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With the corresponding simple diol TADDOL(Ph), we obtained only 52% conversion with 12% ee in the cyclopropanation of benzyl-protected cinnamyl alcohol.
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33845274432
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note
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In the cyclopropanation of the benzylated cinnamylic alcohol (substrate A with Shi's ligand (the dipeptide N-Boc-L-Val-L-Pro-OMe) 7% ee was obtained with 81% yield (unpublished results).
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