Endometrial histology following 1 year of a continuous daily regimen of levonorgestrel 90 μg/ethinyl estradiol 20 μg

Contraception

Volumn 75, Issue 1, 2007, Pages 23-26

  Johnson, Julia V ^a   Grubb, Gary S ^b   Constantine, Ginger D ^b  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b PFIZER INC   (United States)

Author keywords

Continuous oral contraceptive; Endometrium; Ethinyl estradiol; Levonorgestrel; Safety

Indexed keywords

ETHINYLESTRADIOL PLUS LEVONORGESTREL;

ADULT; AGE DISTRIBUTION; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; DRUG WITHDRAWAL; ENDOMETRIUM; ENDOMETRIUM BIOPSY; ENDOMETRIUM HYPERPLASIA; FEMALE; HISTOLOGY; HUMAN; METRORRHAGIA; MULTICENTER STUDY; NORMAL HUMAN; NORTH AMERICA; ORAL CONTRACEPTION; PHASE 3 CLINICAL TRIAL; PILL; RANDOMIZED CONTROLLED TRIAL; SEXUAL BEHAVIOR; VAGINA BLEEDING;

ADOLESCENT; ADULT; CONTRACEPTIVE AGENTS, FEMALE; ENDOMETRIUM; ESTROGENS; ETHINYL ESTRADIOL; FEMALE; HUMANS; LEVONORGESTREL; METRORRHAGIA; MIDDLE AGED; SAFETY; TREATMENT OUTCOME;

EID: 33845193931     PISSN: 00107824     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.contraception.2006.07.009     Document Type: Article

References (10)

1. The ESHRE Capri Workshop Group. Ovarian and endometrial function during hormonal contraception. Hum Reprod 16 (2001) 1527-1535
2. Coenen C.M., Hollanders J.M., Rolland R., Spielmann D., and Bulten J. The effects of a low-dose gestodene-containing oral contraceptive on endometrial histology in healthy women. Eur J Contracept Reprod Health Care 1 (1996) 325-329
3. Archer D.F. Endometrial histology during use of a low-dose estrogen-desogestrel oral contraceptive with a reduced hormone-free interval. Contraception 60 (1999) 151-154
4. Oosterbaan H.P. An open-label study of the effects of a 24-day regimen of gestodene 60 μg/ethinylestradiol 15 μg on endometrial histological findings in healthy women. Eur J Contracept Reprod Health Care 4 Suppl 2 (1999) 3-8
5. Lüdicke F., Johannisson E., Helmerhorst F.M., Campana A., Foidart J., and Heithecker R. Effect of a combined oral contraceptive containing 3 mg of drospirenone and 30 μg of ethinyl estradiol on the human endometrium. Fertil Steril 76 (2001) 102-107
6. Anderson F.D., Hait H., Hsiu J., Thompson-Graves A.L., Wilborn W.H., and Williams R.F. Endometrial microstructure after long-term use of a 91-day extended-cycle oral contraceptive regimen. Contraception 71 (2005) 55-59
7. Miller L., and Hughes J.P. Continuous combination oral contraceptive pills to eliminate withdrawal bleeding: a randomized trial. Obstet Gynecol 101 (2003) 653-661
8. Archer DF, Jensen JT, Johnson JV, Borisute H, Grubb GS, Constantine G. Evaluation of a continuous regimen of levonorgestrel/ethinyl estradiol: phase 3 study results. Contraception [in press].
9. In: Kurman R.J. (Ed). Blaustein's pathology of the female genital tract. 5th ed. (2002), Springer, New York
10. Kaunitz A.M. Long-acting injectable contraception with depot medroxyprogesterone acetate. Am J Obstet Gynecol 170 (1994) 1543-1549