Expression of p53 in aggressive and non-aggressive histologic variants of basal cell carcinoma

European Journal of Dermatology

Volumn 16, Issue 5, 2006, Pages 543-547

  Ansarin, Habib ^a   Daliri, Mina ^a   Soltani Arabshahi, Razieh ^a  

^a IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Basal cell carcinoma; Immunohistochemistry; Sun exposure; Tumor aggressiveness; Tumor suppressor protein p53

Indexed keywords

EOSIN; HEMATOXYLIN; MONOCLONAL ANTIBODY; PROTEIN P53;

ADULT; AGED; ARTICLE; BASAL CELL CARCINOMA; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IRAN; MALE; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SCORING SYSTEM; STAINING; TUMOR CELL; TUMOR CLASSIFICATION; UNIVERSITY HOSPITAL;

AGED; CARCINOMA, BASAL CELL; FEMALE; GENES, P53; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MUTATION; SKIN NEOPLASMS; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33845259371     PISSN: 11671122     EISSN: None     Source Type: Journal    
DOI: 10.1684/ejd.2006.0027     Document Type: Article

References (35)

1. Diepgen T, Mahler V. The epidemiology of skin cancer. Br J Dermatol 2002; 146(Suppl 61): 1-6.
2. Zanetti R, Rosso S, Martinez C, et al. The multicenter south European Helios study I. Skin characteristics and sunburns in basal and squamous cell carcinomas of the skin. Br J Cancer 1996; 73: 1440-6.
3. Walling HW, Fosko SW, Geraminejad PA, et al. Aggressive basal cell carcinoma: Presentation, pathogenesis, and management. Cancer Metastasis Rev 2004; 23: 389-402.
4. Dixon AY, Lee SH, McGregor DH. Factors predictive of recurrence of basal cell carcinomas. Am J Dermatopathol 1989; 11: 222-32.
5. Rippey JJ. Why classify basal cell carcinomas? Histopathology 1998; 32: 393-8.
6. Staibano S, Lo Muzio L, Pannone G, et al. Interaction between bcl-2 and P53 in neoplastic progression of basal cell carcinoma of the head and neck. Anticancer Res 2001; 21: 3757-64.
7. Healy E, Angus B, Lawrence CM, Rees JL. Prognostic value of Ki67 antigen expression in basal cell carcinomas. Br J Dermatol 1995; 133: 737-41.
8. Barbaud A, Simon M, Parache RM, Serre G. Immunohistochemical characterization of the differentiation state of basal cell carcinomas with special interest for infiltrating relapsing tumors. Eur J Dermatol 1998; 8: 320-4.
9. Panuncio A, Vignale R, Lopez G. Immunohistochemical study of nerve fibres in basal cell carcinoma. Eur J Dermatol 2003; 13: 250-3.
10. Ro YS, Cooper PN, Lee JA, et al. p53 protein expression in benign and malignant skin tumors. Br J Dermatol 1993; 128: 237-41.
11. Shea CR, McNutt NS, Volkenandt M, et al. Overexpression of p53 protein in basal cell carcinoma of human skin. Am J Pathol 1992; 141: 25-9.
12. Barbareschi M, Girlando S, Cristofolini P, et al. p53 protein expression in basal cell carcinoma. Histopathology 1992; 21: 579-81.
13. Barrett TL, Smith KJ, Hodge JJ, et al. Immunohistochemical nuclear staining for p53, PCNA, and Ki-67 in different histologic variants of basal cell carcinoma. J Am Acad Dermatol 1997; 37: 430-7.
14. Boonchai W, Walsh M, Cummings M, Chenevix-Trench G. Expression of p53 in arsenic-related and sporadic basal cell carcinoma. Arch Dermatol 2000; 136: 195-8.
15. Lacour JP. Carcinogenesis of basal cell carcinomas: genetics and molecular mechanisms. Br J Dermatol 2002; 146(Suppl 61): 17-9.
