Immune response to pneumococcal polysaccharides 4 and 14 in elderly and young adults. I Antibody concentrations, avidity and functional activity

Immunity and Ageing

Volumn 2, Issue , 2005, Pages

  Kolibab, Kris ^a   Smithson, S Louise ^a   Shriner, Anne K ^a   Khuder, Sadik ^a   Romero Steiner, Sandra ^b   Carlone, George M ^b   Westerink, M A Julie ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL VACCINE; CROSS REACTING ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; PNEUMOCOCCUS POLYSACCHARIDE 14 VACCINE; PNEUMOCOCCUS POLYSACCHARIDE 4 VACCINE; PNEUMOCOCCUS VACCINE;

ADULT; AGED; AGING; ANTIBODY AFFINITY; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ANTIBODY TITER; ANTIGEN ANTIBODY REACTION; ARTICLE; BACTERIAL CELL WALL; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION COEFFICIENT; DRUG BLOOD LEVEL; DRUG EFFICACY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNE RESPONSE; INFECTION RISK; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; SEROTYPE; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE;

EID: 33845195716     PISSN: 17424933     EISSN: None     Source Type: Journal    
DOI: 10.1186/1742-4933-2-10     Document Type: Article

References (28)

1. Vlasich C: Pneumococcal infection and vaccination in the elderly. Vaccine 2001, 19:2233-2237.
2. Sisk JE, Moskowitz AJ, Whang W, Lin JD, Fedson DS, McBean AM, Plouffe JF, Cetron MS, Butler JC: Cost-effectiveness of vaccination against pneumococcal bacteremia among elderly people. Jama 1997, 278:1333-1339.
3. Ruiz-Gonzalez A, Falguera M, Nogues A, Rubio-Caballero M: Is Streptococcus pneumoniae the leading cause of pneumonia of unknown etiology? A microbiologic study of lung aspirates in consecutive patients with community-acquired pneumonia. Am J Med 1999, 106:385-390.
4. Marrie TJ: Community-acquired pneumonia in the elderly. Clin Infect Dis 2000, 31:1066-1078.
5. Jackson LA, Neuzil KM, Yu O, Benson P, Barlow WE, Adams AL, Hanson CA, Mahoney LD, Shay DK, Thompson WW: Effectiveness of pneumococcal polysaccharide vaccine in older adults. N Engl J Med 2003, 348:1747-1755.
6. Bruyn GA, Zegers BJ, van Furth R: Mechanisms of host defense against infection with Streptococcus pneumoniae. Clin Infect Dis 1992, 14:251-262.
7. Austrian R: Some observations on the pneumococcus and on the current status of pneumococcal disease and its prevention. Rev Infect Dis 1981, 3:S1-17.
8. Butler JC, Breiman RF, Campbell JF, Lipman HB, Broome CV, Facklam RR: Pneumococcal polysaccharide vaccine efficacy. An evaluation of current recommendations. JAMA 1993, 270:1826-1831.
9. Robbins JB, Austrian R, Lee CJ, Rastogi SC, Schiffman G, Henrichsen J, Makela PH, Broome CV, Facklam RR, Tiesjema RH, et al.: Considerations for formulating the second-generation pneumococcal capsular polysaccharide vaccine with emphasis on the cross-reactive types within groups. J Infect Dis 1983, 148:1136-1159.
10. Rubins JB, Janoff EN: Pneumococcal disease in the elderly: what is preventing vaccine efficacy? Drugs Aging 2001, 18:305-311.
11. Hirschmann JV, Lipsky BA: The pneumococcal vaccine after 15 years of use [see comments]. Arch Intern Med 1994, 154:373-377.
12. Musher DM, Chapman AJ, Gorce A, Jonsson S, Briles D, Banghu RE: Natural and vaccine-related immunity to Streptococcus pneumoniae. J Infect Dis 1986, 154:245-256.
13. Siber GR, Priehs C, Madore D: Standardization of antibody assays for measuring the response to pneumococcal infection and immunization. Pediatr Infect Dis J 1989, 8:S84-S91.
