Is Western blot alone sufficient to confirm a reactive result of a fourth-generation HIV screening assay?

Swiss Medical Weekly

Volumn 136, Issue 41-42, 2006, Pages 672-673

  Dobec, Marinko ^a   Naegeli, Adrian ^b   Furrer, Kurt ^a   Kaeppeli, Franz ^a  

^a Medizinische Laboratorien Dr F Kaeppeli   (Switzerland)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIBODY; IMMUNOGLOBULIN G;

ADULT; CASE REPORT; CLINICAL FEATURE; DIAGNOSTIC PROCEDURE; ENZYME IMMUNOASSAY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INCIDENCE; INFECTION PREVENTION; LABORATORY TEST; LETTER; MALE; POLYMERASE CHAIN REACTION; PRACTICE GUIDELINE; SCREENING; SEROLOGY; SKIN DISEASE; WESTERN BLOTTING;

EID: 33845268628     PISSN: 14247860     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Letter

References (11)

1. Pilcher CD, Eron JJ, Galvin S, Gay C, Cohen MS. Acute HIV revisited: new opportunities for treatment and prevention. J Clin Invest. 2004;113:937-45.
2. Sterling TR, Chaisson RE. General clinical manifestations of human immunodeficiency virus infection (including the acute retroviral syndrome and oral, cutaneous, renal, ocular, and cardiac diseases). In: Mandel GL, Bennett JE, Dolin R, eds. Principles and practice of infectious diseases. 6th ed. Philadelphia: Churchill Livingstone, 2005:1546-66.
3. Weintrob AC, Giner J, Menezes P, Patrick E, Benjamin DK Jr, Lennox J, et al. Infrequent diagnosis of primary human immunodeficiency virus infection: missed opportunities in acute care settings. Arch Intern Med. 2003;163:2097-100.
4. Weber B, Thorstensson R, Tanprasert S, Schmitt U, Melchior W. Reduction of the diagnostic window in three cases of human immunodeficiency-1 subtype E primary infection with fourth-generation HIV screening assays. Vox Sang. 2003;85:73-9.
5. Ly TD, Laperche S, Brennan C, Vallari A, Ebel A, Hunt J, et al. Evaluation of the sensitivity and specificity of six HIV combined p24 antigen and antibody assays. J Virol Methods. 2004;122:185-94.
6. Fachkommision Labor und Diagnostik: Diagnostische Empfehlung. HIV-Testkonzept 2004: Neue Richtlinien zum Screening. BAG Bulletin 2004;10:168-70.
7. McElborough D. Importance of using an HIV Ag/Ab combined assay in a UK population at high risk of acquiring HIV infection. Commun Dis Public Health. 2004;7:312-4.
8. Pilcher CD, Fiscus SA, Nguyen TQ, Foust E, Wolf L, Williams D, et al. Detection of acute infections during HIV testing in North Carolina. N Engl J Med. 2005;352:1873-83.
9. Taylor MM, Hawkins K, Gonzalez A, Buchacz K, Aynalem G, Smith LV, et al. Use of the serologic testing algorithm for recent HIV seroconversion (STARHS) to identify recently acquired HIV infections in men with early syphilis in Los Angeles County. J Acquir Immune Defic Syndr. 2005;38:505-8.
10. Vanhems P, Voirin N, Philippe P, Hirschel B, Brassard J, Carr A, et al. The incubation period of acute retroviral syndrome as a multistep process: a parametric survival analysis. J Acquir Immune Defic Syndr. 2004;37:1529-33.
11. Schupbach J. SHCS and the laboratory diagnosis of HIV infection - from the development of the HIV Western blot to virus quantification and clinically relevant individual virus characterization. Ther Umsch. 2004;61:603-7.