Can context justify an ethical double standard for clinical research in developing countries?

Globalization and Health

Volumn 1, Issue , 2005, Pages

  Landes, Megan ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PLACEBO;

AFRICA; ARTICLE; ASIA; BENEFICENCE; CENTRAL AMERICA; CLINICAL RESEARCH; CLINICAL STUDY; CONSENSUS; DEVELOPING COUNTRY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN RIGHTS; METHODOLOGY; PRIORITY JOURNAL; RESEARCH ETHICS; STANDARD; VIRUS TRANSMISSION;

EID: 33845192183     PISSN: 17448603     EISSN: None     Source Type: Journal    
DOI: 10.1186/1744-8603-1-11     Document Type: Article

References (24)

1. Olweny C: Bioethics in developing countries: ethics of scarcity and sacrifice. Journal of Medical Ethics 1994, 20:169-174.
2. Angell M: The Ethics of Clinical Research in the Third World. New England Journal of Medicine 1997, 337(12):847-849.
3. Bayer R: The Debate over Maternal-Fetal HIV Transmission Prevention Trials in Africa, Asia, and the Caribbean: Racist Exploitation or Exploitation of Racism? American Journal of Public Health 1998, 88(4):567-570.
4. Levine C: Placebos and HIV: Lessons Learned. Hastings Centre Report 1998, 28(6):43-48.
5. Waluchow W, Thomas J: Ethical Frameworks for Decision-Making. In Well and Good: Case Studies in Biomedical Ethics Edited by: Waluchow W, Thomas J. USA: Broadview Press; 1998.
6. Sherwin S: No Longer Patient USA: Temple University Press; 1992.
7. Lurie P, Wolfe S: Unethical Trials of Interventions to Reduce Perinatal Transmission of the Human Immunodeficiency Virus in Developing Countries. New England Journal of Medicine 1997, 337:853-856.
8. Sen A: Development as Freedom New York: Anchor Books; 1999.
9. Sparr P, (ed): Mortgaging Women's Lives London: Zed Books; 1994.
10. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research: The Belmont Report Washington, DC; 1978.
11. Satcher D, Varmus H: Ethical Complexities of Conducting Research in Developing Countries. New England Journal of Medicine 1998, 337(14):1003-1005.
12. Annas G, Grodin M: Human Rights and Maternal-Fetal HIV Transmission Prevention Trials in Africa. American Journal of Public Health 1998, 88(4):560-563.
13. Mofenson L: Tale of two epidemics: the continuing challenge of preventing mother-to-child transmission of human immunodeficiency virus. J Infect Dis 2003, 187:721-724.
14. UNAIDS: Progress Report on the Global Response to the HIV/AIDS Epidemic Geneva; 2003.
15. UNAIDS: Progress Report on the Global Response to the HIV/AIDS Epidemic Geneva; 2003.
16. Annas G, Grodin M: Human Rights and Maternal-Fetal HIV Transmission Prevention Trials in Africa. American Journal of Public Health 1998, 88(4):560-563.
17. Jackson JB, Musoke P, Fleming T: Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: 18 month followup to the HIVNET012 randomized trial. Lancet 2003, 362:59-68.
18. Dorenbaum A, Cunnigham CK, Gelber RD, Culnane M, Mofenson L, Briotto P, Rekacewicz C, Newell ML, Delfraissy JF, Cunnigham-Schrader B, Mirochnick M, Sullivan JL: Two-dose intrapartum/newborn nevirapine and standard antiretroviral therapy to reduce perinatal HIV transmission: a randomized trial. JAMA 2002, 288(2):189-98.
19. Wendler D, Emanuel EJ, Lie RK: The Standard of Care Debate: Can Research in Developing Countries Be Both Ethical and Responsive to Those Countries's Health Needs? American Journal of Public Health 2004, 94(6):923-928.
20. Tangwa GB: Between universalism and relativism: a conceptual exploration of problems in formulating and applying international biomedical ethical guidelines. J Med Ethics 2004, 30:63-67.
21. Lie RK, Emanuel E, Grady C, Wendler: The standard of care debate: the Declaration of Helsinki versus the international consensus opinion. J Med Ethics 2004, 30:190-193.
22. McMillan JR, Conlon C: The ethics of research related to health care in developing countries. J Med Ethics 2004, 30:204-206.
23. McMillan JR, Conlon C: The ethics of research related to health care in developing countries. J Med Ethics 2004, 30:204-206.
24. Schuklenk U: The standard of care debate: against the myth of an "international consensus opinion.". J Med Ethics 2004, 30:194-197.