A phage-displayed single chain variable fragment that interacts with hepatitis B core antigen: Library construction, selection and diagnosis

Journal of Clinical Virology

Volumn 38, Issue 1, 2007, Pages 49-56

  Tan, Geok Hun ^a   Yusoff, Khatijah ^a   Seow, Heng Fong ^a   Tan, Wen Siang ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

Combinatorial antibody libraries; Diagnosis; Hepatitis B core antigen; Phage display; Phage ELISA

Indexed keywords

CYCLOPEPTIDE; HEPATITIS B CORE ANTIGEN; RNA; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY ISOLATION; ANTIBODY LIBRARY; ANTIGEN BINDING; ANTIGEN DETECTION; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; DRUG SCREENING; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEPATITIS B; MOLECULAR CLONING; MOUSE; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; RNA EXTRACTION; SPLEEN CELL;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, VIRAL; ANTIBODY SPECIFICITY; BASE SEQUENCE; FEMALE; HEPATITIS B; HEPATITIS B CORE ANTIGENS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY;

EID: 33845345916     PISSN: 13866532     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcv.2006.09.010     Document Type: Article

References (28)

1. Barbas III C.F., Kang A.S., Lerner R.A., and Benkovic S.J. Assembly of combinatorial antibody libraries on phage surface: the gene III site. Proc Natl Acad Sci USA 88 (1991) 7978-7982
2. Bredehorst R., von Wulffen H., and Granato C. Quantitation of hepatitis B virus (HBV) core antigen in serum in the presence of antibodies to HBV core antigen: comparison with assays of serum HBV DNA, DNA polymerase, and HBV e antigen. J Clin Microbiol 21 (1985) 593-598
3. Bredehorst R., von Wulffen H., and Granato C. Quantitation of hepatitis B virus (HBV) core antigen in serum in the presence of antibodies to HBV core antigen: comparison with assays of serum HBV DNA, DNA polymerase, and HBV e antigen. J Clin Microbiol 21 (1985) 593-598
4. Cao T., Lazdina U., Desombere I., Vanlandschoot P., Milich D.R., Sallberg M., and Leroux-Roels G. Hepatitis B virus core antigen binds and activates naïve human B cells in vivo: studies with a human PBL-NOD/SCID mouse model. J Virol 75 (2001) 6359-6366
5. Cohen B.J., and Richmond J.E. Electron microscopy of hepatitis B core antigen synthesized in Escherichia coli. Nature 296 (1982) 677-678
6. Crowther R.A., Kiselev N.A., Böttcher B., Berriman J.A., Borisova G.P., Ose V., and Pumpens P. Three-dimensional structure of hepatitis B virus core particles determined by electron cryomicroscopy. Cell 77 (1994) 943-950
7. Dyson M.R., and Murray K. Selection of peptide inhibitors of interactions involved in complex protein assemblies: association of the core and surface antigens of hepatitis B virus. Proc Natl Acad Sci USA 92 (1995) 2194-2198
8. Freeman R., and Hambling M.H. Routine use of counter-immunoeletrophoresis test for detecting antibody to hepatitis B virus core antigen. J Clin Pathol 31 (1978) 832-836
9. Ganem D. Assembly of hepadnaviral virions and subviral particles. Curr Top Microbiol Immunol 168 (1991) 61-63
10. Glockshuber R., Malia M., Pfitzinger I., and Pluckthun A. A comparison of strategies to stabilize immunoglobulin Fv fragments. Biochemistry 29 (1990) 1362-1367
11. Hatzakis A., Magiorkinis E., and Haida C. HBV virological assessment. J Hepatol 44 (2006) S71-S76
