Identification of transgene integration loci of different highly expressing recombinant CHO cell lines by FISH

Cytotechnology

Volumn 51, Issue 3, 2006, Pages 171-182

  Lattenmayer, Christine ^a   Loeschel, Martina ^c   Steinfellner, Willibald ^b   Trummer, Evelyn ^a   Mueller, Dethardt ^b   Schriebl, Kornelia ^a   Vorauer Uhl, Karola ^b   Katinger, Hermann ^b,c   Kunert, Renate ^b  

^a Austrian Center of Biopharmaceutical Technology   (Austria)

^b UNIVERSITY OF AGRICULTURAL SCIENCES   (Austria)

^c POLYMUN SCIENTIFIC IMMUNBIOLOGISCHE FORSCHUNG GMBH   (Austria)

Author keywords

FISH; Giemsa Trypsin banding; Insertion locus; Integration site; Recombinant CHO

Indexed keywords

METHOTREXATE; PROTEIN; TRYPSIN;

ANIMAL CELL; ARTICLE; CHO CELL; CHROMOSOME; CONTROLLED STUDY; EXPRESSION VECTOR; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE INSERTION; GENE LOCATION; GENE LOCUS; GENE TARGETING; GENETIC SELECTION; GENOME; GIEMSA STAIN; MARKER GENE; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; RECOMBINANT CELL LINE; TRANSCRIPTION REGULATION; TRANSGENE;

EXOGENE;

EID: 33845309979     PISSN: 09209069     EISSN: 15730778     Source Type: Journal    
DOI: 10.1007/s10616-006-9029-0     Document Type: Article

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