16. Shin DM, Lee JS, Lippman SM, et al. p53 expressions: predicting recurrence and second primary tumors in head and neck squamous cell carcinoma. J Natl Cancer Inst 1996; 88: 519-29.
17. De Rosa G, Staibano S, Barra E, et al. p53 Protein in aggressive and non-aggressive basal cell carcinoma. J Cutan Pathol 1993; 20: 429-34.
18. Auepemkiate S, Boonyaphiphat P, Thongsuksai P. p53 expression related to the aggressive infiltrative histopathological feature of basal cell carcinoma. Histopathology 2002; 40: 568-73.
19. Demirkan NC, Colakoglu N, Duzcan E. Value of p53 protein in biological behavior of basal cell carcinoma and in normal epithelia adjacent to carcinomas. Pathol Oncol Re 2000; 6: 272-4.
20. Bolshakov S, Walker CM, Strom SS, et al. p53 mutations in human aggressive and nonaggressive basal and squamous cell carcinomas. Clin Cancer Res 2003; 9: 228-34.
21. Edwards MJ, Thomas RC, Wong YL Retinoblastoma gene expression in human non-melanoma skin cancer. J Cutan Pathol 2003; 30: 479-85.
22. Kirkham N. Tumor and cysts of the epidermis. In: Lever's histopathology of the skin (Elder D, ed), 9th edn, Vol 2. Philadelphia: Lippincott Williams & Wilkins, 2005: 836-49.
23. Sexton M, Jones DB, Maloney ME. Histologic pattern analysis of basal cell carcinoma. J Am Acad Dermatol 1990; 23: 1118-26.
24. Mancuso M, Pazzaglia S, Tanori M, et al. Basal cell carcinoma and its development: insights from radiation-induced tumors in Ptch1-deficient mice. Cancer Res 2004; 64: 934-41.
25. Sloane JP. The value of typing basal cell carcinomas in predicting recurrence after surgical excision. Br J Dermatol 1977; 96: 127-33.
26. Jacobs GH, Rippey JJ, Altini M. Prediction of aggressive behavior in basal cell carcinoma. Cancer 1982; 49: 533-7.
27. Lang Jr. PG, Maize JC. Histologic evolution of recurrent basal cell carcinoma and treatment implications. J Am Acad Dermatol 1986; 14: 186-96.
28. Rippey JJ, Rippey E. Characteristics of incompletely excised basal cell carcinomas of the skin. Med J Aust 1997; 166: 581-3.
29. Leffell D, Headington JT, Wong DS, Swanson NA. Aggressive-growth basal cell carcinoma in young adults. Arch Dermatol 1991; 127: 1663-7.
30. Stephen CW, Lane DP. Mutant conformation of p53. Precise epitope mapping using a filamentous phage epitope library. J Mol Biol 1992; 225: 577.
31. Urano Y, Asano T, Yoshimoto K, et al. Frequent p53 accumulation in the chronically sun-exposed epidermis and clonal expansion of p53 mutant cells in the epidermis adjacent to basal cell carcinoma. J Invest Dermatol 1995; 104: 928-32.
32. Sliney DH. Geometrical assessment of ocular exposure to environmental UV radiation - implications for ophthalmic epidemiology. J Epidemiol 1999; 9(6 Suppl): S22-S32.
33. Birt B, Cowling I, Coyne S. UVR reflections at the surface of the eye. J Photochem Photobiol B 2004; 77: 71-7.
34. Mseddi M, Bouassida S, Marrekchi S, et al. Basal cell carcinoma of the scalp after radiation therapy for tinea capifis: 33 patients. Cancer Radiother 2004; 8: 270-3.
35. Staibano S, Lo Muzio L, Pannone G, et al. P53 and hMSH2 expression in basal cell carcinomas and malignant melanomas from photoexposed areas of head and neck region. Int J Oncol 2001; 19: 551-9.