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Volumn 20, Issue 5, 2006, Pages 303-310

Translational science in medicine: Implications for the pharmaceutical industry

Author keywords

[No Author keywords available]

Indexed keywords

ANTIESTROGEN; BACLOFEN; BIOLOGICAL MARKER; CORTICOSTERONE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; GLUCOCORTICOID; HYDROCORTISONE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERLEUKIN 6; NONSTEROID ANTIINFLAMMATORY AGENT; PENICILLIN G; ROSUVASTATIN; THROMBOXANE; TRASTUZUMAB;

EID: 33845350345     PISSN: 13649027     EISSN: 13649027     Source Type: Journal    
DOI: 10.2165/00124363-200620050-00004     Document Type: Review
Times cited : (9)

References (19)
  • 1
    • 85030602838 scopus 로고    scopus 로고
    • Available from URL: [Accessed 2006 Jun 15]
    • US FDA. The critical path to new medical products [online]. Available from URL: http://www.fda.gov/oc/initiatives/criticalpath/ [Accessed 2006 Jun 15]
    • The Critical Path to New Medical Products [Online]
  • 2
    • 4344645978 scopus 로고    scopus 로고
    • Can the pharmaceutical industry reduce attrition rates?
    • Kola I, Landis J. Can the pharmaceutical industry reduce attrition rates? Nature Rev Drug Discov 2004; 3: 711-5
    • (2004) Nature Rev Drug Discov , vol.3 , pp. 711-715
    • Kola, I.1    Landis, J.2
  • 4
    • 33845357648 scopus 로고
    • How I discovered penicillin
    • (Oporto) May 6
    • Fleming A. How I discovered penicillin. J Med (Oporto) 1950 May 6; 15 (380): 683
    • (1950) J Med , vol.15 , Issue.380 , pp. 683
    • Fleming, A.1
  • 5
    • 84870687317 scopus 로고    scopus 로고
    • Available from URL: [Accessed 2006 Aug 29]
    • Encyclopaedia Britannica [online]. Available from URL: http://www.britannica.com/eb/article-9066286 [Accessed 2006 Aug 29]
    • Encyclopaedia Britannica [Online]
  • 6
    • 0038004636 scopus 로고    scopus 로고
    • Clinical biomarkers in drug discovery and development
    • Frank R, Hargreaves R. Clinical biomarkers in drug discovery and development. Nat Rev Drug Discov 2003; 2: 566-80
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 566-580
    • Frank, R.1    Hargreaves, R.2
  • 7
    • 2642536741 scopus 로고    scopus 로고
    • Inflammation, immunity, and HMG-CoA reductase inhibitors: Statins as antiinflammatory agents?
    • Schonbeck U, Libby P. Inflammation, immunity, and HMG-CoA reductase inhibitors: statins as antiinflammatory agents? Circulation 2004; 109 (21 Suppl. 1): II18-26
    • (2004) Circulation , vol.109 , Issue.21 SUPPL. 1
    • Schonbeck, U.1    Libby, P.2
  • 8
    • 0035100888 scopus 로고    scopus 로고
    • Biomarkers and surrogate endpoints. Preferred definitions and conceptual framework
    • Biomarkers Definitions Working Group
    • Biomarkers Definitions Working Group Biomarkers and surrogate endpoints. Preferred definitions and conceptual framework. Clin Pharmacol Ther 2001; 69: 89-95
    • (2001) Clin Pharmacol Ther , vol.69 , pp. 89-95
  • 9
    • 0037384066 scopus 로고    scopus 로고
    • Use of biomarkers from drug discovery through clinical practice: Report of the Ninth European Federation of Pharmaceutical Sciences Conference on Optimizing Drug Development
    • Rolan P, Atkinson Jr AJ, Lesko LJ, et al. Use of biomarkers from drug discovery through clinical practice: report of the Ninth European Federation of Pharmaceutical Sciences Conference on Optimizing Drug Development. Clin Pharmacol Ther 2003; 73: 284-91
    • (2003) Clin Pharmacol Ther , vol.73 , pp. 284-291