14. Koskela M: Serum antibodies to pneumococcal C polysaccharide in children: response to acute pneumococcal otitis media or to vaccination. Pediatr Infect Dis J 1987, 6:519-526.
15. Musher DM, Luchi MJ, Watson DA, Hamilton R, Baughn RE: Pneumococcal polysaccharide vaccine in young adults and older bronchitics: determination of IgG responses by ELISA and the effect of adsorption of serum with non-type-specific cell wall polysaccharide. J Infect Dis 1990, 161:728-735.
16. Concepcion NF, Frasch CE: Pneumococcal type 22f polysaccharide absorption improves the specificity of a pneumococcalpolysaccharide enzyme-linked immunosorbent assay. Clin Diagn Lab Immunol 2001, 8:266-272.
17. Romero-Steiner S, Musher DM, Cetron MS, Pais LB, Groover JE, Fiore AE, Plikaytis BD, Carlone GM: Reduction in functional antibody activity against Streptococcus pneumoniae in vaccinated elderly individuals highly correlates with decreased IgG antibody avidity. Clin Infect Dis 1999, 29:281-288.
18. Rubins JB, Puri AK, Loch J, Charboneau D, MacDonald R, Opstad N, Janoff EN: Magnitude, duration, quality, and function of pneumococcal vaccine responses in elderly adults. J Infect Dis 1998, 178:431-440.
19. Anttila M, Voutilainen M, Jantti V, Eskola J, Kayhty H: Contribution of serotype-specific IgG concentration, IgG subclasses and relative antibody avidity to opsonophagocytic activity against Streptococcus pneumoniae. Clin Exp Immunol 1999, 118:402-407.
20. Lottenbach KR, Mink CM, Barenkamp SJ, Anderson EL, Homan SM, Powers DC: Age-associated differences in immunoglobulin G1 (IgG1) and IgG2 subclass antibodies to pneumococcal polysaccharides following vaccination. Infect Immun 1999, 67:4935-4938.
21. Coughlin RT, White AC, Anderson CA, Carlone GM, Klein DL, Treanor J: Characterization of pneumococcal specific antibodies in healthy unvaccinated adults. Vaccine 1998, 16:1761-1767.
22. Yu X, Gray B, Chang S, Ward JI, Edwards KM, Nahm MH: Immunity to cross-reactive serotypes induced by pneumococcal conjugate vaccines in infants. J Infect Dis 1999, 180:1569-1576.
23. Romero-Steiner S, Musher DM, Cetron MS, Pais LB, Groover JE, Fiore AE, Plikaytis BD, Carlone GM: Reduction in functional antibody activity against Streptococcus pneumoniae in vaccinated elderly individuals highly correlates with decreased IgG antibody avidity [see comments]. Clin Infect Dis 1999, 29:281-288.
24. Sun Y, Hwang Y, Nahm MH: Avidity, potency, and cross-reactivity of monoclonal antibodies to pneumococcal capsular polysaccharide serotype 6B. Infect Immun 2001, 69:336-344.
25. Usinger WR, Lucas AH: Avidity as a determinant of the protective efficacy of human antibodies to pneumococcal capsular polysaccharides. Infect Immun 1999, 67:2366-2370.
26. Wernette CM, Frasch CE, Madore D, Carlone G, Goldblatt D, Plikaytis B, Benjamin W, Quataert SA, Hildreth S, Sikkema DJ, Kayhty H, Jonsdottir I, Nahm MH: Enzyme-linked immunosorbent assay for quantitation of human antibodies to pneumococcal polysaccharides. Clin Diagn Lab Immunol 2003, 10:514-519.
27. Pullen GRFMGHCS: Antibody avidity determination by ELISA using thiocyanate elution. Journal of Immunological Methods 1986, 86:83-87.
28. Romero-Steiner S, Libutti D, Pais LB, Dykes J, Anderson P, Whitin JC, Keyserling HL, Carlone GM: Standardization of an opsonophagocytic assay for the measurement of functional antibody activity against Streptococcus pneumoniae using differentiated HL-60 cells. Clin Diagn Lab Immunol 1997, 4:415-422.