12. Hendricks D.A., Stowe B.J., Hoo B.S., Kolberg J.L., Irvine B.D., Neuwald P.D., Urdea M.S., and Perrillo R.P. Quantitation of HBV DNA in human serum using a branched DNA (bDNA) signal amplification assay. Am J Clin Pathol 104 (1995) 537-546
13. Hwang G.-Y., Lin C.-Y., Huang L.-M., Wang Y.-H., Wang J.-C., Hsu C.-T., Yang S.-S., and Wu C.-C. Detection of the hepatitis B virus X-protein (HBx) antigen and anti-HBx antibodies in cases of human hepatocellular carcinoma. J Clin Microbiol 41 (2003) 5598-5603
14. Ho K.L., Yusoff K., Seow H.F., and Tan W.S. Selection of high affinity ligands to hepatitis B core antigen from a phage-displayed cyclic peptide library. J Med Virol 69 (2003) 27-32
15. Jung M.-C., and Pape G.R. Immunology of hepatitis B infection. Lancet 2 (2002) 43-50
16. Kabat E.A., Wu T.T., Perry H.M., Gottesman K.S., and Foeller C. Sequences of proteins of immunological interest. 5th ed. (1991), Public Health Service, NIH, Washington, DC
17. Kimura T., Rokuhara A., Matsumoto A., Yagi S., Tanaka E., Kiyosawa K., and Maki N. New enzyme immunoassay for detection of hepatitis B virus core antigen (HBcAg) and relation between levels of HBcAg and HBV DNA. J Clin Microbiol 41 (2003) 1901-1906
18. Milich D.R., Schodel F., Hughes J.L., Jones J.E., and Peterson D.L. The hepatitis B virus core and e antigens elicit different Th cell subsets: antigen structure can affect Th cell phenotype. J Virol 71 (1997) 2192-2201
19. Milich D.R., and McLachlan A. The nucleocapsid of hepatitis B virus is both a T-cell independent and a T-cell dependent antigen. Science 234 (1986) 1398-1404
20. Pennell, C.A. Restricted Ig variable region gene expression among Ly-1+B cell lymphomas; 1988 [ http://www.ncbi.nlm.nih.gov/blast/Blast.cgi, accessed on 18 November 2005].
21. Pushko P., Sallberg M., Borisova G., Ruden U., Bichko V., Wahren B., Pumpens P., and Magnius L. Identification of hepatitis B virus core protein regions exposed or internalized at the surface of HBcAg particles by scanning with monoclonal antibodies. J Virol 202 (1994) 912-920
22. Rizzetto M., Shih J.W., Verme G., and Gerin J.L.A. Radioimmunoassay for HBcAg in the sera of HBsAg carriers: serum HBcAg, liver HBcAg immunofluorescence as markers of chronic liver disease. Gastroenterology 80 (1981) 1420-1427
23. Roseman A.M., Berriman J.A., Wynne S.A., Butler P.J., and Crowther R.A. A structural model for maturation of the hepatitis B virus core. Proc Natl Acad Sci USA 102 (2005) 15821-15826
24. Sambrook J., Fritsch E.F., and Maniatis T. Molecular cloning: a laboratory manual (1989), Cold Spring Harbor Laboratory Press, Cold Spring Harbour, New York
25. Salfeld J., Pfaff E., Noah M., and Schaller H. Antigenic determinants and functional domains in core antigen and e antigen from hepatitis B virus. J Virol 63 (1989) 798-808
26. Tan W.S., Tan G.H., Yusoff K., and Seow H.F. A phage-displayed cyclic peptide that interacts tightly with the immunodominant region of hepatitis B surface antigen. J Clin Virol 34 (2005) 35-41
27. Usuda S., Okamoto H., Tsuda F., Tanaka T., Miyakawa Y., and Mayumi M. An enzyme-linked immunosorbent assay with monoclonal antibodies for the determination of phosphorylated hepatitis B core protein (p21c) in serum. J Virol Methods 72 (1998) 95-103
28. Wynne S.A., Crowther R.A., and Leslie A.G.W. The crystal structure of the human hepatitis B virus capsid. Mol Cell 3 (1999) 771-780