    • Rolan, P.1    Atkinson Jr., A.J.2    Lesko, L.J.3
  • 10
    • 33645388385 scopus 로고    scopus 로고
    • Translational medicine: Can it really facilitate the transition of research "from bench to bedside"?
    • Feb
    • Wehling M. Translational medicine: can it really facilitate the transition of research "from bench to bedside"? Eur J Clin Pharmacol 2006 Feb; 62 (2): 91-5
    • (2006) Eur J Clin Pharmacol , vol.62 , Issue.2 , pp. 91-95
    • Wehling, M.1
  • 11
    • 85069074677 scopus 로고    scopus 로고
    • Rosuvastatin treatment arrests the progression of carotid atherosclerosis in moderately hypercholesterolaemic subjects: A high-resolution magnetic resonance imaging trial
    • Apr 23-26; Prague, Czech Republic
    • Hatsukami TS, Saam T, Yuyan C, et al. Rosuvastatin treatment arrests the progression of carotid atherosclerosis in moderately hypercholesterolaemic subjects: a high-resolution magnetic resonance imaging trial. 75th European Atherosclerosis Society Congress; 2005 Apr 23-26; Prague, Czech Republic
    • (2005) 75th European Atherosclerosis Society Congress
    • Hatsukami, T.S.1    Saam, T.2    Yuyan, C.3
  • 12
    • 33745004785 scopus 로고    scopus 로고
    • Biomarkers of cardiovascular disease: Molecular basis and practical considerations
    • Vasan R. Biomarkers of cardiovascular disease: molecular basis and practical considerations. Circulation 2006; 113: 2335-62
    • (2006) Circulation , vol.113 , pp. 2335-2362
    • Vasan, R.1
  • 13
    • 85069081828 scopus 로고    scopus 로고
    • Available from URL: [Accessed 2006 Jun 15]
    • Early Detection Research Network. Science components [online]. Available from URL: http://edrn.nci.nih.gov/about-edrn/scicomponents [Accessed 2006 Jun 15]
    • Science Components [Online]
  • 15
    • 14844344010 scopus 로고    scopus 로고
    • The agony and ecstasy of "OMIC" technologies in drug development
    • Bilello JA. The agony and ecstasy of "OMIC" technologies in drug development. Curr Mol Med 2005; 5: 39-52
    • (2005) Curr Mol Med , vol.5 , pp. 39-52
    • Bilello, J.A.1
  • 16
    • 18244370796 scopus 로고    scopus 로고
    • How molecular profiling could revolutionize drug discovery
    • Stoughton RB, Friend SH. How molecular profiling could revolutionize drug discovery. Nat Rev Drug Discov 2005; 4: 345-50
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 345-350
    • Stoughton, R.B.1    Friend, S.H.2
  • 17
    • 0141757445 scopus 로고    scopus 로고
    • B agonist baclofen in patients with symptoms and duodeno-gastro-oesophageal reflux refractory to proton pump inhibitors
    • B agonist baclofen in patients with symptoms and duodeno-gastro-oesophageal reflux refractory to proton pump inhibitors. Gut 2003; 52: 1397-402
    • (2003) Gut , vol.52 , pp. 1397-1402
    • Koek, G.H.1    Sifrim, D.2    Lerut, T.3
  • 18
    • 0035712665 scopus 로고    scopus 로고
    • Maximizing the response to herceptin therapy through optimal use and patient selection
    • Leyland-Jones B. Maximizing the response to herceptin therapy through optimal use and patient selection. Anticancer Drugs 2001; 12 Suppl. 4: S11-7
    • (2001) Anticancer Drugs , vol.12 , Issue.SUPPL. 4
    • Leyland-Jones, B.1
  • 19
    • 85069058709 scopus 로고    scopus 로고
    • Available from URL: [Accessed 2006 Jun 15]
    • CenterWatch. Drugs approved by FDA (2006) [online]. Available from URL: http://www.centerwatch.com/patient/drugs/druglist.html [Accessed 2006 Jun 15]
    • Drugs Approved by FDA (2006) [Online]


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.