Bioassay-guided isolation of antimalarial triterpenoid acids from the leaves of Morinda lucida

Pharmaceutical Biology

Volumn 44, Issue 9, 2006, Pages 677-681

  Cimanga, Richard K ^a,b   Tona, Gaston L ^b   Mesia, Gauthier K ^a,b   Kambu, Oscar K ^b   Bakana, Donatien P ^b   Kalenda, Pascal D T ^b   Penge, Auguste O ^b   Muyembe, Jean Jacques T ^c   Totté, Jozef ^a   Pieters, Luc ^a   Vlietinck, Arnold J ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b UNIVERSITY OF KINSHASA   (Congo)

^c Institut National de la Recherche Biomédicale INRB   (Congo)

Author keywords

In vivo antimalarial activity; Morinda lucida; Oleanolic acid; Plasmodium berghei berghei Plasmodium falciparum; Rubiaceae; Triterpenic acids; Ursolic acid

Indexed keywords

ALCOHOL; ANTIMALARIAL AGENT; CHLOROQUINE; DICHLOROMETHANE; MORINDA LUCIDA EXTRACT; OLEANOLIC ACID; PETROLEUM ETHER; PLANT EXTRACT; TRITERPENOID; UNCLASSIFIED DRUG; URSOLIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; BIOASSAY; BODY WEIGHT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; IC 50; IN VIVO STUDY; MEDICINAL PLANT; MORINDA LUCIDA; MOUSE; NONHUMAN; PARASITEMIA; PLANT LEAF; PLASMODIUM BERGHEI; PLASMODIUM BERGHEI BERGHEI; PLASMODIUM FALCIPARUM;

MORINDA LUCIDA; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; RUBIACEAE;

EID: 33751570530     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.1080/13880200601009123     Document Type: Article

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