Long-term variations in Human T Lymphotropic Virus (HTLV)-I and HTLV-II proviral loads and association with clinical data

Journal of Infectious Diseases

Volumn 194, Issue 11, 2006, Pages 1557-1564

  Kwaan, Nicholas ^a,b   Lee, Tzong Hae ^b   Chafets, Daniel M ^b   Nass, Catharie ^d   Newman, Bruce ^d   Smith, James ^e   Garratty, George ^d   Murphy, Edward L ^b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BLOOD SYSTEMS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d AMERICAN RED CROSS BLOOD SERVICES   (United States)

^e Oklahoma Blood Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AFRICAN AMERICAN; AGED; ALCOHOL CONSUMPTION; ARTICLE; BLADDER DISEASE; COHORT ANALYSIS; DISEASE COURSE; FEMALE; HUMAN; HUMAN CELL; HUMAN T CELL LEUKEMIA VIRUS 1; HUMAN T CELL LEUKEMIA VIRUS 2; KIDNEY INFECTION; MAJOR CLINICAL STUDY; MALE; NEUROPATHOLOGY; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROVIRUS; REAL TIME POLYMERASE CHAIN REACTION; SMOKING; VIRUS LOAD; VIRUS PATHOGENESIS;

ADULT; ALCOHOL DRINKING; COHORT STUDIES; DISEASE PROGRESSION; DNA, VIRAL; ETHNIC GROUPS; FEMALE; HTLV-I INFECTIONS; HTLV-II INFECTIONS; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMAN T-LYMPHOTROPIC VIRUS 2; HUMANS; KIDNEY; LEUKOCYTES, MONONUCLEAR; LOGISTIC MODELS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDIES; PROVIRUSES; SMOKING; TIME FACTORS; URINARY BLADDER; VIRAL LOAD;

EID: 33845218657     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/508899     Document Type: Article

References (39)

