Nano-mesosphere drug carriers for localized cancer chemotherapy

2006 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2006 Technical Proceedings

Volumn 2, Issue , 2006, Pages 1-4

  Goldberg, E P ^a   Almond, B A ^a   Hadba, A R ^a   Cuevas, B J ^a   York, A ^a   Enriquez, I ^a  

^a University of Florida   (United States)

Author keywords

Intratumoral chemotherapy; Local drug delivery; Nano mesospheres

Indexed keywords

BIODEGRADATION; DRUG PRODUCTS; NANOSTRUCTURED MATERIALS; ONCOLOGY; PROTEINS; TOXICITY; TUMORS;

CANCER DRUGS; DRUG CARRIERS; INTRATUMORAL CHEMOTHERAPY; LOCAL DRUG DELIVERY; MESOSPHERE; SYSTEMIC TOXICITY; THERAPEUTIC ACTIVITY;

CHEMOTHERAPY;

EID: 33845209147     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (10)

1. SEER Cancer Statistics Review (2001), 1973-1998. National Cancer Institute, Bethesda, MD
2. Breast cancer facts and figures (2002) 2001-2002. American Cancer Society, Atlanta, GA
3. Goldberg, EP, Hadba, AR, Almond, BA, Marotta, JS, Intratumoral cancer chemotherapy and immunotherapy: opportunities for nonsystemic pre-operative drug delivery. J Pharm Pharmacol (2002) 54:159-180
4. Baitchev, G, Gorchev, G, Deliisky, T, Popovska, S, Raitcheva, TZ, Perioperative locoregional application of mitoxantrone in patients with early breast carcinoma. (2001) J Chemother 13:440-3
5. Faulds, D, Balfour, JA, Chrisp, P, Langtry, HD, Mitoxantrone: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the chemotherapy of cancer. (1991) Drugs 41:400-449
6. Celikoglu, F, Celikoglu, SI, Goldberg, EP, Intratumoral cancer therapy through a flexible fiber optic bronchoscope. (2004) J Bronchoscopy 11:260-265
7. Corbett, TH, Griswold, DP, Roberts, BJ, Peckham, JC, Schabel, FM, Biology and therapeutic response of a mouse mammary adenocarcinoma (16/C) and its potential as a model for surgical adjuvant chemotherapy. (1978) Cancer Treat Rep 62: 1471-88
8. Hadba, AR, Synthesis, Properties and In Vivo Evaluation of Sustained Release Albumin-Mitoxantrone Microsphere Formulations for Non-systemic Treatment of Breast Cancer and Other High Mortality Cancers. 2001 Dissertation University of Florida., Gainesville, FL
9. Hadba, AR, Marotta, JS, Goldberg, EP. Effect of loading method on drug content and in vitro release of mitoxantrone from albumin microspheres. Trans 6th World Biomaterials Congress, 2000 p. 770
10. Knepp, WA, Jayakrishnan, A, Quigg, JM, Sitren, HS, Bagnall, JJ, Goldberg, EP, Synthesis, properties, and intratumoral evaluation of mitoxantrone-loaded casein microspheres in Lewis lung carcinoma. J Pharm Pharmacol (1993) 45: 887-91