strategies for rapid and ultrasensitive genomic detection. Curr Pharm Biotechnol 2005; 6:453-461. Review of state-of-the-art single-molecule detection methods.
-
(2005)
Curr Pharm Biotechnol
, vol.6
, pp. 453-461
-
-
Yeh, H.C.1
Chao, S.Y.2
Ho, Y.P.3
-
22
-
-
0038581841
-
Approaching real-time molecular diagnostics: Single-pair fluorescence resonance energy transfer (spFRET) detection for the analysis of low abundant point mutations in K-ras oncogenes
-
Wabuyele MB, Farquar H, Stryjewski W, et al. Approaching real-time molecular diagnostics: single-pair fluorescence resonance energy transfer (spFRET) detection for the analysis of low abundant point mutations in K-ras oncogenes. J Am Chem Soc 2003; 125:6937-6945.
-
(2003)
J Am Chem Soc
, vol.125
, pp. 6937-6945
-
-
Wabuyele, M.B.1
Farquar, H.2
Stryjewski, W.3
-
23
-
-
33644784882
-
Quantitative detection of individual cleaved DNA molecules on surfaces using gold nanoparticles and scanning electron microscope imaging
-
Nie B, Shortreed MR, Smith LM. Quantitative detection of individual cleaved DNA molecules on surfaces using gold nanoparticles and scanning electron microscope imaging. Anal Chem 2006; 78:1528-1534. Method for counting of mutant DNA molecules bound to a solid support.
-
(2006)
Anal Chem
, vol.78
, pp. 1528-1534
-
-
Nie, B.1
Shortreed, M.R.2
Smith, L.M.3
-
24
-
-
1942499454
-
Advanced sequencing technologies: Methods and goals
-
Shendure J, Mitra RD, Varma C, et al. Advanced sequencing technologies: methods and goals. Nat Rev Genet 2004; 5:335-344.
-
(2004)
Nat Rev Genet
, vol.5
, pp. 335-344
-
-
Shendure, J.1
Mitra, R.D.2
Varma, C.3
-
25
-
-
21444456797
-
Toward the 1,000 dollars human genome
-
Bennett ST, Barnes C, Cox A, et al. Toward the 1,000 dollars human genome. Pharmacogenomics 2005; 6:373-382.
-
(2005)
Pharmacogenomics
, vol.6
, pp. 373-382
-
-
Bennett, S.T.1
Barnes, C.2
Cox, A.3
-
26
-
-
28844463698
-
Emerging technologies in DNA sequencing
-
Metzker ML. Emerging technologies in DNA sequencing. Genome Res 2005; 15:1767-1776.
-
(2005)
Genome Res
, vol.15
, pp. 1767-1776
-
-
Metzker, M.L.1
-
27
-
-
0037388048
-
Sequence information can be obtained from single DNA molecules
-
Braslavsky I, Hebert B, Kartalov E, et al. Sequence information can be obtained from single DNA molecules. Proc Natl Acad Sci USA 2003; 100:3960-3964.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3960-3964
-
-
Braslavsky, I.1
Hebert, B.2
Kartalov, E.3
-
28
-
-
0024245669
-
Amplification of human minisatellites by the polymerase chain reaction: Towards DNA fingerprinting of single cells
-
Jeffreys AJ, Wilson V, Neumann R, et al. Amplification of human minisatellites by the polymerase chain reaction: towards DNA fingerprinting of single cells. Nucleic Acids Res 1988; 16:10953-10971.
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 10953-10971
-
-
Jeffreys, A.J.1
Wilson, V.2
Neumann, R.3
-
30
-
-
0035815919
-
Detecting colorectal cancer in stool with the use of multiple genetic targets
-
Dong SM, Traverso G, Johnson C, et al. Detecting colorectal cancer in stool with the use of multiple genetic targets. J Natl Cancer Inst 2001; 93:858-865.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 858-865
-
-
Dong, S.M.1
Traverso, G.2
Johnson, C.3
-
31
-
-
0037454224
-
Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma
-
Singer G, Oldt R 3rd, Cohen Y, et al. Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma. J Natl Cancer Inst 2003; 95:484-486.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 484-486
-
-
Singer, G.1
Oldt III, R.2
Cohen, Y.3
-
32
-
-
0034940317
-
Molecular genetic analysis of appendiceal mucinous adenomas in identical twins, including one with pseudomyxoma peritonei
-
Shih IM, Yan H, Speyrer D, et al. Molecular genetic analysis of appendiceal mucinous adenomas in identical twins, including one with pseudomyxoma peritonei. Am J Surg Pathol 2001; 25:1095-1099.