1. Gallo RC. The first human retrovirus. Sci Am 1986; 255:88-98.
2. Miyoshi I, Fujishita M, Taguchi H, Matsubayashi K, Miwa N, Tanioka Y. Natural infection in non-human primates with adult T-cell leukemia virus or a closely related agent. Int J Cancer 1983; 32:333-6.
3. Poiesz BJ, Ruscetti FW, Gazdar AF, Bunn PA, Minna JD, Gallo RC. Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc Natl Acad Sci USA 1980; 77:7415-9.
4. Yoshida M, Miyoshi I, Hinuma Y. Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease. Proc Natl Acad Sci USA 1982; 79:2031-5.
5. Cann AJ, Chen ISY. Human T-cell leukemia virus types I and II. In: Fields B, ed. Virology. 2nd ed. New York: Raven Press, 1990:1501-27.
6. Wattel E, Vartanian JP, Pannetier C, Wain-Hobson S. Clonal expansion of human T-cell leukemia virus type 1-infected cells in asymptomatic and symptomatic carriers without malignancy. J Virol 1995; 69:2863-8.
7. Murphy EL, Lee T-H, Chafets D, et al. Higher human T lymphotropic virus (HTLV) provirus load is associated with HTLV-I versus HTLV-II, with HTLV-II subtype A versus B, and with male sex and a history of blood transfusion. J Infect Dis 2004; 190:504-10.
8. Gabet AS, Mortreux F, Talarmin A, et al. High circulating proviral load with oligoclonal expansion of HTLV-1 bearing T cells in HTLV-1 carriers with strongyloidiasis. Oncogene 2000; 19:4954-60.
9. Machuca A, Soriano V. In vivo fluctuation of HTLV-I and HTLV-II proviral load in patients receiving antiretroviral drugs. J Acquir Immune Defic Syndr 2000; 24:189-93.
10. Murphy EL, Grant RM, Kropp J, Oliveira A, Lee TH, Busch MP. Increased human T-lymphotropic virus type II proviral load following highly active retroviral therapy in HIV-coinfected patients. J Acquir Immune Defic Syndr 2003; 33:655-6.
11. Nagai M, Usuku K, Matsumoto W, et al. Analysis of HTLV-I proviral load in 202 HAM/TSP patients and 243 asymptomatic HTLV-I carriers: high proviral load strongly predisposes to HAM/TSP. J Neurovirol 1998; 4:586-93.
12. + T cells, and disease severity in HTLV-1-associated myelopathy (HAM/TSP). Blood 2002; 99:88-94.
13. Manns A, Miley WJ, Wilks RJ, et al. Quantitative proviral DNA and antibody levels in the natural history of HTLV-I infection. J Infect Dis 1999; 180:1487-93.
14. Okayama A, Stuver S, Matsuoka M, et al. Role of HTLV-1 proviral DNA load and clonality in the development of adult T-cell leukemia/lymphoma in asymptomatic carriers. Int J Cancer 2004; 110:621-5.
15. Taylor GP, Tosswill JH, Matutes E, et al. Prospective study of HTLV-I infection in an initially asymptomatic cohort. J Acquir Immune Defic Syndr 1999; 22:92-100.
16. Schreiber GB, Murphy EL, Horton JA, et al. Risk factors for human T-cell lymphotropic virus types I and II (HTLV-I and -II) in blood donors: the Retrovirus Epidemiology Donor Study. J Acquir Immune Defic Syndr Hum Retrovirol 1997; 14:263-71.
17. Lee TH, Chafets DM, Busch MP, Murphy EL. Quantitation of HTLV-I and II proviral load using real-time quantitative PCR with SYBR green chemistry. J Clin Virol 2004; 31:275-82.
18. Murphy EL, Wang B, Sacher RA, et al. Respiratory and urinary tract infections, arthritis, and asthma associated with HTLV-I and HTLV-II infection. Emerg Infect Dis 2004; 10:109-16.
19. Orland JR, Engstrom J, Fridey J, et al. Prevalence and clinical features of HTLV neurologic disease in the HTLV Outcomes Study. Neurology 2003; 61:1588-94.
20. Okayama A, Chen YM, Tachibana N, et al. High incidence of antibodies to HTLV-I tax in blood relatives of adult T cell leukemia patients. J Infect Dis 1991; 163:47-52.
21. Younis I, Khair L, Dundr M, Lairmore MD, Franchini G, Green PL. Repression of human T-cell leukemia virus type 1 and type 2 replication by a viral mRNA-encoded posttranscriptional regulator. J Virol 2004; 78:11077-83.
22. Daenke S, Kermode AG, Hall SE, et al. High activated and memory cytotoxic T-cell responses to HTLV-1 in healthy carriers and patients with tropical spastic paraparesis. Virology 1996; 217:139-46.
23. Asquith B, Mosley AJ, Barfield A, et al. A functional CD8+ cell assay reveals individual variation in CD8+ cell antiviral efficacy and explains differences in human T-lymphotropic virus type 1 proviral load. J Gen Virol 2005; 86:1515-23.
24. Asquith B, Zhang Y, Mosley A, et al. Lymphocyte kinetics in HTLV-I infection (abstract O-49). AIDS Res Hum Retroviruses 2005; 21:454.
25. Tanaka G, Okayama A, Watanabe T, et al. The clonal expansion of human T lymphotropic virus type 1-infected T cells: a comparison between seroconverters and long-term carriers. J Infect Dis 2005; 191:1140-7.
26. Jeffery KJ, Usuku K, Hall SE, et al. HLA alleles determine human T-lymphotropic virus-I (HTLV-I) proviral load and the risk of HTLV-I-associated myelopathy. Proc Natl Acad Sci USA 1999; 96:3848-53.
27. Nitta T, Tanaka M, Sun B, Hanai S, Miwa M. The genetic background as a determinant of human T-cell leukemia virus type 1 proviral load. Biochem Biophys Res Commun 2003; 309:161-5.
28. Sonoda J, Koriyama C, Yamamoto S, et al. HTLV-1 provirus load in peripheral blood lymphocytes of HTLV-1 carriers is diminished by green tea drinking. Cancer Sci 2004; 95:596-601.
29. Boyadjieva N, Dokur M, Advis JP, Meadows GG, Sarkar DK. Chronic ethanol inhibits NK cell cytolytic activity: role of opioid peptide beta-endorphin. J Immunol 2001; 167:5645-52.
30. Starkenburg S, Munroe ME, Waltenbaugh C. Early alteration in leukocyte populations and Th1/Th2 function in ethanol-consuming mice. Alcohol Clin Exp Res 2001;25:1221-30.
31. Barbour SE, Nakashima K, Zhang JB, et al. Tobacco and smoking: environmental factors that modify the host response (immune system) and have an impact on periodontal health. Crit Rev Oral Biol Med 1997; 8:437-60.
32. Tollerud DJ, Clark JW, Brown LM, et al. The effects of cigarette smoking on T cell subsets: a population-based survey of healthy Caucasians. Am Rev Respir Dis 1989; 139:1446-51.
33. Jezewska E, Dworacki G, Skrzypczak A, Zeromski J. Surface antigens and cytotoxic natural killer cell (NK) activity of blood lymphocytes in heavy cigarette smokers. Arch Geschwulstforsch 1990; 60:187-92.
34. Tollerud DJ, Brown LM, Blattner WA, Mann DL, Pankiw-Trost L, Hoover RN. T cell subsets in healthy black smokers and nonsmokers: evidence for ethnic group as an important response modifier. Am Rev Respir Dis 1991; 144:612-6.
35. Miller LG, Goldstein G, Murphy M, Ginns LC. Reversible alterations in immunoregulatory T cells in smoking: analysis by monoclonal antibodies and flow cytometry. Chest 1982; 82:526-9.
36. Lezin A, Olindo S, Olière S, et al. Human T lymphotropic virus type I (HTLV-I) proviral load in cerebrospinal fluid: a new criterion for the diagnosis of HTLV-I-associated myelopathy/tropical spastic paraparesis? J Infect Dis 2005; 191:1830-4.
37. Takenouchi N, Yamano Y, Usuku K, Osame M, Izumo S. Usefulness of proviral load measurement for monitoring of disease activity in individual patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis. J Neurovirol 2003; 9:29-35.
38. Matsuzaki T, Nakagawa M, Nagai M, et al. HTLV-I proviral load correlates with progression of motor disability in HAM/TSP: analysis of 239 HAM/TSP patients including 64 patients followed up for 10 years. J Neurovirol 2001; 7:228-34.
39. Kiwaki T Umehara F, Arimura Y, et al. The clinical and pathological features of peripheral neuropathy accompanied with HTLV-I associated myelopathy. J Neurol Sci 2003; 206:17-21.