-
(2001)
Am J Surg Pathol
, vol.25
, pp. 1095-1099
-
-
Shih, I.M.1
Yan, H.2
Speyrer, D.3
-
33
-
-
0037204202
-
Detection of APC mutations in fecal DNA from patients with colorectal tumors
-
Traverso G, Shuber A, Levin B, et al. Detection of APC mutations in fecal DNA from patients with colorectal tumors. N Engl J Med 2002; 346:311-320.
-
(2002)
N Engl J Med
, vol.346
, pp. 311-320
-
-
Traverso, G.1
Shuber, A.2
Levin, B.3
-
35
-
-
0033573165
-
In situ localized amplification and contact replication of many individual DNA molecules
-
Mitra RD, Church GM. In situ localized amplification and contact replication of many individual DNA molecules. Nucleic Acids Res 1999; 27:e34.
-
(1999)
Nucleic Acids Res
, vol.27
-
-
Mitra, R.D.1
Church, G.M.2
-
36
-
-
0042307371
-
Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations
-
Dressman D, Yan H, Traverso G, et al. Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations. Proc Natl Acad Sci USA 2003; 100:8817-8822.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8817-8822
-
-
Dressman, D.1
Yan, H.2
Traverso, G.3
-
37
-
-
0348251333
-
A massively parallel PicoTiterPlate based platform for discrete picoliter-scale polymerase chain reactions
-
Leamon JH, Lee WL, Tartaro KR, et al. A massively parallel PicoTiterPlate based platform for discrete picoliter-scale polymerase chain reactions. Electrophoresis 2003; 24:3769-3777.
-
(2003)
Electrophoresis
, vol.24
, pp. 3769-3777
-
-
Leamon, J.H.1
Lee, W.L.2
Tartaro, K.R.3
-
38
-
-
31744435976
-
BEAMing up for detection and quantification of rare sequence variants
-
Li M, Diehl F, Dressman D, et al. BEAMing up for detection and quantification of rare sequence variants. Nat Methods 2006; 3:95-97. Approach to increase the DNA copy number on beads generated by BEAMing.
-
(2006)
Nat Methods
, vol.3
, pp. 95-97
-
-
Li, M.1
Diehl, F.2
Dressman, D.3
-
39
-
-
24044455869
-
Genome sequencing in microfabricated high-density picolitre reactors
-
Margulies M, Egholm M, Altman WE, et al. Genome sequencing in microfabricated high-density picolitre reactors. Nature 2005; 437:376-380. Application of a new highly parallel sequencing system for the resequencing of the mycoplasma genome.
-
(2005)
Nature
, vol.437
, pp. 376-380
-
-
Margulies, M.1
Egholm, M.2
Altman, W.E.3
-
40
-
-
33745926178
-
Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing
-
Thomas RK, Nickerson E, Simons JF, et al. Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing. Nat Med 2006; 12:852-855. Application of 454 sequencer for the detection and quantification of EGFR mutations in lung cancer biopsies.
-
(2006)
Nat Med
, vol.12
, pp. 852-855
-
-
Thomas, R.K.1
Nickerson, E.2
Simons, J.F.3
-
41
-
-
24644462173
-
Accurate multiplex polony sequencing of an evolved bacterial genome
-
Shendure J, Porreca GJ, Reppas NB, et al. Accurate multiplex polony sequencing of an evolved bacterial genome. Science 2005; 309:1728-1732. Application of new beads-based sequencing technology for the resequencing of Escherichia coli.
-
(2005)
Science
, vol.309
, pp. 1728-1732
-
-
Shendure, J.1
Porreca, G.J.2
Reppas, N.B.3
-
42
-
-
21444447966
-
Operating characteristics of prostate-specific antigen in men with an initial PSA level of 3.0 ng/ml or lower
-
Thompson IM, Ankerst DP, Chi C, et al. Operating characteristics of prostate-specific antigen in men with an initial PSA level of 3.0 ng/ml or lower. JAMA 2005; 294:66-70.
-
(2005)
JAMA
, vol.294
, pp. 66-70
-
-
Thompson, I.M.1
Ankerst, D.P.2
Chi, C.3
-
43
-
-
33745938246
-
New technologies and directed agents for applications of cancer imaging
-
Atri M. New technologies and directed agents for applications of cancer imaging. J Clin Oncol 2006; 24:3299-3308.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3299-3308
-
-
Atri, M.1
-
44
-
-
0036515416
-
Emerging molecular markers of cancer
-
Sidransky D. Emerging molecular markers of cancer. Nat Rev Cancer 2002; 2:210-219.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 210-219
-
-
Sidransky, D.1
-
45
-
-
28544446695
-
Biomarkers in cancer staging, prognosis and treatment selection
-
Ludwig JA, Weinstein JN. Biomarkers in cancer staging, prognosis and treatment selection. Nat Rev Cancer 2005; 5:845-856. Review about advances in biomarker development.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 845-856
-
-
Ludwig, J.A.1
Weinstein, J.N.2
-
46
-
-
15944404601
-
The development of imatinib as a therapeutic agent for chronic myeloid leukemia
-
Deininger M, Buchdunger E, Druker BJ. The development of imatinib as a therapeutic agent for chronic myeloid leukemia. Blood 2005; 105:2640-2653.
-
(2005)
Blood
, vol.105
, pp. 2640-2653
-
-
Deininger, M.1
Buchdunger, E.2
Druker, B.J.3
-
47
-
-
33745603988
-
Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: Review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results
-
Hughes T, Deininger M, Hochhaus A, et al. Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results. Blood 2006; 108:28-37.
-
(2006)
Blood
, vol.108
, pp. 28-37
-
-
Hughes, T.1
Deininger, M.2
Hochhaus, A.3
-
48
-
-
2942607684
-
Quantification of plasma Epstein-Barr virus DNA in patients with advanced nasopharyngeal carcinoma
-
Lin JC, Wang WY, Chen KY, et al. Quantification of plasma Epstein-Barr virus DNA in patients with advanced nasopharyngeal carcinoma. N Engl J Med 2004; 350:2461-2470.
-
(2004)
N Engl J Med
, vol.350
, pp. 2461-2470
-
-
Lin, J.C.1
Wang, W.Y.2
Chen, K.Y.3
-
49
-
-
15544388390
-
Circulating and disseminated tumor cells
-
Braun S, Naume B. Circulating and disseminated tumor cells. J Clin Oncol 2005; 23:1623-1626.
-
(2005)
J Clin Oncol
, vol.23
, pp. 1623-1626
-
-
Braun, S.1
Naume, B.2
-
50
-
-
33646710101
-
Tumor cell detection in peripheral blood and bone marrow
-
Zach O, Lutz D. Tumor cell detection in peripheral blood and bone marrow. Curr Opin Oncol 2006; 18:48-56.
-
(2006)
Curr Opin Oncol
, vol.18
, pp. 48-56
-
-
Zach, O.1
Lutz, D.2
-
51
-
-
33646367930
-
Quantitative assessment of DNA methylation: Potential applications for disease diagnosis, classification, and prognosis in clinical settings
-
Brena RM, Huang TH, Plass C. Quantitative assessment of DNA methylation: potential applications for disease diagnosis, classification, and prognosis in clinical settings. J Mol Med 2006; 84:365-377. Review about the quantification of methylated DNA in cancer patients.
-
(2006)
J Mol Med
, vol.84
, pp. 365-377
-
-
Brena, R.M.1
Huang, T.H.2
Plass, C.3
-
52
-
-
27644597171
-
Circulating nucleic acids in plasma or serum (CNAPS) as prognostic and predictive markers in patients with solid neoplasias
-
Goebel G, Zitt M, Zitt M, et al. Circulating nucleic acids in plasma or serum (CNAPS) as prognostic and predictive markers in patients with solid neoplasias. Dis Markers 2005; 21:105-120. Review about the value of detecting mutant DNA in the circulation of cancer patients.
-
(2005)
Dis Markers
, vol.21
, pp. 105-120
-
-
Goebel, G.1
Zitt, M.2
Zitt, M.3
|